Search Results - "Tibbs, Joseph"
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Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications
Published in Micromachines (Basel) (17-03-2023)“…Nanoscale fluorescence emitters are efficient for measuring biomolecular interactions, but their utility for applications requiring single-unit observations is…”
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2
Photonic crystal-coupled enhanced steering emission: A prism-free, objective-free, and metal-free loss-less approach for biosensing
Published in Applied physics letters (15-04-2024)“…Diagnostic assays utilizing fluorescent reporters in the context of low abundance biomarkers for cancer and infectious disease can reach lower limits of…”
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3
Label-Free Digital Detection of Intact Virions by Enhanced Scattering Microscopy
Published in Journal of the American Chemical Society (02-02-2022)“…Several applications in health diagnostics, food, safety, and environmental monitoring require rapid, simple, selective, and quantitatively accurate viral load…”
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4
A photonic resonator interferometric scattering microscope for label-free detection of nanometer-scale objects with digital precision in point-of-use environments
Published in Biosensors & bioelectronics (15-05-2023)“…Label-free detection and digital counting of nanometer-scaled objects such as nanoparticles, viruses, extracellular vesicles, and protein molecules enable a…”
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5
Dynamics and selective remodeling of the DNA-binding domains of RPA
Published in Nature structural & molecular biology (01-02-2019)“…Replication protein A (RPA) coordinates important DNA metabolic events by stabilizing single-stranded DNA (ssDNA) intermediates, activating the DNA-damage…”
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6
Photonic‐Plasmonic Coupling Enhanced Fluorescence Enabling Digital‐Resolution Ultrasensitive Protein Detection
Published in Small (Weinheim an der Bergstrasse, Germany) (01-11-2023)“…Assays utilizing fluorophores are common throughout life science research and diagnostics, although detection limits are generally limited by weak emission…”
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7
Effects of Intercalating Molecules on the Polymer Properties of DNA
Published in The journal of physical chemistry. B (17-09-2020)“…Atomic force microscopy (AFM) enables determination of physical properties from single DNA molecules. Insertion of aromatic molecules into the structure of DNA…”
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Photonic‐Plasmonic Coupling Enhanced Fluorescence Enabling Digital‐Resolution Ultrasensitive Protein Detection (Small 44/2023)
Published in Small (Weinheim an der Bergstrasse, Germany) (01-11-2023)“…Digital‐Resolution Ultrasensitive Protein Detection The synergistic coupling between a plasmonic nanostructure and a photonic crystal resonator enables a…”
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9
Detailed Balance Broken by Catch Bond Kinetics Enables Mechanical‐Adaptation in Active Materials
Published in Advanced functional materials (01-03-2021)“…Unlike nearly all engineered materials which contain bonds that weaken under load, biological materials contain “catch” bonds which are reinforced under load…”
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10
Atomic Force Microscopy Study of Intercalated DNA Molecules
Published in Biophysical journal (07-02-2020)Get full text
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11
A Dynamic Time Step Method in Cytoskeletal Simulations
Published in Biophysical journal (15-02-2019)Get full text
Journal Article -
12
Effects of Intercalating Molecules on the Polymer Properties of DNA
Published in The journal of physical chemistry. B (01-10-2020)“…Atomic force microscopy (AFM) enables determination of physical properties from single DNA molecules. Insertion of aromatic molecules into the structure of DNA…”
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Journal Article -
13
KERA: analysis tool for multi-process, multi-state single-molecule data
Published in Nucleic acids research (21-05-2021)“…Abstract Molecular machines within cells dynamically assemble, disassemble and reorganize. Molecular interactions between their components can be observed at…”
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Journal Article -
14
A Photonic Resonator Interferometric Scattering Microscope for Label-Free Imaging of Bio-Nanoparticles in Point-of-Use Environments
Published in 2024 Conference on Lasers and Electro-Optics (CLEO) (05-05-2024)“…We report a compact Photonic Resonator Interferometric Scattering Microscope for digital detection of gold nanoparticles, viruses, extracellular vesicles, and…”
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Conference Proceeding -
15
Photonic Crystal Enhanced Fluorescence Emission for Ultrasensitive Biosensing in Liquid Biopsies
Published in 2024 Conference on Lasers and Electro-Optics (CLEO) (05-05-2024)“…We present advanced biosensing methods with photonics crystal enhanced fluorescence emission from Quantum Dots, Plasmonic Fluorophores, and DNA Nano-grippers…”
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Conference Proceeding -
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Cardiovascular responses in spontaneously hypertensive rabbits
Published 01-01-1957Get full text
Dissertation