Search Results - "Tieleman, P"

Work participation, social roles, and empowerment of Q-fever fatigue syndrome patients ≥10 years after infection by Brus, I M, Teng, A S J, Heemskerk, S C M, Polinder, S, Tieleman, P, Hartman, E, Dollekens, B, Haagsma, J A, Spronk, I

“…To determine work participation, social roles, and empowerment of QFS patients ≥10-year after infection. QFS patients ≥10-year after acute infection, who were…”
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Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function by Ramezanpour, M, Schmidt, M L, Bodnariuc, I, Kulkarni, J A, Leung, S S W, Cullis, P R, Thewalt, J L, Tieleman, D P

“…Lipid nanoparticles (LNPs) composed of ionizable cationic lipids are currently the leading systems for siRNA delivery in liver disease, with the major…”
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Molecular Ordering in Lipid Monolayers: An Atomistic Simulation by Panzuela, S, Tieleman, D. P, Mederos, L, Velasco, E

“…We report on atomistic simulations of DPPC lipid monolayers using the CHARMM36 lipid force field (and also the Slipid force field as a control case), combined…”
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Structural Properties of Inverted Hexagonal Phase: A Hybrid Computational and Experimental Approach by Ramezanpour, M, Schmidt, M. L, Bashe, B. Y. M, Pruim, J. R, Link, M. L, Cullis, P. R, Harper, P. E, Thewalt, J. L, Tieleman, D. P

“…Inverted/reverse hexagonal (HII) phases are of special interest in several fields of research, including nanomedicine. We used molecular dynamics (MD)…”
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Molecular Dynamics Simulation of the Kinetics of Spontaneous Micelle Formation by Marrink, S. J, Tieleman, D. P, Mark, A. E

“…Using an atom based force field, molecular dynamics (MD) simulations of 54 dodecylphosphocholine (DPC) surfactant molecules in water at two different…”
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Molecular Dynamics Simulations of Dodecylphosphocholine Micelles at Three Different Aggregate Sizes:  Micellar Structure and Chain Relaxation by Tieleman, D. P, van der Spoel, D, Berendsen, H. J. C

“…We simulated micelles of 40 (M40), 54 (M54), and 65 (M65) dodecylphosphocholine (DPC) lipids in water for up to 15 ns and analyzed the system energetics,…”
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Antimicrobial Peptides in the Cross Hairs of Computer Simulations by Tieleman, D.P.

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A Molecular Dynamics Study of the Pores Formed by Escherichia coli OmpF Porin in a Fully Hydrated Palmitoyloleoylphosphatidylcholine Bilayer by Tieleman, D.P., Berendsen, H.J.C.

“…In this paper we study the properties of pores formed by OmpF porin from Escherichia coli, based on a molecular dynamics simulation of the OmpF trimer, 318…”
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Computational and experimental approaches for investigating nanoparticle-based drug delivery systems by Ramezanpour, M., Leung, S.S.W., Delgado-Magnero, K.H., Bashe, B.Y.M., Thewalt, J., Tieleman, D.P.

“…Most therapeutic agents suffer from poor solubility, rapid clearance from the blood stream, a lack of targeting, and often poor translocation ability across…”
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Voltage-Dependent Insertion of Alamethicin at Phospholipid/Water and Octane/Water Interfaces by Tieleman, D.P., Berendsen, H.J.C., Sansom, M.S.P.

“…Understanding the binding and insertion of peptides in lipid bilayers is a prerequisite for understanding phenomena such as antimicrobial activity and…”
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Insights Into the Na+‐Dependent Anion Exchange in the SLC4 Family From the Cryo‐EM Structure of the Sodium‐Driven Chloride/Bicarbonate Exchanger SLC4A8 by Zhekova, Hristina R., Wang, Weiguang, Tsirulnikov, Kirill, Kayık, Gülru, Khan, Hanif M., Azimov, Rustam, Abuladze, Natalia, Kao, Liyo, Newman, Debbie, Noskov, Sergei, Tieleman, D. P., Zhou, Z. H., Pushkin, Alexander, Kurtz, Ira

“…SLC4 transporters are involved in the transport of HCO3‾, CO32‾, Na+, Cl‾ and H+ required for regulation of pH and ion homeostasis in several important…”
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Insights into lipid-protein interactions from computer simulations by Tieleman, D. P., Sejdiu, B. I., Cino, E. A., Smith, P., Barreto-Ojeda, E., Khan, H. M., Corradi, V.

“…Lipid-protein interactions play an important direct role in the function of many membrane proteins. We argue they are key players in membrane structure,…”
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Molecular Dynamics Simulation of a Lipid Diamond Cubic Phase by Marrink, Siewert-Jan, Tieleman, D. Peter

“…This paper presents the first atomistic simulation of a cubic membrane phase. Using the molecular dynamics simulation technique both the global and the local…”
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Molecular dynamics simulations of antimicrobial peptides: From membrane binding to trans-membrane channels by Tieleman, D. P., Sansom, M. S. P.

“…Using a combination of simulations of alamethicin and other antimicrobial peptides in different environments, we discuss a number of pertinent problems in the…”
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A computer perspective of membranes: molecular dynamics studies of lipid bilayer systems by Tieleman, D.P, Marrink, S.J, Berendsen, H.J.C

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Interactions of key charged residues contributing to selective block of neuronal sodium channels by μ-conotoxin KIIIA by McArthur, J R, Singh, G, McMaster, D, Winkfein, R, Tieleman, D P, French, R J

“…Voltage-gated sodium channels are important in initiating and propagating nerve impulses in various tissues, including cardiac muscle, skeletal muscle, the…”
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Structure and Aggregation Number of a Lyotropic Liquid Crystal:  A Fluorescence Quenching and Molecular Dynamics Study by Montecinos, R, Ahumada, H, Martínez, R, Olea, F. A, Araya-Maturana, R, Aliste, M. P, Tieleman, D. P, Weiss-López, B. E

“…The structure and aggregation number of a discotic lyotropic liquid crystal, prepared from tetradecyltrimethylammonium chloride (TDTMACl)/decanol…”
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Orientation and Dynamics of Benzyl Alcohol and Benzyl Alkyl Ethers Dissolved in Nematic Lyotropic Liquid Crystals. 2H NMR and Molecular Dynamics Simulations by Ahumada, H, Montecinos, R, Tieleman, D. P, Weiss-López, B. E

“…Most drugs have to cross cell membranes to reach their final target. A better understanding of the distribution, interactions, and dynamics of biologically…”
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Self-perceived barriers to healthcare access for patients with post COVID-19 condition by Brus, I, Spronk, I, Heemskerk, SCM, Biere-Rafi, S, Tieleman, P, Polinder, S, Haagsma, J A

“…Abstract Background Many patients with post COVID-19 condition (PCC) require healthcare services. However, qualitative studies indicate that patients with PCC…”
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Atoms to Phenotypes: Molecular Design Principles of Cellular Energy Metabolism by Singharoy, Abhishek, Maffeo, Christopher, Delgado-Magnero, Karelia H., Swainsbury, David J.K., Sener, Melih, Kleinekathöfer, Ulrich, Vant, John W., Nguyen, Jonathan, Hitchcock, Andrew, Isralewitz, Barry, Teo, Ivan, Chandler, Danielle E., Stone, John E., Phillips, James C., Pogorelov, Taras V., Mallus, M. Ilaria, Chipot, Christophe, Luthey-Schulten, Zaida, Tieleman, D. Peter, Hunter, C. Neil, Tajkhorshid, Emad, Aksimentiev, Aleksei, Schulten, Klaus

“…We report a 100-million atom-scale model of an entire cell organelle, a photosynthetic chromatophore vesicle from a purple bacterium, that reveals the cascade…”
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