Search Results - "Tian, Keli"

How Do Blended Biochemistry Classes Influence Students' Academic Performance and Perceptions of Self-Cognition? by Ren, Guijie, Zhuang, Peiyue, Guan, Xianren, Tian, Keli, Zeng, Jiping

“…The flipped classroom is becoming a popular new instructional model in higher education capable of increasing student performance in higher-order learning…”
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Downregulation of reticulocalbin‐1 differentially facilitates apoptosis and necroptosis in human prostate cancer cells by Liu, Xiaofei, Zhang, Nianzhao, Wang, Dawei, Zhu, Deyu, Yuan, Quan, Zhang, Xiulei, Qian, Lilin, Niu, Huanmin, Lu, Yi, Ren, Guijie, Tian, Keli, Yuan, Huiqing

“…Reticulocalbin 1 (RCN1), an endoplasmic reticulum (ER)‐resident Ca2+‐binding protein, is dysregulated in cancers, but its pathophysiological roles are largely…”
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Chitosan- g-poly( N-isopropylacrylamide) based nanogels for tumor extracellular targeting by Duan, Cunxian, Zhang, Dianrui, Wang, Feihu, Zheng, Dandan, Jia, Lejiao, Feng, Feifei, Liu, Yue, Wang, Yancai, Tian, Keli, Wang, Fengshan, Zhang, Qiang

“…The study presented oridonin-loaded chitosan- graft-poly( N-isopropylacrylamide) nanogels as a drug delivery system to target the tumor extracellular pH. The…”
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Reconstitution of 5′-Directed Human Mismatch Repair in a Purified System by Zhang, Yanbin, Yuan, Fenghua, Presnell, Steven R., Tian, Keli, Gao, Yin, Tomkinson, Alan E., Gu, Liya, Li, Guo-Min

“…This paper reports reconstitution of 5′-nick-directed mismatch repair using purified human proteins. The reconstituted system includes MutSα or MutSβ, MutLα,…”
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Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis by Xu, Gang, Ren, Guijie, Xu, Xia, Yuan, Huiqing, Wang, Zhenzheng, Kang, Ludong, Yu, Wenguang, Tian, Keli

“…The chemopreventive effects of curcumin and green tea catechins individually and in combination on 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis…”
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Knockdown of AGR2 induces cellular senescence in prostate cancer cells by ZHONGYI HU, YUANYUAN GU, BO HAN, JINSAN ZHANG, ZUNLING LI, KELI TIAN, YOUNG, Charles Y. F, HUIQING YUAN

“…Anterior-gradient 2 (AGR2), overexpressed in many tumors including prostate cancer (PCa), is implicated in stimulation of cell proliferation, adhesion,…”
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Diabetes promotes DMH-induced colorectal cancer by increasing the activity of glycolytic enzymes in rats by Jia, Yanglei, Xu, Gang, Zhou, Wenjing, Wang, Zhenzheng, Meng, Linlin, Zhou, Songnan, Xu, Xia, Yuan, Huiqing, Tian, Keli

“…The objective of the present study was to investigate the association between diabetes mellitus and colorectal carcinogenesis as well as the possible mechanism…”
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Induction of DNA damage and p21-dependent senescence by Riccardin D is a novel mechanism contributing to its growth suppression in prostate cancer cells in vitro and in vivo by Hu, Zhongyi, Zhang, Denglu, Hao, Jianrong, Tian, Keli, Wang, Wei, Lou, Hongxiang, Yuan, Huiqing

“…Purpose Our previous studies had shown that Riccardin D (RD) exhibited cytotoxic effects by induction of apoptosis and inhibition of angiogenesis and…”
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Riccardin D Exerts Its Antitumor Activity by Inducing DNA Damage in PC-3 Prostate Cancer Cells In Vitro and In Vivo by Hu, Zhongyi, Kong, Feng, Si, Manfei, Tian, Keli, Yu, Lin Xi, Young, Charles Y F, Yuan, Huiqing, Lou, Hongxiang

“…We recently reported that Riccardin D (RD) was able to induce apoptosis by targeting Topo II. Here, we found that RD induced cell cycle arrest in G2/M phase in…”
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Oxidative stress induced autophagy in cancer associated fibroblast enhances proliferation and metabolism of colorectal cancer cells by Zhou, Wenjing, Xu, Gang, Wang, Yunqiu, Xu, Ziao, Liu, Xiaofei, Xu, Xia, Ren, Guijie, Tian, Keli

“…Tumors are comprised of malignant cancer cells and stromal cells which constitute the tumor microenvironment (TME). Previous studies have shown that cancer…”
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Assessment of blended biochemistry classes based on massive open online courses and a “semi‐flipped” learning environment by Ren, Guijie, Zeng, Jiping, Guan, Xianren, Zhuang, Peiyue, Zhang, Pengju, Liu, Zhifang, Tian, Keli

“…Flipped classroom based on active learning is becoming an increasingly popular pedagogical method in higher education capable of increasing student performance…”
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Hyper‐acetylation contributes to the sensitivity of chemo‐resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A by Xu, Qingqing, Liu, Xiaofei, Zhu, Shiqin, Hu, Xuelei, Niu, Huanmin, Zhang, Xiulei, Zhu, Deyu, Nesa, Effat Un, Tian, Keli, Yuan, Huiqing

“…Therapeutic agents are urgently needed for treating metastatic castration‐refractory prostate cancer (mCRPC) that is unresponsive to androgen deprivation and…”
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Pro-metastatic activity of AGR2 interrupts angiogenesis target bevacizumab efficiency via direct interaction with VEGFA and activation of NF-κB pathway by Jia, Mengqi, Guo, Yanxia, Zhu, Deyu, Zhang, Nianzhao, Li, Lin, Jiang, Jin, Dong, Yiwen, Xu, Qingqing, Zhang, Xiulei, Wang, Meijuan, Yu, Haina, Wang, Fang, Tian, Keli, Zhang, Jinsan, Young, Charles Y.F., Lou, Hongxiang, Yuan, Huiqing

“…Anterior gradient 2 (AGR2), an endoplasmic reticulum (ER)-resident protein-disulfide isomerase (PDI), is associated with cancer development and malignant…”
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Targeting the lysosome by an aminomethylated Riccardin D triggers DNA damage through cathepsin B‐mediated degradation of BRCA1 by Wang, Yanyan, Niu, Huanmin, Hu, Zhongyi, Zhu, Mengyuan, Wang, Lining, Han, Lili, Qian, Lilin, Tian, Keli, Yuan, Huiqing, Lou, Hongxiang

“…RD‐N, an aminomethylated derivative of riccardin D, is a lysosomotropic agent that can trigger lysosomal membrane permeabilization followed by cathepsin B…”
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Anti-inflammatory effect of Marchantin M contributes to sensitization of prostate cancer cells to docetaxel by Niu, Leilei, Deng, Jingti, Zhu, Fanghua, Zhou, Nan, Tian, Keli, Yuan, Huiqing, Lou, Hongxiang

“…Abstract As pro-inflammatory cytokines and chemokines contribute to the malignancy of many types of human cancer, we examined the anti-inflammatory effect of…”
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Metformin prevents DMH‐induced colorectal cancer in diabetic rats by reversing the warburg effect by Jia, Yanglei, Ma, Zengyi, Liu, Xiaofei, Zhou, Wenjing, He, Shan, Xu, Xia, Ren, Guijie, Xu, Gang, Tian, Keli

“…Epidemiologic studies have shown that the treatment of diabetics with metformin reduced the risk of cancer‐related mortality. Here, we investigated the…”
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Mismatch Recognition Protein MutSβ Does Not Hijack (CAG) Hairpin Repair in Vitro by Tian, Lei, Hou, Caixia, Tian, Keli, Holcomb, Nathaniel C., Gu, Liya, Li, Guo-Min

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Regulation of SOD2 and β-arrestin1 by interleukin-6 contributes to the increase of IGF-1R expression in docetaxel resistant prostate cancer cells by Zhang, Denglu, Cui, Yazhou, Niu, Leilei, Xu, Xia, Tian, Keli, Young, Charles Y.F., Lou, Hongxiang, Yuan, Huiqing

“…Although several mechanisms behind resistance to docetaxel in castration-refractory prostate cancer (CRPC) have been investigated, molecular determinants of…”
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Acidic amino acids increase fusion activity in the specific fusion domain of Newcastle disease virus fusion protein by Ren, Guijie, Zhuang, Yunlong, Tian, Keli, Li, Huiyu, Diao, Xueqin, Wang, Miaomiao, Zhou, Nan, Wang, Zhiyu

“…To explore the effects of amino acids Gln and Asn within the specific fusion domain of fusion (F) protein on the specific membrane fusion in Newcastle disease…”
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Oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line by Qi, Xiaoli, Zhang, Dianrui, Xu, Xia, Feng, Feifei, Ren, Guijie, Chu, Qianqian, Zhang, Qiang, Tian, Keli

“…Oridonin, a diterpenoid isolated from Rabdosia rubescencs, has been reported to have antitumor effects. However, low solubility has limited its clinical…”
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