Search Results - "Tiberio, Laura"
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1
Cytokine Targeting by miRNAs in Autoimmune Diseases
Published in Frontiers in immunology (2019)“…Persistent and excessive cytokine production is a hallmark of autoimmune diseases and may play a role in disease pathogenesis and amplification. Therefore,…”
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2
Chemokine and chemotactic signals in dendritic cell migration
Published in Cellular & molecular immunology (01-04-2018)“…Dendritic cells (DCs) are professional antigen-presenting cells responsible for the activation of specific T-cell responses and for the development of immune…”
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3
Sonicated pineapple juice as substrate for L. casei cultivation for probiotic beverage development: Process optimisation and product stability
Published in Food chemistry (15-08-2013)“…► Sonicated pineapple juice was fermented by Lactobacillus casei. ► The product shelf life was 21days under refrigeration (4°C). ► The product presented post…”
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4
Power ultrasound processing of cantaloupe melon juice: Effects on quality parameters
Published in Food research international (01-08-2012)“…The effects of ultrasound process on quality parameters and on peroxidase (POD), polyphenol oxidase (PPO) and ascorbate peroxidase (APx) activities of…”
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5
High-Intensity Ultrasound Processing of Pineapple Juice
Published in Food and bioprocess technology (01-04-2013)“…The influence of ultrasound processing on the physicochemical characteristics of pineapple juice was investigated through an experimental design changing…”
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6
Functional Role of Dendritic Cell Subsets in Cancer Progression and Clinical Implications
Published in International journal of molecular sciences (30-05-2020)“…Dendritic cells (DCs) constitute a complex network of cell subsets with common functions but also with many divergent aspects. All dendritic cell subsets share…”
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7
The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage
Published in Blood (07-09-2017)“…CCRL2 is a 7-transmembrane domain receptor that shares structural and functional similarities with the family of atypical chemokine receptors (ACKRs). CCRL2 is…”
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8
SARS-CoV-2–associated ssRNAs activate inflammation and immunity via TLR7/8
Published in JCI insight (22-09-2021)“…The inflammatory and IFN pathways of innate immunity play a key role in the resistance and pathogenesis of coronavirus disease 2019 (COVID-19). Innate sensors…”
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9
Inhibitory receptors of plasmacytoid dendritic cells as possible targets for checkpoint blockade in cancer
Published in Frontiers in immunology (05-03-2024)“…Plasmacytoid dendritic cells (pDCs) are the major producers of type I interferons (IFNs), which are essential to mount antiviral and antitumoral immune…”
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10
Inhibition of Class I Histone Deacetylase Activity Blocks the Induction of TNFAIP3 Both Directly and Indirectly via the Suppression of Endogenous TNF-α
Published in International journal of molecular sciences (01-09-2022)“…Histone deacetylase inhibitors (HDIs) are promising drugs for the treatment of inflammatory diseases. However, their therapeutical exploitation is slowed down…”
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11
Extracellular vesicles at the crossroad between cancer progression and immunotherapy: focus on dendritic cells
Published in Journal of translational medicine (29-07-2024)“…Extracellular vesicles (EVs) are nanosized heat-stable vesicles released by virtually all cells in the body, including tumor cells and tumor-infiltrating…”
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12
Regulation of neutrophil associated RNASET2 expression in rheumatoid arthritis
Published in Scientific reports (05-11-2024)“…Neutrophils (PMNs) are key players of innate immune responses through the release of cytoplasmic granule content and the formation of neutrophil extracellular…”
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13
Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
Published in Cell communication and signaling (08-11-2024)“…The physiological relevance of cell-to-cell communication mediated by small extracellular vesicle-encapsulated microRNAs (sEV-miRNAs) remains debated because…”
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14
Z-alpha1-antitrypsin polymers and small airways disease: a new paradigm in alfa-1 anti-trypsin deficiency-related COPD development?
Published in Monaldi archives for chest disease (08-06-2021)“…The presence of Alpha1-Antitrypsin (AAT) polymers, known to promote a sustained pro-inflammatory activity, has been previously demonstrated in bronchial…”
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15
The PDE4 Inhibitor Tanimilast Blunts Proinflammatory Dendritic Cell Activation by SARS-CoV-2 ssRNAs
Published in Frontiers in immunology (24-01-2022)“…Phosphodiesterase 4 (PDE4) inhibitors are immunomodulatory drugs approved to treat diseases associated with chronic inflammatory conditions, such as COPD,…”
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16
The PDE4 Inhibitor Tanimilast Restrains the Tissue-Damaging Properties of Human Neutrophils
Published in International journal of molecular sciences (29-04-2022)“…Neutrophils, the most abundant subset of leukocytes in the blood, play a pivotal role in host response against invading pathogens. However, in respiratory…”
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17
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation
Published in Journal of translational medicine (10-05-2022)“…Tanimilast is a novel and selective inhaled inhibitor of phosphodiesterase-4 in advanced clinical development for chronic obstructive pulmonary disease (COPD)…”
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Modulation of Human Dendritic Cell Functions by Phosphodiesterase-4 Inhibitors: Potential Relevance for the Treatment of Respiratory Diseases
Published in Pharmaceutics (31-08-2023)“…Inhibitors of phosphodiesterase-4 (PDE4) are small-molecule drugs that, by increasing the intracellular levels of cAMP in immune cells, elicit a broad spectrum…”
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19
The Atypical Receptor CCRL2 (C-C Chemokine Receptor-Like 2) Does Not Act As a Decoy Receptor in Endothelial Cells
Published in Frontiers in immunology (06-10-2017)“…C-C chemokine receptor-like 2 (CCRL2) is a non-signaling seven-transmembrane domain (7-TMD) receptor related to the atypical chemokine receptor (ACKR) family…”
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20
Optimization of the Fermentation of Cantaloupe Juice by Lactobacillus casei NRRL B-442
Published in Food and bioprocess technology (01-10-2012)“…This study was carried out to optimize the fermentation pH and temperature and also the fermentation time for development of a new probiotic fermented drink…”
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