Search Results - "Tiefenbacher, Konrad"

Brønsted Acid‐Catalyzed Carbonyl‐Olefin Metathesis inside a Self‐Assembled Supramolecular Host by Catti, Lorenzo, Tiefenbacher, Konrad

“…Carbonyl–olefin metathesis represents a powerful yet underdeveloped method for the formation of carbon–carbon bonds. So far, no Brønsted acid based method for…”
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Catalysis inside the Hexameric Resorcinarene Capsule by Zhang, Qi, Catti, Lorenzo, Tiefenbacher, Konrad

“…Conspectus In this Account, we outline our investigation into the supramolecular resorcinarene capsule as a catalyst. Molecular capsules not only are of…”
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Hexameric Resorcinarene Capsule is a Brønsted Acid: Investigation and Application to Synthesis and Catalysis by Zhang, Qi, Tiefenbacher, Konrad

“…Molecular capsules have attracted interest as simple enzyme mimetics and several examples of catalytic transformations in water-soluble metal–ligand based…”
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Advantages of Catalysis in Self-Assembled Molecular Capsules by Catti, Lorenzo, Zhang, Qi, Tiefenbacher, Konrad

“…Control over the local chemical environment of a molecule can be achieved by encapsulation in supramolecular host systems. In supramolecular catalysis, this…”
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Synthesis of Lactones via C–H Functionalization of Nonactivated C(sp3)–H Bonds by Richers, Johannes, Heilmann, Michael, Drees, Markus, Tiefenbacher, Konrad

“…An electron-deficient amide is utilized as a directing group to functionalize nonactivated C­(sp3)–H bonds through radical 1,5-hydrogen abstraction. The…”
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Iminium Catalysis inside a Self-Assembled Supramolecular Capsule: Modulation of Enantiomeric Excess by Bräuer, Thomas M., Zhang, Qi, Tiefenbacher, Konrad

“…The noncovalent combination of a supramolecular host with iminium organocatalysis is described. Due to cation–π interactions the reactive iminium species is…”
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Synthesis of Platensimycin by Tiefenbacher, Konrad, Mulzer, Johann

“…In modern drug discovery, antibodies or libraries of simple synthetic organic compounds, mostly of heterocyclic origin, are favored. Natural products play an…”
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Iminium Catalysis inside a Self-Assembled Supramolecular Capsule: Scope and Mechanistic Studies by Bräuer, Thomas M, Zhang, Qi, Tiefenbacher, Konrad

“…Although iminium catalysis has become an important tool in organic chemistry, its combination with supramolecular host systems has remained largely unexplored…”
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Expanding the Protecting Group Scope for the Carbonyl Olefin Metathesis Approach to 2,5-Dihydropyrroles by Huck, Fabian, Catti, Lorenzo, Reber, Gian Lino, Tiefenbacher, Konrad

“…Chiral pyrrolidine derivatives are important building blocks for natural product synthesis. Carbonyl olefin metathesis has recently emerged as a powerful tool…”
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Molecular Capsule Catalysis: Ready to Address Current Challenges in Synthetic Organic Chemistry? by Némethová, Ivana, Syntrivanis, Leonidas-Dimitrios, Tiefenbacher, Konrad

“…Self-assembled molecular capsules, host structures that form spontaneously when their building blocks are mixed, have been known since the 1990s. They share…”
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Short Formal Synthesis of (−)-Platencin by Tiefenbacher, Konrad, Mulzer, Johann

“…Short and sweet: A five‐step, protecting‐group‐free formal synthesis of (−)‐platencin from commercially available (−)‐perillaldehyde (see retrosynthetic…”
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A Nine-Step Total Synthesis of (−)-Platencin by Tiefenbacher, Konrad, Mulzer, Johann

“…Within 1 year, platencin, a recently discovered antibiotic, has become a highly competitive synthetic target, due to its promising bioactivity and its unusual…”
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Protecting-Group-Free Formal Synthesis of Platensimycin by Tiefenbacher, Konrad, Mulzer, Johann

“…Short cut: In a new approach to the recently discovered antibiotic platensimycin (1), Nicolaou's late key intermediate is synthesised without the use of…”
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Chirality Induction from a Chiral Guest to the Hydrogen‐Bonding Network of Its Hexameric Resorcinarene Host Capsule by Pollok, Corina H., Zhang, Qi, Tiefenbacher, Konrad, Merten, Christian

“…The hexameric capsule of resorcin[4]arene 1 is capable of encapsulating tertiary amines, which has recently been used in the application of [(1)6(H2O)8] as…”
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Xanthene[n]arenes: Exceptionally Large, Bowl-Shaped Macrocyclic Building Blocks Suitable for Self-Assembly by Pfeuffer-Rooschüz, Jonathan, Schmid, Lucius, Prescimone, Alessandro, Tiefenbacher, Konrad

“…A new class of macrocycles denoted as “xanthene­[n]­arenes” was synthesized. In contrast to most other macrocycles, they feature a conformationally restricted…”
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Quantification of α-Thujone and Its Metabolites in Human Urine after Consumption of a Sage Infusion Using Stable Isotope Dilution Assays by Thamm, Irene, Tiefenbacher, Konrad, Rychlik, Michael

“…The metabolism of the monoterpene α-thujone was investigated in humans after consumption of sage tea, by analyses of its metabolites 2-hydroxythujone,…”
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Syntheses and Antibacterial Properties of iso-Platencin, Cl-iso-Platencin and Cl-Platencin: Identification of a New Lead Structure by Tiefenbacher, Konrad, Gollner, Andreas, Mulzer, Johann

“…Platencin is a novel antibiotic which is active against multiresistant pathogens. We describe efficient syntheses of three platencin analogues of varying…”
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Total Syntheses of (+)-Echinopine A and B: Determination of Absolute Stereochemistry by Magauer, Thomas, Mulzer, Johann, Tiefenbacher, Konrad

“…The first total syntheses of the novel 3,5,5,7-sesquiterpenoids (+)-Echinopine A (1) and B (2) were achieved. Thereby the proposed structures were confirmed,…”
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Window[1]resorcin[3]arenes: A Novel Macrocycle Able to Self-Assemble to a Catalytically Active Hexameric Cage by Li, Tian-Ren, Das, Chintu, Cornu, Ivan, Prescimone, Alessandro, Piccini, GiovanniMaria, Tiefenbacher, Konrad

“…The hexameric resorcin[4]­arene capsule has been utilized as one of the most versatile supramolecular capsule catalysts. Enlarging its size would enable…”
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Tertiary Alcohols as Substrates for SN2-Like Stereoinversion by Räder, Andreas F. B., Tiefenbacher, Konrad

“…Rewrite the textbooks! The stereospecific bimolecular substitution reaction (SN2) is usually limited to primary and secondary electrophiles. The Shenvi group…”
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