Search Results - "Tianjiao, Mao"
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Dental pulp stem cell-derived exosomes revitalize salivary gland epithelial cell function in NOD mice via the GPER-mediated cAMP/PKA/CREB signaling pathway
Published in Journal of translational medicine (03-06-2023)“…Restoration of salivary gland function in Sjogren's syndrome (SS) is still a challenge. Dental pulp stem cells (DPSCs) derived exosomes had shown…”
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Self-synchronization of reinjected droplets for high-efficiency droplet pairing and merging
Published in Microsystems & nanoengineering (09-03-2023)“…Droplet merging serves as a powerful tool to add reagents to moving droplets for biological and chemical reactions. However, unsynchronized droplet pairing…”
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Network pharmacology and transcriptomics analysis reveal the mechanism of BushenHuoxue formula attenuates premature ovarian failure via modulation PI3K/AKT pathway
Published in Cellular and Molecular Biology (27-05-2024)“…This study aims to analyze the active components and mechanism of Bushen Huoxue (BSHX) formula on the autoimmune premature ovarian insufficiency (POI) by…”
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Role of estrogen receptor signaling pathway-related genes in diffuse large B-cell lymphoma and identification of key targets via integrated bioinformatics analysis and experimental validation
Published in Frontiers in oncology (29-11-2022)“…Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous malignancy. Epidemiologically, the incidence of DLBCL is higher in men, and the female sex is a…”
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Apigenin, a Single Active Component of Herbal Extract, Alleviates Xerostomia via ERα-Mediated Upregulation of AQP5 Activation
Published in Frontiers in pharmacology (21-02-2022)“…Xerostomia is a common symptom in menopausal women, suggesting the role of sex steroids in disease development. Shreds of literature had reported the potential…”
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6
Design and aligner-assisted fast fabrication of a microfluidic platform for quasi-3D cell studies on an elastic polymer
Published in Bioactive materials (01-09-2022)“…While most studies of mechanical stimulation of cells are focused on two-dimensional (2D) and three-dimensional (3D) systems, it is rare to study the effects…”
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AutoDock and molecular dynamics-based therapeutic potential prediction of flavonoids for primary Sjögren's syndrome
Published in Heliyon (15-07-2024)“…Primary Sjögren's Syndrome (pSS) is a systemic autoimmune disease that leads to reduced saliva production, primarily affecting women due to estrogen…”
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The Critical Biomarkers Identification of Insulin Signaling Involved in Initiating cAMP Signaling Mediated Salivary Secretion in Sjogren Syndrome: Transcriptome Sequencing in NOD Mice Model
Published in Biological procedures online (27-12-2022)“…Sjogren's syndrome (SS) is an autoimmune disorder characterized by the destruction of exocrine glands, resulting in dry mouth and eyes. Currently, there is no…”
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A Self-Regulated Microfluidic Device with Thermal Bubble Micropumps
Published in Micromachines (Basel) (28-09-2022)“…Currently, many microchips must rely on an external force (such as syringe pump, electro-hydrodynamic pump, and peristaltic pump, etc.) to control the solution…”
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Inhibitory effect of polysaccharides extracted from Changbai Mountain Ganoderma lucidum on periodontal inflammation
Published in Heliyon (01-02-2023)“…As the main bioactive substance of Ganoderma lucidum, Ganoderma lucidum polysaccharide (GLP) has anti-inflammatory, antibacterial, and other biological…”
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Fast Chinese calligraphic character recognition with large-scale data
Published in Multimedia tools and applications (01-09-2015)“…Chinese calligraphy draws a lot of attention for its beauty and elegance. But due to the complexity of shape and styles of calligraphic characters, it is…”
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Parallel Integral Equation Based Nonoverlapping DDM for Solving Electrically-Large Scattering Problems in Half Space
Published in IEEE access (2018)“…In this paper, a parallel nonoverlapping non-conformal domain decomposition method using combined-field integral equation is proposed for fast and accurate…”
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Digital Quantification and Ultrasensitive Detection of Single Influenza Virus Using Microgel-in-Droplet Enzyme-Linked Immunosorbent Assay
Published in Analytical chemistry (Washington) (15-10-2024)“…Detection and quantification of viral particles (VPs) facilitate both diagnostics of pathogenic viruses and quality control testing of virus-based products…”
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Critical Frequency and Critical Stretching Rate for Reorientation of Cells on a Cyclically Stretched Polymer in a Microfluidic Chip
Published in ACS applied materials & interfaces (31-03-2021)“…The ability of cells to sense and respond to mechanical signals from their surrounding microenvironments is one of the key issues in tissue engineering and…”
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A simplified yet enhanced and versatile microfluidic platform for cyclic cell stretching on an elastic polymer
Published in Biofabrication (01-10-2020)“…While the microfluidic chips for cell stretching and real-time cell observations have so far been composed of three layers, the present work reports a…”
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Interferon-γ induces salivary gland epithelial cell ferroptosis in Sjogren's syndrome via JAK/STAT1-mediated inhibition of system Xc
Published in Free radical biology & medicine (20-08-2023)“…The elevated level of interferon-γ (IFN-γ) in Sjogren's syndrome (SS) triggers salivary gland epithelial cells (SGEC) death. However, the underlying mechanisms…”
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Apigenin alleviates Sjögren’s syndrome-induced salivary gland epithelial cell ferroptosis via ERα signaling-mediated regulation of the ATF3/SLC7A1l axis
Published in International immunopharmacology (17-10-2024)“…The binding of apigenin to ESR1 inhibited ATF3 expression, thereby inhibiting 66 downstream SLC7A11 and glutathione metabolism which alleviated the occurrence…”
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An oxygen-enriched thermosensitive hydrogel for the relief of a hypoxic tumor microenvironment and enhancement of radiotherapy
Published in Biomaterials science (09-11-2021)“…The rapid proliferation of tumor cells and tortuous vasculature in solid tumors often bring about a hypoxic tumor microenvironment, which renders tumor cells…”
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CD4 T cell-secreted IFN-γ in Sjögren's syndrome induces salivary gland epithelial cell ferroptosis
Published in Biochimica et biophysica acta. Molecular basis of disease (01-04-2024)“…Sjögren's syndrome (SS) is a chronic autoimmune disease that predominantly affects exocrine glands. Previous studies have demonstrated that upregulated…”
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Rosmanol induces breast cancer cells apoptosis by regulating PI3K/AKT and STAT3/JAK2 signaling pathways
Published in Oncology letters (01-08-2021)“…Breast cancer is one of the most frequently diagnosed cancers amongst women; however, there is currently no effective treatment. Natural compounds are…”
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