Search Results - "Tian, Taoran"

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment by Zhang, Tao, Tian, Taoran, Zhou, Ronghui, Li, Songhang, Ma, Wenjuan, Zhang, Yuxin, Liu, Nanxin, Shi, Sirong, Li, Qianshun, Xie, Xueping, Ge, Yichen, Liu, Mengting, Zhang, Qi, Lin, Shiyu, Cai, Xiaoxiao, Lin, Yunfeng

“…Although organic nanomaterials and inorganic nanoparticles possess inherent flexibility, facilitating functional modification, increased intracellular uptake…”
Get full text

Prospects and challenges of dynamic DNA nanostructures in biomedical applications by Tian, Taoran, Li, Yanjing, Lin, Yunfeng

“…The physicochemical nature of DNA allows the assembly of highly predictable structures via several fabrication strategies, which have been applied to make…”
Get full text

Bioswitchable Delivery of microRNA by Framework Nucleic Acids: Application to Bone Regeneration by Li, Songhang, Liu, Yuhao, Tian, Taoran, Zhang, Tao, Lin, Shiyu, Zhou, Mi, Zhang, Xiaolin, Lin, Yunfeng, Cai, Xiaoxiao

“…MicroRNAs (miRs) play an important role in regulating gene expression. Limited by their instabilities, miR therapeutics require delivery vehicles. Tetrahedral…”
Get full text

Anti-inflammatory activity of curcumin-loaded tetrahedral framework nucleic acids on acute gouty arthritis by Zhang, Mei, Zhang, Xiaolin, Tian, Taoran, Zhang, Qi, Wen, Yuting, Zhu, Junyao, Xiao, Dexuan, Cui, Weitong, Lin, Yunfeng

“…Gouty arthritis is a very familiar inflammatory arthritis. Controlling inflammation is the key to preventing gouty arthritis. However, colchicine, the most…”
Get full text

Tetrahedral framework nucleic acids act as antioxidants in acute kidney injury treatment by Zhang, Qi, Lin, Shiyu, Wang, Lang, Peng, Shuanglin, Tian, Taoran, Li, Songhang, Xiao, Jingang, Lin, Yunfeng

“…[Display omitted] •Effective treatment of AKI can be achieved by a novel type of antioxidant nanostructure, i.e., tFNAs.•tFNAs exhibited protective effects of…”
Get full text

Anti-inflammatory and Antioxidative Effects of Tetrahedral DNA Nanostructures via the Modulation of Macrophage Responses by Zhang, Qi, Lin, Shiyu, Shi, Sirong, Zhang, Tao, Ma, Quanquan, Tian, Taoran, Zhou, Tengfei, Cai, Xiaoxiao, Lin, Yunfeng

“…Tetrahedral DNA nanostructures (TDNs) are a new type of nanomaterials that have recently attracted attention in the field of biomedicine. However, the…”
Get full text

The fabrication of biomimetic biphasic CAN-PAC hydrogel with a seamless interfacial layer applied in osteochondral defect repair by Liao, Jinfeng, Tian, Taoran, Shi, Sirong, Xie, Xueping, Ma, Quanquan, Li, Guo, Lin, Yunfeng

“…Cartilage tissue engineering based on biomimetic scaffolds has become a rapidly developing strategy for repairing cartilage defects. In this study, a biphasic…”
Get full text

Hard tissue stability after guided bone regeneration: a comparison between digital titanium mesh and resorbable membrane by Li, Songhang, Zhao, Junyi, Xie, Yu, Tian, Taoran, Zhang, Tianxu, Cai, Xiaoxiao

“…Guided bone regeneration (GBR) uses resorbable and non-resorbable membranes as biological barriers. This study compared the differences in hard tissue…”
Get full text

Electrospun Poly(3-hydroxybutyrate-co-4-hydroxybutyrate)/Graphene Oxide Scaffold: Enhanced Properties and Promoted in Vivo Bone Repair in Rats by Zhou, Tengfei, Li, Guo, Lin, Shiyu, Tian, Taoran, Ma, Quanquan, Zhang, Qi, Shi, Sirong, Xue, Changyue, Ma, Wenjuan, Cai, Xiaoxiao, Lin, Yunfeng

“…Bone tissue engineering emerges as an advantageous technique to achieve tissue regeneration. Its scaffolds must present excellent biomechanical properties,…”
Get full text

The protective effect of tetrahedral framework nucleic acids on periodontium under inflammatory conditions by Zhou, Mi, Gao, Shaojingya, Zhang, Xiaolin, Zhang, Tianxu, Zhang, Tao, Tian, Taoran, Li, Songhang, Lin, Yunfeng, Cai, Xiaoxiao

“…Periodontitis is a common disease that causes periodontium defects and tooth loss. Controlling inflammation and tissue regeneration are two key strategies in…”
Get full text

Effects of tetrahedral framework nucleic acid/wogonin complexes on osteoarthritis by Sirong, Shi, Yang, Chen, Taoran, Tian, Songhang, Li, Shiyu, Lin, Yuxin, Zhang, Xiaoru, Shao, Tao, Zhang, Yunfeng, Lin, Xiaoxiao, Cai

“…Osteoarthritis, a disorder characterized by articular cartilage deterioration, varying degrees of inflammation, and chondrocyte apoptosis, is the most common…”
Get full text

Erythromycin loaded by tetrahedral framework nucleic acids are more antimicrobial sensitive against Escherichia coli (E. coli) by Sun, Yue, Liu, Yuhao, Zhang, Bowen, Shi, Shirong, Zhang, Tao, Zhao, Dan, Tian, Taoran, Li, Qirong, Lin, Yunfeng

“…Erythromycin is a commonly used broad-spectrum antibiotic, but resistance to this antibiotic makes its use less effective. Considerable efforts, beside finding…”
Get full text

Angiogenesis in a 3D model containing adipose tissue stem cells and endothelial cells is mediated by canonical Wnt signaling by Cai, Xiaoxiao, Xie, Jing, Yao, Yang, Cun, Xiangzhu, Lin, Shiyu, Tian, Taoran, Zhu, Bofeng, Lin, Yunfeng

“…Adipose-derived stromal cells （ASCs） have gained great attention in regenerative medicine. Progress in our understanding of adult neovascularization further…”
Get full text

Curved microstructures promote osteogenesis of mesenchymal stem cells via the RhoA/ROCK pathway by Zhang, Qi, Lin, Shiyu, Zhang, Tao, Tian, Taoran, Ma, Quanquan, Xie, Xueping, Xue, Changyue, Lin, Yunfeng, Zhu, Bofeng, Cai, Xiaoxiao

“…Objectives Cells in the osteon reside in a curved space, accordingly, the curvature of the microenvironment is an important geometric feature in bone…”
Get full text

A Novel Bioswitchable miRNA Mimic Delivery System: Therapeutic Strategies Upgraded from Tetrahedral Framework Nucleic Acid System for Fibrotic Disease Treatment and Pyroptosis Pathway Inhibition by Jiang, Yueying, Li, Songhang, Shi, Ruijianghan, Yin, Wumeng, Lv, Weitong, Tian, Taoran, Lin, Yunfeng

“…There has been considerable interest in gene vectors and their role in regulating cellular activities and treating diseases since the advent of nucleic acid…”
Get full text

A tetrahedral framework nucleic acid based multifunctional nanocapsule for tumor prophylactic mRNA vaccination by Liu, Yuhao, Li, Songhang, Lin, Shiyu, Shi, Sirong, Tian, Taoran, Zhang, Bowen, Zhang, Tao, Lin, Yunfeng

“…Synthetic antigen-encoding mRNA plays an increasingly significant role in tumor vaccine technology owing to its antigen-specific immune-activation. However,…”
Get full text

DNA framework signal amplification platform-based high-throughput systemic immune monitoring by Chen, Ye, Chen, Xingyu, Zhang, Bowen, Zhang, Yuxin, Li, Songhang, Liu, Zhiqiang, Gao, Yang, Zhao, Yuxuan, Yan, Lin, Li, Yi, Tian, Taoran, Lin, Yunfeng

“…Systemic immune monitoring is a crucial clinical tool for disease early diagnosis, prognosis and treatment planning by quantitative analysis of immune cells…”
Get full text

PCL-PEG-PCL film promotes cartilage regeneration in vivo by Fu, Na, Liao, Jinfeng, Lin, Shiyu, Sun, Ke, Tian, Taoran, Zhu, Bofeng, Lin, Yunfeng

“…Objective Management of chondral defects has long been a challenge due to poor self‐healing capacity of articular cartilage. Many approaches, ranging from…”
Get full text

Effect of substrate stiffness on proliferation and differentiation of periodontal ligament stem cells by Liu, Nanxin, Zhou, Mi, Zhang, Qi, Yong, Li, Zhang, Tao, Tian, Taoran, Ma, Quanquan, Lin, Shiyu, Zhu, Bofeng, Cai, Xiaoxiao

“…Objectives The aim of this study was to understand the effect of substrate stiffness (a mechanical factor of the extracellular matrix) on periodontal ligament…”
Get full text

A potential flower-like coating consisting of calcium-phosphate nanosheets on titanium surface by Ma, Quanquan, Liao, Jinfeng, Tian, Taoran, Zhang, Qi, Cai, Xiaoxiao

“…Titanium and its alloys have been widely used as implant materials in bio-medicine.Additionally,surface modification has been utilized to improve the chemical…”
Get full text