Search Results - "Tian, Lantian"
-
1
LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis
Published in BMC cancer (08-02-2021)“…Cholangiocarcinoma is a common malignant tumor of digestive system. LncRNA metallothionein 1 J, pseudogene (MT1JP) has been reported to play tumor-suppressing…”
Get full text
Journal Article -
2
Surgery After Conversion Therapy With PD-1 Inhibitors Plus Tyrosine Kinase Inhibitors Are Effective and Safe for Advanced Hepatocellular Carcinoma: A Pilot Study of Ten Patients
Published in Frontiers in oncology (19-10-2021)“…Immunotherapy with PD-1 inhibitors combined with tyrosine kinase inhibitors (TKIs) has been proven to be effective against advanced hepatocellular carcinoma…”
Get full text
Journal Article -
3
PLK1/NF-κB feedforward circuit antagonizes the mono-ADP-ribosyltransferase activity of PARP10 and facilitates HCC progression
Published in Oncogene (01-04-2020)“…Dysregulation of PARP10 has been implicated in various tumor types and plays a vital role in delaying hepatocellular carcinoma (HCC) progression. However, the…”
Get full text
Journal Article -
4
Microbial Community Profiling Distinguishes Left-Sided and Right-Sided Colon Cancer
Published in Frontiers in cellular and infection microbiology (26-11-2020)“…The difference between left- and right-sided colon cancer has become the focus of global attention, and researchers have found differences in the morbidity,…”
Get full text
Journal Article -
5
Da Vinci robot-assisted retroperitoneal tumor resection in 105 patients: a single-center experience
Published in Frontiers in oncology (23-07-2024)“…The Da Vinci Surgical System (DVSS) has the advantages of minimal invasion, rapid recovery, safety, and reliability. Although the DVSS has been widely used in…”
Get full text
Journal Article -
6
Lenvatinib plus anti-PD-1 antibodies as conversion therapy for patients with unresectable intermediate-advanced hepatocellular carcinoma: a single-arm, phase II trial
Published in Journal for immunotherapy of cancer (01-09-2023)“…Background Over 70% of the patients with hepatocellular carcinoma (HCC) are diagnosed at an advanced stage and lose the opportunity for radical surgery…”
Get full text
Journal Article -
7
In vivo and in vitro suppression of hepatocellular carcinoma by EF24, a curcumin analog
Published in PloS one (31-10-2012)“…The synthetic compound 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24) is a potent analog of curcumin that exhibits enhanced biological activity and…”
Get full text
Journal Article -
8
A Comprehensive Understanding of the Genomic Bone Tumor Landscape: A Multicenter Prospective Study
Published in Frontiers in oncology (08-06-2022)“…Complexity and heterogeneity increases the difficulty of diagnosis and treatment of bone tumors. We aimed to identify the mutational characterization and…”
Get full text
Journal Article -
9
KCNH2 regulates the growth and metastasis of pancreatic cancer
Published in Journal of Pancreatology (01-09-2023)“…Objective:. Due to the characteristics of insidious onset and early metastasis of pancreatic cancer (PC), patients are often diagnosed at an advanced stage and…”
Get full text
Journal Article -
10
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC
Published in Clinical and translational medicine (01-06-2023)“…[...]to well-studied IM, the characteristics of HBV independent integration in MO remain underexplored.3 To find the rare independent HBV integration event…”
Get full text
Journal Article -
11
PMEPA1 Stimulates the Proliferation, Colony Formation of Pancreatic Cancer Cells via the MAPK Signaling Pathway
Published in The American journal of the medical sciences (01-09-2021)“…Prostate transmembrane protein androgen-induced 1 (PMEPA1) is reportedly highly expressed in pancreatic cancer (PC). However, its biological role and…”
Get full text
Journal Article -
12
Hypoxia‐mediated sorafenib resistance can be overcome by EF24 through Von Hippel‐Lindau tumor suppressor‐dependent HIF‐1α inhibition in hepatocellular carcinoma
Published in Hepatology (Baltimore, Md.) (01-05-2013)“…The increasing incidence of hepatocellular carcinoma (HCC) is of great concern not only in the United States but throughout the world. Although sorafenib, a…”
Get full text
Journal Article -
13
Circ_0005397 inhibits ferroptosis of pancreatic cancer cells by up‐regulating PCBP2 through KAT6A/H3K9Ac
Published in The FASEB journal (15-09-2024)“…Pancreatic cancer is a highly aggressive and lethal carcinoma. Circular RNAs (circRNAs) serve key regulatory functions in pancreatic cancer. Ferroptosis was…”
Get full text
Journal Article -
14
Super Enhanced Purification of Denatured-Refolded Ubiquitinated Proteins by ThUBD Revealed Ubiquitinome Dysfunction in Liver Fibrosis
Published in Molecular & cellular proteomics (01-11-2024)“…Ubiquitination is crucial for maintaining protein homeostasis and plays a vital role in diverse biological processes. Ubiquitinome profiling and quantification…”
Get full text
Journal Article -
15
Clinicopathological characteristics of pheochromocytoma/paraganglioma and screening of prognostic markers
Published in Journal of surgical oncology (01-09-2023)“…Background Malignant pheochromocytoma/paraganglioma (PCPG) is lethal and difficult to diagnose before metastasis. This study is aiming to characterize the PCPG…”
Get full text
Journal Article -
16
Gankyrin drives metabolic reprogramming to promote tumorigenesis, metastasis and drug resistance through activating β-catenin/c-Myc signaling in human hepatocellular carcinoma
Published in Cancer letters (28-02-2019)“…Gankyrin plays important roles in tumorigenicity and metastasis of hepatocellular carcinoma (HCC). We have for the first time investigated the effects of…”
Get full text
Journal Article -
17
PLK1/NF-[kappa]B feedforward circuit antagonizes the mono-ADP-ribosyltransferase activity of PARP10 and facilitates HCC progression
Published in Oncogene (09-04-2020)“…Dysregulation of PARP10 has been implicated in various tumor types and plays a vital role in delaying hepatocellular carcinoma (HCC) progression. However, the…”
Get full text
Journal Article -
18
A phase 2 trial of the CDK4 inhibitor dalpiciclib in well-differentiated or dedifferentiated liposarcoma
Published in Journal of clinical oncology (01-06-2024)“…11547 Background: The oncogene cyclin-dependent kinase 4 (CDK4) is amplified in > 90% of well-differentiated liposarcomas (WDLS) and dedifferentiated…”
Get full text
Journal Article -
19
The expression and clinical significance of microRNA-1258 and heparanase in human breast cancer
Published in Clinical biochemistry (01-07-2013)“…To investigate the expression profile of miR-1258 and heparanase (HPSE) in breast cancer and to assess their clinicopathological significance. The expression…”
Get full text
Journal Article -
20
The difference in clinic-pathological features between signet ring cell carcinoma and gastric mucinous adenocarcinoma
Published in Tumor biology (01-10-2013)“…We investigated the clinical and pathological features as well as the prognosis of signet ring cell carcinoma (SRC) and gastric mucinous carcinoma (GMC) to lay…”
Get full text
Journal Article