Search Results - "Tibbo, Amy J."

Phosphodiesterase 4B: Master Regulator of Brain Signaling by Tibbo, Amy J, Baillie, George S

“…Phosphodiesterases (PDEs) are the only superfamily of enzymes that have the ability to break down cyclic nucleotides and, as such, they have a pivotal role in…”
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Understanding PDE4's function in Alzheimer's disease; a target for novel therapeutic approaches by Tibbo, Amy J, Tejeda, Gonzalo S, Baillie, George S

“…Phosphodiesterases (PDEs) have long been considered as targets for the treatment of Alzheimer's disease (AD) and a substantial body of evidence suggests that…”
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MBTPS2 acts as a regulator of lipogenesis and cholesterol synthesis through SREBP signalling in prostate cancer by Tibbo, Amy J., Hartley, Andrew, Vasan, Richa, Shaw, Robin, Galbraith, Laura, Mui, Ernest, Leung, Hing Y., Ahmad, Imran

“…Background Prostate cancer is the most common cancer in men in the developed world, with most deaths caused by advanced and metastatic disease which has no…”
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Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins by Tibbo, Amy J., Mika, Delphine, Dobi, Sara, Ling, Jiayue, McFall, Aisling, Tejeda, Gonzalo S., Blair, Connor, MacLeod, Ruth, MacQuaide, Niall, Gök, Caglar, Fuller, William, Smith, Brian O., Smith, Godfrey L., Vandecasteele, Grégoire, Brand, Thomas, Baillie, George S.

“…Cyclic AMP is a ubiquitous second messenger used to transduce intracellular signals from a variety of Gs-coupled receptors. Compartmentalisation of protein…”
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SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca2 by Fertig, Bracy, Ling, Jiayue, Nollet, Edgar E., Dobi, Sara, Busiau, Tara, Ishikawa, Kiyotake, Yamada, Kelly, Lee, Ahyoung, Kho, Changwon, Wills, Lauren, Tibbo, Amy J., Scott, Mark, Grant, Kirsten, Campbell, Kenneth S., Birks, Emma J., MacQuaide, Niall, Hajjar, Roger, Smith, Godfrey L., Velden, Jolanda, Baillie, George S.

“…Post‐translational modification of the myofilament protein troponin I by phosphorylation is known to trigger functional changes that support enhanced…”
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SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca 2 by Fertig, Bracy, Ling, Jiayue, Nollet, Edgar E, Dobi, Sara, Busiau, Tara, Ishikawa, Kiyotake, Yamada, Kelly, Lee, Ahyoung, Kho, Changwon, Wills, Lauren, Tibbo, Amy J, Scott, Mark, Grant, Kirsten, Campbell, Kenneth S, Birks, Emma J, MacQuaide, Niall, Hajjar, Roger, Smith, Godfrey L, van der Velden, Jolanda, Baillie, George S

“…Post translational modification of the myofilament protein troponin I by phosphorylation is known to trigger functional changes that support enhanced…”
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