Search Results - "Tice, Caitlin"

A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening by Beshiri, Michael L, Tice, Caitlin M, Tran, Crystal, Nguyen, Holly M, Sowalsky, Adam G, Agarwal, Supreet, Jansson, Keith H, Yang, Qi, McGowen, Kerry M, Yin, JuanJuan, Alilin, Aian Neil, Karzai, Fatima H, Dahut, William L, Corey, Eva, Kelly, Kathleen

“…Prostate cancer translational research has been hampered by the lack of comprehensive and tractable models that represent the genomic landscape of clinical…”
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Clinical and translational advances in esophageal squamous cell carcinoma by Reichenbach, Zachary Wilmer, Murray, Mary Grace, Saxena, Reshu, Farkas, Daniel, Karassik, Erika G, Klochkova, Alena, Patel, Kishan, Tice, Caitlin, Hall, Timothy M, Gang, Julie, Parkman, Henry P, Ward, Sarah J, Tétreault, Marie-Pier, Whelan, Kelly A

“…Esophageal squamous cell carcinoma (ESCC) is among the most deadly forms of human malignancy characterized by late stage diagnosis, metastasis, therapy…”
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Astrocytes, HIV and the Glymphatic System: A Disease of Disrupted Waste Management? by Tice, Caitlin, McDevitt, Jane, Langford, Dianne

“…The discovery of the glial-lymphatic or glymphatic fluid clearance pathway in the rodent brain led researchers to search for a parallel system in humans and to…”
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Stem cell dynamics and cellular heterogeneity across lineage subtypes of castrate-resistant prostate cancer by Beshiri, Michael L, Capaldo, Brian J, Lake, Ross, Ku, Anson T, Burner, Danielle, Tice, Caitlin M, Tran, Crystal, Kostas, Julianna, Alilin, Aian Neil, Yin, JuanJuan, Agarwal, Supreet, Morris, Samantha A, Karzai, Fatima H, Lotan, Tamara L, Dahut, William L, Sowalsky, Adam G, Kelly, Kathleen

“…To resist lineage-dependent therapies such as androgen receptor inhibition, prostate luminal epithelial adenocarcinoma cells often adopt a stem-like state…”
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High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer by Jansson, Keith H., Tucker, John B., Stahl, Lauren E., Simmons, John K., Fuller, Caitlyn, Beshiri, Michael L., Agarwal, Supreet, Fang, Lei, Hynes, Paul G., Alilin, Aian Neil, Lake, Ross, Abbey, Yasmine C., Cawley, Jacob, Tice, Caitlin M., Yin, JuanJuan, McKnight, Crystal, Klummp-Thomas, Carleen, Zhang, Xiaohu, Guha, Rajarshi, Hoover, Shelley, Simpson, R. Mark, Nguyen, Holly M., Corey, Eva, Thomas, Craig J., Proia, David A., Kelly, Kathleen

“…The development of new treatments for castrate resistant prostate cancer (CRPC) must address such challenges as intrinsic tumor heterogeneity and phenotypic…”
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Single nucleotide polymorphisms in aquaporin-4 associate with cognitive impairment status in people with HIV by Tice, Caitlin, Zhao, Huaqing, Langford, Dianne

“…Neurocognitive impairments are more frequent in people with HIV (PWH) compared to their uninfected counterparts. HIV-associated neurocognitive disorder (HAND)…”
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Relationships between plasma neurofilament light chain protein, cognition, and brain aging in people with HIV by Cooley, Sarah A, Petersen, Kalen J, Tice, Caitlin, Langford, Dianne, Burdo, Tricia H, Roman, June, Ances, Beau M

“…Neurofilament light chain protein (NfL) is a marker of neuronal injury and neurodegeneration. Typically assessed in cerebrospinal fluid, recent advances have…”
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Abstract 5020: A patient-derived organoid model of neuroendocrine prostate cancer transdifferentiation informing the role of the BAF complex component ARID1A by Beshiri, Mike L., Tice, Caitlin M., Sowalsky, Adam G., Tran, Crystal, Karzai, Fatima, Dahut, William, Kelly, Kathy

“…Metastatic castration-resistant prostate cancer (mCRPC) is a genetically and phenotypically heterogeneous disease. Resistance to contemporary…”
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Abstract 4838: Optimization of prostate cancer organoid culture methods to grow PDX and human biopsy tissue by Beshiri, Mike L., Tran, Crystal, Sowalsky, Adam G., Nguyen, Holly M., Agarwal, Supreet, Tice, Caitlin M., Corey, Eva, Kelly, Kathy

“…A major obstacle in the field of prostate cancer research is the limited capacity to culture prostate cancer-derived cells in vitro. There are relatively few…”
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Abstract B051: PDX-derived and patient-derived prostate cancer organoids as a clinically relevant platform for translational research by Beshiri, Michael L., Tice, Caitlin M., Tran, Crystal, Nguyen, Holly M., Sowalsky, Adam G., Agarwal, Supreet, Jansson, Keith H., McGowen, Kerry, Alilin, Aian Neil, Yin, JuanJuan, Karzai, Fatima H., Dahut, William L., Corey, Eva, Kelly, Kathleen

“…Metastatic castration-resistant prostate cancer (CRPC) is a genetically heterogeneous disease. Effective translational research demands a diverse and…”
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Abstract B018: A high-throughput screen identifies HSP90 inhibitors as potent therapeutics across multiple clinically representative organoid models of advanced prostate cancer by Jansson, Keith H., Tucker, John B., Stahl, Lauren E., Simmons, John K., Fuller, Caitlyn, Beshiri, Michael L., Agarwal, Supreet, Abbey, Yasmine, Fang, Lei, Hynes, Paul G., Neil, Alilin Aian, Cawley, Jacob, Lake, Ross, Tran, Crystal, Tice, Caitlin M., Yin, JuanJuan, Zhang, Xiahu, Guha, Rajarshi, Hoover, Shelley, Simpson, R. Mark, Nguyen, Holly, Corey, Eva, Thomas, Craig J., Proia, David, Kelly, Kathleen

“…Androgen-deprivation therapy (ADT) remains the gold-standard therapy for prostate cancer (PrCa), and although ADT is initially effective, most men progress to…”
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