Search Results - "Tian, Shuoran"

Regulation of Gene Expression Associated With the N6-Methyladenosine (m6A) Enzyme System and Its Significance in Cancer by Tian, Shuoran, Lai, Junzhong, Yu, Tingting, Li, Qiumei, Chen, Qi

“…N6-methyladenosine (m6A), an important RNA modification, is a reversible behavior catalyzed by methyltransferase complexes (m6A "writers"), demethylated…”
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Therapeutic Development by Targeting the cGAS-STING Pathway in Autoimmune Disease and Cancer by Li, Qiumei, Tian, Shuoran, Liang, Jiadi, Fan, Jiqiang, Lai, Junzhong, Chen, Qi

“…DNA immune recognition regulation mediated by the cGAS-STING pathway plays an important role in immune functions. Under normal physiological conditions, cGAS…”
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Compound C Reducing Interferon Expression by Inhibiting cGAMP Accumulation by Lai, Junzhong, Luo, Xuan, Tian, Shuoran, Zhang, Xing, Huang, Shanlu, Wang, Hanze, Li, Qiumei, Cai, Shaoli, Chen, Qi

“…Cyclic GMP-AMP (cGAMP) synthase (cGAS) is a major DNA sensor responsible for cytosolic DNA-mediated innate immune response. Inhibition of cGAS may be an…”
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Stabilization of TGF‐β Receptor 1 by a Receptor‐Associated Adaptor Dictates Feedback Activation of the TGF‐β Signaling Pathway to Maintain Liver Cancer Stemness and Drug Resistance by Liu, Kewei, Tian, Fanxuan, Chen, Xu, Liu, Biyin, Tian, Shuoran, Hou, Yongying, Wang, Lei, Han, Mengyi, Peng, Shiying, Tan, Yuting, Pan, Yuwei, Chu, Zhaole, Li, Jinyang, Che, Linrong, Chen, Dongfeng, Wen, Liangzhi, Qin, Zhongyi, Li, Xianfeng, Xiang, Junyu, Bian, Xiu‐wu, Liu, Qin, Ye, Xiaoli, Wang, Tao, Wang, Bin

“…Dysregulation of the transforming growth factor‐β (TGF‐β) signaling pathway regulates cancer stem cells (CSCs) and drug sensitivity, whereas it remains largely…”
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Reduced intestinal‐to‐diffuse conversion and immunosuppressive responses underlie superiority of neoadjuvant immunochemotherapy in gastric adenocarcinoma by Wang, Lei, Wan, Linghong, Chen, Xu, Gao, Peng, Hou, Yongying, Wu, Linyu, Liu, Wenkang, Tian, Shuoran, Han, Mengyi, Peng, Shiyin, Tan, Yuting, Pan, Yuwei, Ren, Yuanfeng, Li, Jinyang, Wen, Haihui, Liu, Qin, Zhang, Mengsi, Wang, Tao, Qin, Zhong‐Yi, Xiang, Junyu, Chen, Dongfeng, Li, Xianfeng, Wang, Shu‐Nan, Chen, Chuan, Li, Mengxia, Li, Fan, Wang, Zhenning, Wang, Bin

“…Neoadjuvant immunochemotherapy (NAIC) achieves superior clinical benefits over neoadjuvant chemotherapy (NAC) in multiple types of human cancers, including…”
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Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in mice by Lai, Junzhong, Fu, Yajuan, Tian, Shuoran, Huang, Shanlu, Luo, Xuan, Lin, Lili, Zhang, Xing, Wang, Hanze, Lin, Zhang, Zhao, Heng, Lin, Shujin, Zhao, Junhong, Xu, Shan, Li, Daliang, Cai, Shaoli, Dong, Luna, Qian, Jing, Liang, Jiadi, Li, Qiumei, Zhang, Yong, Fan, Jiqiang, Balderas, Robert, Chen, Qi

“…DNA methylation abnormality is closely related to tumor occurrence and development. Chemical inhibitors targeting DNA methyltransferase (DNMTis) have been used…”
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Intestinal subtype as a biomarker of response to neoadjuvant immunochemotherapy in locally advanced gastric adenocarcinoma: insights from a prospective phase II trial by Wang, Lei, Sun, Mengting, Li, Jinyang, Wan, Linghong, Tan, Yuting, Tian, Shuoran, Hou, Yongying, Wu, Linyu, Peng, Ziyi, Hu, Xiao, Zhang, Qihua, Huang, Zening, Han, Mengyi, Peng, Shiyin, Pan, Yuwei, Ren, Yuanfeng, Zhang, Mengsi, Chen, Dongfeng, Liu, Qin, Li, Xianfeng, Qin, Zhong-yi, Xiang, Junyv, Li, Mengxia, Zhu, Jianwu, Chen, Qiyue, Luo, Huiyan, Wang, Shunan, Wang, Tao, Li, Fan, Bian, Xiu-wu, Wang, Bin

“…Purpose:Neoadjuvant immunochemotherapy (NAIC) markedly induces pathologic regression in locally advanced gastric adenocarcinoma (GAC). However, specific…”
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