Search Results - "Thynne, Tilenka"

Developments in diabetes management for older people 1991–2023 by Thynne, Tilenka R. J.

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Limitations of randomised controlled trials as evidence of drug safety by Thynne, Tilenka Rj, Gabb, Genevieve M

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Effectiveness of Interventions to Deprescribe Inappropriate Proton Pump Inhibitors in Older Adults by Wilsdon, Tom D., Hendrix, Ivanka, Thynne, Tilenka R. J., Mangoni, Arduino A.

“…Background The use of proton pump inhibitors (PPIs) in older adults is high, often inappropriate, and may cause harm. Deprescribing is defined as the…”
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Continuous Subcutaneous Hydrocortisone Infusion Therapy in Addison's Disease: A Randomized, Placebo-Controlled Clinical Trial by Gagliardi, Lucia, Nenke, Marni A, Thynne, Tilenka R. J, von der Borch, Jenny, Rankin, Wayne A, Henley, David E, Sorbello, Jane, Inder, Warrick J, Torpy, David J

“…Context: Patients with Addison's disease (AD) report impaired subjective health status (SHS). Since cortisol exhibits a robust circadian cycle that entrains…”
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Methotrexate for psoriatic arthritis by Wilsdon, Tom D, Whittle, Samuel L, Thynne, Tilenka Rj, Mangoni, Arduino A

“…Psoriatic arthritis is an inflammatory disease associated with joint damage, impaired function, pain, and reduced quality of life. Methotrexate is a…”
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Harms and benefits of sodium-glucose co-transporter 2 inhibitors by Chesterman, Thomas, Thynne, Tilenka Rj

“…Sodium-glucose co-transporter 2 inhibitors are oral glucose-lowering drugs that increase the urinary excretion of glucose. In patients with type 2 diabetes and…”
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Metformin treatment of type 2 diabetes mellitus in pregnancy: update on safety and efficacy by Polasek, Thomas M., Doogue, Matthew P., Thynne, Tilenka R.J.

“…With the increasing prevalence of type 2 diabetes mellitus (T2DM) in women of childbearing age, prescribing antidiabetic medications in first-trimester…”
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The pharmacokinetics of metformin in patients receiving intermittent haemodialysis by Sinnappah, Klarissa A., Kuan, Isabelle H.S., Thynne, Tilenka R.J., Doogue, Matthew P., Wright, Daniel F.B.

“…The aims of this study were to characterise the population pharmacokinetics of metformin in patients receiving haemodialysis, and to determine the doses that…”
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A framework for local-level economic evaluation to inform implementation decisions: health service interventions to prevent hospital-acquired hypoglycemia by Gray, Jodi, Thynne, Tilenka R, Eaton, Vaughn, Reade, Brianna, Larcombe, Rebecca, Baldacchino, Linda, Gehlert, Jessica, Hakendorf, Paul, Karnon, Jonathan

“…Published evidence on health service interventions should inform decision-making in local health services, but primary effectiveness studies and…”
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Desmopressin as a Novel Long-Term Treatment in Postural Tachycardia Syndrome Patients with Polyuria by Seeley, Marie-Claire, Thynne, Tilenka R., Braund, Wilton J, Worthley, Daniel L, Gallagher, Celine, Sanders, Prashanthan, Lau, Dennis H.

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Inappropriate prescribing and association with readmission or mortality in hospitalised older adults with frailty: a systematic review and meta-analysis by Inglis, Joshua M, Caughey, Gillian, Thynne, Tilenka, Brotherton, Kate, Liew, Danny, Mangoni, Arduino A, Shakib, Sepehr

“…Inappropriate prescribing (IP) is common in hospitalised older adults with frailty. However, it is not known whether the presence of frailty confers an…”
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Using Expert Elicitation to Adjust Published Intervention Effects to Reflect the Local Context by Gray, Jodi, Thynne, Tilenka R., Eaton, Vaughn, Larcombe, Rebecca, Tantiongco, Mahsa, Karnon, Jonathan

“…Background. Local health services make limited use of economic evaluation to inform decisions to fund new health service interventions. One barrier is the…”
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Effectiveness and safety of endothelin receptor antagonists, alone and in combination therapy, in the pulmonary arterial hypertension‐connective tissue disease subtype: A systematic review and meta‐analysis by Shivakumar, Senthuran, Thynne, Tilenka R., Mohammadi, Leila, Burdeniuk, Christine, Mangoni, Arduino A.

“…Introduction There is limited information regarding the effectiveness of endothelin receptor antagonists (ERA) in patients with connective tissue…”
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Association of Drug–Disease Interactions with Mortality or Readmission in Hospitalised Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis by Inglis, Joshua M., Caughey, Gillian, Thynne, Tilenka, Brotherton, Kate, Liew, Danny, Mangoni, Arduino A., Shakib, Sepehr

“…Background and Objective Multimorbidity is common in hospitalised adults who are at increased risk of inappropriate prescribing including drug–disease…”
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A dose of paracetamol for the levothyroxine absorption test by Thynne, Tilenka R. J., Doogue, Matthew P.

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Proton pump inhibitors and risk of readmission and mortality in older patients discharged from a tertiary hospital to residential aged care facilities by Pegoli, Matthew A., Dedigama, Maneesha, Mangoni, Arduino A., Russell, Patrick T., Grzeskowiak, Luke E., Thynne, Tilenka

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The occurrence of Hospital-Acquired Pneumonia is independently associated with elevated Stress Hyperglycaemia Ratio at admission but not elevated blood glucose by Roberts, Gregory, Chang, Leonard, Park, Joong-Min, Thynne, Tilenka

“…•What is known: Stress-induced hyperglycaemia as measured by the Stress Hyperglycaemia Ratio is associated with poor hospital outcome.•What is new: Elevated…”
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A comparison of the stress hyperglycemia ratio, glycemic gap, and glucose to assess the impact of stress‐induced hyperglycemia on ischemic stroke outcome by Roberts, Gregory, Sires, James, Chen, Angela, Thynne, Tilenka, Sullivan, Cheyne, Quinn, Stephen, Chen, Won Sun, Meyer, Emily

“…Background The aim of this study is to compare metrics specific for stress‐induced hyperglycemia (SIH) with glucose for predicting ischemic stroke outcome…”
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Prescribing of antivirals for COVID‐19 in a South Australian local health network according to statewide guidelines by Al Naji, Hiba, Inglis, Joshua M., Tucker, Emily, Rowett, Debra, Larcombe, Rebecca, Medlin, Sophie, Mangoni, Arduino A., Thynne, Tilenka

“…Antiviral drugs were rapidly implemented into clinical practice for the treatment of high‐risk patients with COVID‐19, prompting the development of statewide…”
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Therapeutic drug safety for Indigenous Australians: how do we close the gap? by Thynne, Tilenka, Gabb, Genevieve M

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