Search Results - "Tice, A"

Antibody-Drug Conjugates: Future Directions in Clinical and Translational Strategies to Improve the Therapeutic Index by Coats, Steven, Williams, Marna, Kebble, Benjamin, Dixit, Rakesh, Tseng, Leo, Yao, Nai-Shun, Tice, David A, Soria, Jean-Charles

“…Since the first approval of gemtuzumab ozogamicin (Mylotarg; Pfizer; CD33 targeted), two additional antibody-drug conjugates (ADC), brentuximab vedotin…”
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Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial by Shieh, Yiwey, Eklund, Martin, Madlensky, Lisa, Sawyer, Sarah D, Thompson, Carlie K, Stover Fiscalini, Allison, Ziv, Elad, Van't Veer, Laura J, Esserman, Laura J, Tice, Jeffrey A

“…Ongoing controversy over the optimal approach to breast cancer screening has led to discordant professional society recommendations, particularly in women age…”
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Cost-effectiveness of Early Treatment of Hepatitis C Virus Genotype 1 by Stage of Liver Fibrosis in a US Treatment-Naive Population by Chahal, Harinder S, Marseille, Elliot A, Tice, Jeffrey A, Pearson, Steve D, Ollendorf, Daniel A, Fox, Rena K, Kahn, James G

“…Novel treatments for hepatitis C virus (HCV) infection are highly efficacious but costly. Thus, many insurers cover therapy only in advanced fibrosis stages…”
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Using Clinical Factors and Mammographic Breast Density to Estimate Breast Cancer Risk : Development and Validation of a New Predictive Model by TICE, Jeffrey A, CUMMINGS, Steven R, SMITH-BINDMAN, Rebecca, ICHIKAWA, Laura, BARLOW, William E, KERLIKOWSKE, Karla

“…Current models for assessing breast cancer risk are complex and do not include breast density, a strong risk factor for breast cancer that is routinely…”
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Breast cancer risk prediction using a clinical risk model and polygenic risk score by Shieh, Yiwey, Hu, Donglei, Ma, Lin, Huntsman, Scott, Gard, Charlotte C., Leung, Jessica W. T., Tice, Jeffrey A., Vachon, Celine M., Cummings, Steven R., Kerlikowske, Karla, Ziv, Elad

“…Breast cancer risk assessment can inform the use of screening and prevention modalities. We investigated the performance of the Breast Cancer Surveillance…”
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MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer by Greer, Yoshimi Endo, Gilbert, Samuel F, Gril, Brunilde, Narwal, Rajesh, Peacock Brooks, Danielle L, Tice, David A, Steeg, Patricia S, Lipkowitz, Stanley

“…TNF-related apoptosis-inducing ligand (TRAIL) receptor agonists are attractive anti-tumor agents because of their capability to induce apoptosis in cancer…”
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SLC46A3 as a Potential Predictive Biomarker for Antibody-Drug Conjugates Bearing Noncleavable Linked Maytansinoid and Pyrrolobenzodiazepine Warheads by Kinneer, Krista, Meekin, John, Tiberghien, Arnaud C, Tai, Yu-Tzu, Phipps, Sandrina, Kiefer, Christine Mione, Rebelatto, Marlon C, Dimasi, Nazzareno, Moriarty, Alyssa, Papadopoulos, Kyriakos P, Sridhar, Sriram, Gregson, Stephen J, Wick, Michael J, Masterson, Luke, Anderson, Kenneth C, Herbst, Ronald, Howard, Philip W, Tice, David A

“…Antibody-drug conjugates (ADC) utilizing noncleavable linker drugs have been approved for clinical use, and several are in development targeting solid and…”
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The contributions of breast density and common genetic variation to breast cancer risk by Vachon, Celine M, Pankratz, V Shane, Scott, Christopher G, Haeberle, Lothar, Ziv, Elad, Jensen, Matthew R, Brandt, Kathleen R, Whaley, Dana H, Olson, Janet E, Heusinger, Katharina, Hack, Carolin C, Jud, Sebastian M, Beckmann, Matthias W, Schulz-Wendtland, Ruediger, Tice, Jeffrey A, Norman, Aaron D, Cunningham, Julie M, Purrington, Kristen S, Easton, Douglas F, Sellers, Thomas A, Kerlikowske, Karla, Fasching, Peter A, Couch, Fergus J

“…We evaluated whether a 76-locus polygenic risk score (PRS) and Breast Imaging Reporting and Data System (BI-RADS) breast density were independent risk factors…”
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Prevention of Breast Cancer in Postmenopausal Women: Approaches to Estimating and Reducing Risk by Cummings, Steven R., Tice, Jeffrey A., Bauer, Scott, Browner, Warren S., Cuzick, Jack, Ziv, Elad, Vogel, Victor, Shepherd, John, Vachon, Celine, Smith-Bindman, Rebecca, Kerlikowske, Karla

“…Background It is uncertain whether evidence supports routinely estimating a postmenopausal woman's risk of breast cancer and intervening to reduce risk…”
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Gastric Banding or Bypass? A Systematic Review Comparing the Two Most Popular Bariatric Procedures by Tice, Jeffrey A., MD, Karliner, Leah, MD, MS, Walsh, Judith, MD, Petersen, Amy J., PhD, Feldman, Mitchell D., MD, MPhil

“…Abstract Objective Bariatric surgical procedures have increased exponentially in the United States. Laparoscopic adjustable gastric banding is now promoted as…”
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Effects of isoflavones on breast density in pre- and post-menopausal women: a systematic review and meta-analysis of randomized controlled trials by Hooper, Lee, Madhavan, Giri, Tice, Jeffrey A., Leinster, Sam J., Cassidy, Aedín

“…BACKGROUND Isoflavones from soy and red clover exert modest hormonal effects in women, but the relevance to risk of breast cancer is unclear. The aim of this…”
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A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth by Streicher, K L, Zhu, W, Lehmann, K P, Georgantas, R W, Morehouse, C A, Brohawn, P, Carrasco, R A, Xiao, Z, Tice, D A, Higgs, B W, Richman, L, Jallal, B, Ranade, K, Yao, Y

“…Malignant melanoma is the most aggressive form of skin cancer and its incidence has doubled in the last two decades. It represents only 4% of skin cancer cases…”
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Assessing the value of mepolizumab for severe eosinophilic asthma: a cost-effectiveness analysis by Whittington, Melanie D., MS, McQueen, R. Brett, PhD, Ollendorf, Daniel A., PhD, Tice, Jeffrey A., MD, Chapman, Richard H., PhD, MS, Pearson, Steven D., MD, MSc, Campbell, Jonathan D., PhD

“…Abstract Background Adding mepolizumab to standard treatment with inhaled corticosteroids and controller medications could decrease asthma exacerbations and…”
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Prospective Breast Cancer Risk Prediction Model for Women Undergoing Screening Mammography by Barlow, William E., White, Emily, Ballard-Barbash, Rachel, Vacek, Pamela M., Titus-Ernstoff, Linda, Carney, Patricia A., Tice, Jeffrey A., Buist, Diana S. M., Geller, Berta M., Rosenberg, Robert, Yankaskas, Bonnie C., Kerlikowske, Karla

“…Background: Risk prediction models for breast cancer can be improved by the addition of recently identified risk factors, including breast density and use of…”
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EphB4 promotes or suppresses Ras/MEK/ERK pathway in a context-dependent manner: Implications for EphB4 as a cancer target by Xiao, Zhan, Carrasco, Rosa, Kinneer, Krista, Sabol, Darrin, Jallal, Bahija, Coats, Steve, Tice, David A.

“…EphB4 is a member of the Eph receptor tyrosine kinase family shown to act in neuronal guidance and mediate venal/arterial separation. In contrast to these more…”
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A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways by Rios-Doria, Jonathan, Sabol, Darrin, Chesebrough, Jon, Stewart, Dave, Xu, Linda, Tammali, Ravinder, Cheng, Li, Du, Qun, Schifferli, Kevin, Rothstein, Ray, Leow, Ching Ching, Heidbrink-Thompson, Jenny, Jin, Xiaofang, Gao, Changshou, Friedman, Jay, Wilkinson, Brandy, Damschroder, Melissa, Pierce, Andrew J, Hollingsworth, Robert E, Tice, David A, Michelotti, Emil F

“…ADAM17 is the primary sheddase for HER pathway ligands. We report the discovery of a potent and specific ADAM17 inhibitory antibody, MEDI3622, which induces…”
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Using Breast Cancer Risk Associated Polymorphisms to Identify Women for Breast Cancer Chemoprevention by Ziv, Elad, Tice, Jeffrey A, Sprague, Brian, Vachon, Celine M, Cummings, Steven R, Kerlikowske, Karla

“…Breast cancer can be prevented with selective estrogen receptor modifiers (SERMs) and aromatase inhibitors (AIs). The US Preventive Services Task Force…”
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Estrogen metabolism and breast cancer risk among postmenopausal women: a case-cohort study within B~FIT by Dallal, Cher M, Tice, Jeffrey A, Buist, Diana S M, Bauer, Douglas C, Lacey, Jr, James V, Cauley, Jane A, Hue, Trisha F, Lacroix, Andrea, Falk, Roni T, Pfeiffer, Ruth M, Fuhrman, Barbara J, Veenstra, Timothy D, Xu, Xia, Brinton, Louise A

“…Although elevated circulating estrogens are associated with increased postmenopausal breast cancer risk, less is known regarding the role of estrogen…”
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Multivalent scaffold proteins as superagonists of TRAIL receptor 2-induced apoptosis by Swers, Jeffery S, Grinberg, Luba, Wang, Lin, Feng, Hui, Lekstrom, Kristen, Carrasco, Rosa, Xiao, Zhan, Inigo, Ivan, Leow, Ching Ching, Wu, Herren, Tice, David A, Baca, Manuel

“…Activation of TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2) can induce apoptosis in a variety of human cancer cell lines and xenografts, while…”
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Mechanism of Biological Synergy between Cellular Src and Epidermal Growth Factor Receptor by Tice, David A., Biscardi, Jacqueline S., Nickles, Amanda L., Parsons, Sarah J.

“…Overexpression of both cellular Src (c-Src) and the epidermal growth factor receptor (EGFR) occurs in many of the same human tumors, suggesting that they may…”
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