Search Results - "Tian, Xiang‐Ge"

Alisma genus: Phytochemical constituents, biosynthesis, and biological activities by Feng, Lei, Liu, Tian‐Tian, Huo, Xiao‐Kui, Tian, Xiang‐Ge, Wang, Chao, Lv, Xia, Ning, Jing, Zhao, Wen‐Yu, Zhang, Bao‐Jing, Sun, Cheng‐Peng, Ma, Xiao‐Chi

“…The genus Alisma contains 11 species distributed worldwide, of which at least two species (A. orientale [Sam.] Juzep. and A. plantago‐aquatica Linn.) have been…”
Get full text

Advanced Role of Hippo Signaling in Endometrial Fibrosis: Implications for Intrauterine Adhesion by Zhu, Hai-Yan, Ge, Tian-Xiang, Pan, Yi-Bin, Zhang, Song-Ying

“…Intrauterine adhesion (IUA) is a major health problem that causes infertility, menstrual irregularities, and recurrent pregnancy losses in women…”
Get full text

Uncaria rhynchophylla Ameliorates Parkinson’s Disease by Inhibiting HSP90 Expression: Insights from Quantitative Proteomics by Lan, Yu-Long, Zhou, Jun-Jun, Liu, Jing, Huo, Xiao-Kui, Wang, Ya-Li, Liang, Jia-Hao, Zhao, Jian-Chao, Sun, Cheng-Peng, Yu, Zhen-Long, Fang, Lin-Lin, Tian, Xiang-Ge, Feng, Lei, Ning, Jing, Zhang, Bao-Jing, Wang, Chao, Zhao, Xin-Yu, Ma, Xiao-Chi

“…Background/Aims: Uncaria rhynchophylla, known as “Gou-teng”, is a traditional Chinese medicine (TCM) used to extinguish wind, clear heat, arrest convulsions,…”
Get full text

Tetracyclic triterpenoids as inhibitors of cytochrome P450 3A4 and their quantitative structure activity relationship analysis by Pan, Wei, Feng, Lei, Sun, Cheng-Peng, Tian, Xiang-Ge, Shi, Chao, Wang, Chao, Lv, Xia, Wang, Yan, Huang, Shan-Shan, Zhang, Bao-Jing, Ning, Jing, Ma, Xiao-Chi

“…The interaction between herbs and clinical drugs is one of the risk factors for adverse drug reactions. In the present study, the inhibitory effects of 47…”
Get full text

Novel protostane-type triterpenoids with inhibitory human carboxylesterase 2 activities by Zhang, Zhi-Jie, Huo, Xiao-Kui, Tian, Xiang-Ge, Feng, Lei, Ning, Jing, Zhao, Xin-Yu, Sun, Cheng-Peng, Wang, Chao, Deng, Sa, Zhang, Bao-Jing, Zhang, Hou-Li, Liu, Yong

“…The rhizomes of Alisma orientalis have been used for centuries in China and other Asian countries as an effective herbal remedy. The phytochemical…”
Get full text

Inhibition of gut bacterial β-glucuronidase by chemical components from black tea: Inhibition interactions and molecular mechanism by Sun, Cheng-Peng, Tian, Xiang-Ge, Feng, Lei, Wang, Chao, Li, Jing-Xin, Huo, Xiao-Kui, Zhao, Wen-Yu, Ning, Jing, Yu, Zhen-Long, Deng, Sa, Zhang, Bao-Jing, Lv, Xia, Hou, Jie, Ma, Xiao-Chi

“…Gut bacterial β-glucuronidase is regarded as an important molecular target for several therapeutic applications. Inhibitors of β-glucuronidase can effectively…”
Get full text

Identification of Escherichia coli β-glucuronidase inhibitors from Polygonum cuspidatum Siebold & Zucc by Li, Jing-Xin, Wang, Yu, Hao, Ying, Huo, Xiao-Kui, Sun, Cheng-Peng, Zhao, Xiao-Xia, Wang, Jin-Cheng, Zhang, Jian-Bin, Ning, Jing, Tian, Xiang-Ge, Wang, Chao, Zhao, Wen-Yu, Lv, Xia, Li, Ya-Chen, Ma, Xiao-Chi

“…Abstract Gut bacterial β-glucuronidase (GUS) can reactivate xenobiotics that exert enterohepatic circulation- triggered gastrointestinal tract toxicity. GUS…”
Get full text

Isolation of γ‑Glutamyl-Transferase Rich-Bacteria from Mouse Gut by a Near-Infrared Fluorescent Probe with Large Stokes Shift by Liu, Tao, Yan, Qiu-Long, Feng, Lei, Ma, Xiao-Chi, Tian, Xiang-Ge, Yu, Zhen-Long, Ning, Jing, Huo, Xiao-Kui, Sun, Cheng-Peng, Wang, Chao, Cui, Jing-Nan

“…Bacterial γ-glutamyltranspeptidases (γ-GT) is a well-known metabolic enzyme, which could cleave the γ-glutamyl amide bond of γ-glutamyl analogues. As a key…”
Get full text

Uncarialins A–I, Monoterpenoid Indole Alkaloids from Uncaria rhynchophylla as Natural Agonists of the 5‑HT1A Receptor by Liang, Jia-Hao, Luan, Zhi-Lin, Tian, Xiang-Ge, Zhao, Wen-Yu, Wang, Ya-Li, Sun, Cheng-Peng, Huo, Xiao-Kui, Deng, Sa, Zhang, Bao-Jing, Zhang, Zhan-Jun, Ma, Xiao-Chi

“…Nine new monoterpenoid indole alkaloids, uncarialins A–I (1–9), were isolated from Uncaria rhynchophylla as well as 14 known analogues (10–23). Their…”
Get full text

The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase by Sun, Cheng-Peng, Yan, Jian-Kun, Yi, Jing, Zhang, Xin-Yue, Yu, Zhen-Long, Huo, Xiao-Kui, Liang, Jia-Hao, Ning, Jing, Feng, Lei, Wang, Chao, Zhang, Bao-Jing, Tian, Xiang-Ge, Zhang, Lin, Ma, Xiaochi

“…β-Glucuronidase plays a vital role in the metabolism of drugs and endogenous substance. Herein, we assayed the inhibitory effects of thirty-six flavonoids…”
Get full text

ent-Abietane and Tigliane Diterpenoids from the Roots of Euphorbia fischeriana and Their Inhibitory Effects against Mycobacterium smegmatis by Wang, Chun-Jie, Yan, Qiu-Long, Ma, Yu-Fang, Sun, Cheng-Peng, Chen, Chang-Ming, Tian, Xiang-Ge, Han, Xiu-Yan, Wang, Chao, Deng, Sa, Ma, Xiao-Chi

“…An investigation on the bioactive chemical constituents of the roots of Euphorbia fischeriana has been conducted, with 21 diterpenoids obtained using various…”
Get full text

A high-affinity fluorescent probe for human uridine-disphosphate glucuronosyltransferase 1A9 function monitoring under environmental pollutant exposure by Miao, Yi-Sheng, Wang, Jia-Yue, Zhuang, Rui-Rui, Huo, Xiao-Kui, Yi, Zi-Chang, Sun, Xiao-Nan, Yu, Zhen-Long, Tian, Xiang-Ge, Ning, Jing, Feng, Lei, Ma, Xiao-Chi, Lv, Xia

“…Uridine-disphosphate glucuronosyltransferase 1A9 (UGT1A9), an important detoxification and inactivation enzyme for toxicants, regulates the exposure level of…”
Get full text

Stability of resveratrol esters with caprylic acid during simulated in vitro gastrointestinal digestion by Hu, Xiao-Pei, Yin, Fa-Wen, Zhou, Da-Yong, Xie, Hong-Kai, Zhu, Bei-Wei, Ma, Xiao-Chi, Tian, Xiang-Ge, Wang, Chao, Shahidi, Fereidoon

“…•Preparation of resveratrol esters with caprylic acid.•Hydrolysis of resveratrol esters in modeling gastrointestinal digestion.•No hydrolysis of resveratrol…”
Get full text

Highly potent non-steroidal FXR agonists protostane-type triterpenoids: Structure-activity relationship and mechanism by Luan, Zhi-Lin, Huo, Xiao-Kui, Dong, Pei-Pei, Tian, Xiang-Ge, Sun, Cheng-Peng, Lv, Xia, Feng, Lei, Ning, Jing, Wang, Chao, Zhang, Bao-Jing, Ma, Xiao-Chi

“…Farnesoid X receptor (FXR) is a key regulator in charge of bile acid synthesis, transport, and metabolism. Activation of FXR represses bile acid synthesis and…”
Get full text

Natural soluble epoxide hydrolase inhibitors from Alisma orientale and their potential mechanism with soluble epoxide hydrolase by Zhao, Wen-Yu, Zhang, Xin-Yue, Zhou, Mei-Rong, Tian, Xiang-Ge, Lv, Xia, Zhang, Hou-Li, Deng, Sa, Zhang, Bao-Jing, Sun, Cheng-Peng, Ma, Xiao-Chi

“…Inhibition of soluble epoxide hydrolase (sEH) is considered to be an effective treatment for inflammation-related diseases, and small molecules origin from…”
Get full text

Identification and Isolation of Glucosytransferases (GT) Expressed Fungi Using a Two-Photon Ratiometric Fluorescent Probe Activated by GT by Feng, Lei, Li, Ping, Hou, Jie, Cui, Yong-Lei, Tian, Xiang-Ge, Yu, Zhen-Long, Cui, Jing-Nan, Wang, Chao, Huo, Xiao-Kui, Ning, Jing, Ma, Xiao-Chi

“…As is well-known, fungi are an important biocatalysis model of glucosylation and have been widely applied for bioactive compounds glucosylation mediated by the…”
Get full text

Regioselective hydroxylation of carbendazim by mammalian cytochrome P450: A combined experimental and computational study by Lv, Xia, Li, Jing-Xin, Wang, Jia-Yue, Tian, Xiang-Ge, Feng, Lei, Sun, Cheng-Peng, Ning, Jing, Wang, Chao, Zhao, Wen-Yu, Li, Ya-Chen, Ma, Xiao-Chi

“…Carbendazim (CBZ), a broad-spectrum pesticide frequently detected in fruits and vegetables, could trigger potential toxic risks to mammals. To facilitate the…”
Get full text

Bisfischoids A and B, dimeric ent-abietane-type diterpenoids with anti-inflammatory potential from Euphorbia fischeriana Steud by Sun, Cheng-Peng, Chang, Yi-Bo, Wang, Chao, Lv, Xia, Zhou, Wei-Yu, Tian, Xiang-Ge, Zhao, Wen-Yu, Ma, Xiao-Chi

“…[Display omitted] •Rare diterpenoid dimers with nonacyclic skeleton were obtained from E. fischeriana.•Novel dimers 1 and 2 exhibited inhibitory activities…”
Get full text

Amentoflavone from Selaginella tamariscina as a potent inhibitor of gut bacterial β-glucuronidase: Inhibition kinetics and molecular dynamics stimulation by Tian, Xiang-Ge, Yan, Jian-Kun, Sun, Cheng-Peng, Li, Jing-Xin, Ning, Jing, Wang, Chao, Huo, Xiao-Kui, Zhao, Wen-Yu, Yu, Zhen-Long, Feng, Lei, Lv, Xia, Ma, Xiao-Chi

“…Gut bacterial β-glucuronidase (GUS) plays a pivotal role in the metabolism and reactivation of a vast of glucuronide conjugates of both endogenous and…”
Get full text

Alismanin A, a Triterpenoid with a C34 Skeleton from Alisma orientale as a Natural Agonist of Human Pregnane X Receptor by Wang, Chao, Huo, Xiao-Kui, Luan, Zhi-Lin, Cao, Fei, Tian, Xiang-Ge, Zhao, Xin-Yu, Sun, Cheng-Peng, Feng, Lei, Ning, Jing, Zhang, Bao-Jing, Ma, Xiao-Chi

“…Alismanin A (1), a novel aromatic triterpenoid with a C34 skeleton, was isolated from Alisma orientale together with a rearranged nor-triterpenoid (2) and a…”
Get full text