Search Results - "Thys, Wannes"

LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions by Desimmie, Belete Ayele, Schrijvers, Rik, Demeulemeester, Jonas, Borrenberghs, Doortje, Weydert, Caroline, Thys, Wannes, Vets, Sofie, Van Remoortel, Barbara, Hofkens, Johan, De Rijck, Jan, Hendrix, Jelle, Bannert, Norbert, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger

“…LEDGINs are novel allosteric HIV integrase (IN) inhibitors that target the lens epithelium-derived growth factor (LEDGF)/p75 binding pocket of IN. They block…”
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Correction to: LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions by Desimmie, Belete Ayele, Schrijvers, Rik, Demeulemeester, Jonas, Borrenberghs, Doortje, Weydert, Caroline, Thys, Wannes, Vets, Sofie, Van Remoortel, Barbara, Hofkens, Johan, De Rijck, Jan, Hendrix, Jelle, Bannert, Norbert, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger

“…An amendment to this paper has been published and can be accessed via the original article…”
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Arabidopsis thaliana plant defensin AtPDF1.1 is involved in the plant response to biotic stress by De Coninck, Barbara M.A, Sels, Jan, Venmans, Esther, Thys, Wannes, Goderis, Inge J.W.M, Carron, Delphine, Delauré, Stijn L, Cammue, Bruno P.A, De Bolle, Miguel F.C, Mathys, Janick

“…Previously, it was shown that the Arabidopsis thaliana plant defensins AtPDF1.1 (At1g75830) and AtPDF1.2a (At5g44420) exert in vitro antimicrobial properties…”
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A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication by Serrao, Erik, Thys, Wannes, Demeulemeester, Jonas, Al-Mawsawi, Laith Q, Christ, Frauke, Debyser, Zeger, Neamati, Nouri

“…HIV-1 integrase (IN) is an important target for contemporary antiretroviral drug design research. Historically, efforts at inactivating the enzyme have focused…”
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Interplay between HIV entry and transportin-SR2 dependency by Thys, Wannes, De Houwer, Stéphanie, Demeulemeester, Jonas, Taltynov, Oliver, Vancraenenbroeck, Renée, Gérard, Melanie, De Rijck, Jan, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger

“…Transportin-SR2 (TRN-SR2, TNPO3, transportin 3) was previously identified as an interaction partner of human immunodeficiency virus type 1 (HIV-1) integrase…”
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The HIV-1 Integrase Mutant R263A/K264A Is 2-fold Defective for TRN-SR2 Binding and Viral Nuclear Import by De Houwer, Stéphanie, Demeulemeester, Jonas, Thys, Wannes, Rocha, Susana, Dirix, Lieve, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger

“…Transportin-SR2 (Tnpo3, TRN-SR2), a human karyopherin encoded by the TNPO3 gene, has been identified as a cellular cofactor of HIV-1 replication, specifically…”
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Transportin-SR2 Imports HIV into the Nucleus by Christ, Frauke, Thys, Wannes, De Rijck, Jan, Gijsbers, Rik, Albanese, Alberto, Arosio, Daniele, Emiliani, Stephane, Rain, Jean-Christophe, Benarous, Richard, Cereseto, Anna, Debyser, Zeger

“…The human immunodeficiency virus type 1 (HIV-1) and other lentiviruses have the capacity to infect nondividing cells like macrophages. This requires import of…”
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Identification of Residues in the C-terminal Domain of HIV-1 Integrase That Mediate Binding to the Transportin-SR2 Protein by De Houwer, Stephanie, Demeulemeester, Jonas, Thys, Wannes, Taltynov, Oliver, Zmajkovicova, Katarina, Christ, Frauke, Debyser, Zeger

“…Transportin-SR2 (TRN-SR2 and TNPO3) is a cellular cofactor of HIV replication that has been implicated in the nuclear import of HIV. TRN-SR2 was originally…”
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HIV Virions as Nanoscopic Test Tubes for Probing Oligomerization of the Integrase Enzyme by Borrenberghs, Doortje, Thys, Wannes, Rocha, Susana, Demeulemeester, Jonas, Weydert, Caroline, Dedecker, Peter, Hofkens, Johan, Debyser, Zeger, Hendrix, Jelle

“…Employing viruses as nanoscopic lipid-enveloped test tubes allows the miniaturization of protein–protein interaction (PPI) assays while preserving the…”
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464 EFFICACY AND SAFETY OF SPORE-FORMING PROBIOTICS IN FUNCTIONAL DYSPEPSIA: A RANDOMIZED PLACEBO-CONTROLLED TRIAL by Wauters, Lucas, Ceulemans, Matthias, Geboers, Karlien, Toth, Joran, Thys, Wannes, Raf, Dybajlo, Daan, Walgraeve, Tack, Jan F., Vanuytsel, Tim

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Probing Protein-Protein Interactions in a Single Virus: Application to HIV Integrase Oligomerization by Borrenberghs, Doortje, thys, Wannes, Rocha, Susana, Demeulemeester, Jonas, Dedecker, Peter, Hofkens, Johan, Debyser, Zeger, Hendrix, Jelle

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Elucidating the role of Bovine Leukemia Virus encoded micro-RNAs by Durkin, Keith, Rosewick, Nicolas, Momont, Mélanie, Thys, Wannes, Burny, Arsène, Georges, Michel, Van den Broeke, Anne

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Targeting the HIV integration process in antiviral therapy by McNeely, Melissa, Christ, Frauke, Thys, Wannes, Debyser, Zeger

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Elucidating the role of Bovine Leukemia Virus encoded micro-RNAs by Durkin, Keith, Rosewick, Nicolas, Momont, Momont, Thys, Wannes, Burny, Arsène, Georges, Michel, Van den Broeke, Anne

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