Search Results - "Tian, Rui"
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1
The Toxicity and Polymorphism of β-Amyloid Oligomers
Published in International journal of molecular sciences (24-06-2020)“…It is widely accepted that β-amyloid oligomers (Aβos) play a key role in the progression of Alzheimer's disease (AD) by inducing neuron damage and cognitive…”
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The Role of α-Synuclein Oligomers in Parkinson's Disease
Published in International journal of molecular sciences (17-11-2020)“…α-synuclein (α-syn) is a protein associated with the pathogenesis of Parkinson's disease (PD), the second most common neurodegeneration disease with no…”
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3
Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death
Published in Nature communications (02-10-2020)“…Immunogenic cell death (ICD) and tumour-infiltrating T lymphocytes are severely weakened by elevated reactive oxygen species (ROS) in the tumour…”
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4
Near‐Infrared‐II Molecular Dyes for Cancer Imaging and Surgery
Published in Advanced materials (Weinheim) (01-06-2019)“…Fluorescence bioimaging affords a vital tool for both researchers and surgeons to molecularly target a variety of biological tissues and processes. This review…”
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Conductive Metal–Organic Framework Nanowire Array Electrodes for High‐Performance Solid‐State Supercapacitors
Published in Advanced functional materials (19-07-2017)“…The application of conventional metal–organic frameworks (MOFs) as electrode materials in supercapacitors is largely hindered by their conventionally poor…”
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6
Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer's disease
Published in Journal of neuroinflammation (11-06-2021)“…Tau pathology is a hallmark of Alzheimer's disease (AD) and other tauopathies. During disease progression, abnormally phosphorylated forms of tau aggregate and…”
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Activatable Fluorescence Probes for “Turn-On” and Ratiometric Biosensing and Bioimaging: From NIR‑I to NIR-II
Published in Bioconjugate chemistry (19-02-2020)“…The greatest advantage of activatable fluorescence probes (AFPs) is the inherent responsiveness to manipulate spectroscopic properties by chemical/physical…”
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Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis
Published in Nature communications (30-09-2020)“…Effectively activating macrophages against cancer is promising but challenging. In particular, cancer cells express CD47, a ‘don’t eat me’ signal that…”
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9
Design of mechanical-robust phosphorescence materials through covalent click reaction
Published in Nature communications (05-08-2023)“…It remains a great challenge to engineer materials with strong and stable interactions for the simultaneously mechanical-robust and room temperature…”
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10
Synergistic Glutathione Depletion and STING Activation to Potentiate Dendritic Cell Maturation and Cancer Vaccine Efficacy
Published in Angewandte Chemie International Edition (04-03-2024)“…Dendritic cell (DC) maturation and antigen presentation are key factors for successful vaccine‐based cancer immunotherapy. This study developed manganese‐based…”
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Selectively Regulating Lewis Acid–Base Sites in Metal–Organic Frameworks for Achieving Turn‐On/Off of the Catalytic Activity in Different CO2 Reactions
Published in Angewandte Chemie International Edition (25-04-2022)“…Regulating Lewis acid–base sites in catalysts to investigate their influence in the chemical fixation of CO2 is significant but challenging. A metal–organic…”
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12
Two-dimensional layered double hydroxide nanoadjuvant: recent progress and future direction
Published in Nanoscale (30-04-2021)“…Layered double hydroxide (LDH) is a 'sandwich'-like two-dimensional clay material that has been systematically investigated for biomedical application in the…”
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13
A Conditionally Releasable “Do not Eat Me” CD47 Signal Facilitates Microglia‐Targeted Drug Delivery for the Treatment of Alzheimer's Disease
Published in Advanced functional materials (01-06-2020)“…Efficient brain drug delivery has been a challenge in the treatment of Alzheimer's disease (AD) and other brain disorders as blood‐brain barrier (BBB) impedes…”
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14
Fast Image Interpolation via Random Forests
Published in IEEE transactions on image processing (01-10-2015)“…This paper proposes a two-stage framework for fast image interpolation via random forests (FIRF). The proposed FIRF method gives high accuracy, as well as…”
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15
G protein-coupled receptors as promising cancer targets
Published in Cancer letters (01-07-2016)“…Article Highlights • GPCR dysregulation can cause cancer, but the role of GPCRs in carcinogenesis has been largely ignored. • The latest developments suggest…”
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Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines
Published in Proceedings of the National Academy of Sciences - PNAS (03-11-2020)“…The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has highlighted the urgent need to rapidly develop therapeutic…”
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Orexin receptors: Multi-functional therapeutic targets for sleeping disorders, eating disorders, drug addiction, cancers and other physiological disorders
Published in Cellular signalling (01-12-2013)“…The orexin peptides (orexin A, orexin B) and their receptors (orexin receptor type 1, orexin receptor type 2) are involved in multiple physiological processes…”
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A genetic engineering strategy for editing near-infrared-II fluorophores
Published in Nature communications (23-05-2022)“…The second near-infrared (NIR-II) window is a fundamental modality for deep-tissue in vivo imaging. However, it is challenging to synthesize NIR-II probes with…”
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Efficient co-delivery of neo-epitopes using dispersion-stable layered double hydroxide nanoparticles for enhanced melanoma immunotherapy
Published in Biomaterials (01-08-2018)“…Cancer immunotherapy has shown tremendous progresses in recent years for various cancers and layered double hydroxide (LDH) nanoparticles are demonstrated as…”
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Immune effects of PI3K/Akt/HIF-1α-regulated glycolysis in polymorphonuclear neutrophils during sepsis
Published in Critical care (London, England) (28-01-2022)“…Effective removal of pathogenic bacteria is key to improving the prognosis of sepsis. Polymorphonuclear neutrophils (PMNs) are the most important components of…”
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