Search Results - "Thyberg, Johan"
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Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion
Published in The EMBO journal (19-05-2010)“…Amassments of heterochromatin in somatic cells occur in close contact with the nuclear envelope (NE) but are gapped by channel‐ and cone‐like zones that appear…”
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Journal Article -
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Leptin Induces Vascular Permeability and Synergistically Stimulates Angiogenesis with FGF-2 and VEGF
Published in Proceedings of the National Academy of Sciences - PNAS (22-05-2001)“…Most endocrine hormones are produced in tissues and organs with permeable microvessels that may provide an excess of hormones to be transported by the blood…”
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Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall
Published in Journal of vascular surgery (01-12-2003)“…It has been suggested that the intraluminal thrombus of abdominal aortic aneurysm (AAA) affects the underlying vessel wall. Aneurysm enlargement has been…”
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Journal Article Conference Proceeding -
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Presence of Oxidized Low Density Lipoprotein in Nonrheumatic Stenotic Aortic Valves
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-1999)“…The aim of the present study was to analyze if LDL particles trapped in stenotic aortic valve tissue undergo oxidative modification. Degenerative aortic…”
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Comparative Evaluation of FGF-2–, VEGF-A–, and VEGF-C–Induced Angiogenesis, Lymphangiogenesis, Vascular Fenestrations, and Permeability
Published in Circulation research (19-03-2004)“…ABSTRACT—Several endothelial growth factors induce both blood and lymphatic angiogenesis. However, a systematic comparative study of the impact of these…”
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Role of Microtubules in the Organization of the Golgi Complex
Published in Experimental Cell Research (01-02-1999)“…The Golgi complex of mammalian cells is composed of cisternal stacks that function in processing and sorting of membrane and luminal proteins during transport…”
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Book Review Journal Article -
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Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket
Published in Molecular biology of the cell (01-09-2004)“…The vertebrate nuclear pore complex (NPC) is a macromolecular assembly of protein subcomplexes forming a structure of eightfold radial symmetry. The NPC core…”
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Prediction of Amyloid Fibril-forming Proteins
Published in The Journal of biological chemistry (20-04-2001)“…In Alzheimer's disease and spongiform encephalopathies proteins transform from their native states into fibrils. We find that several amyloid-forming proteins…”
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Caveolae and Cholesterol Distribution in Vascular Smooth Muscle Cells of Different Phenotypes
Published in The journal of histochemistry and cytochemistry (01-02-2002)“…Vascular smooth muscle cells (SMCs) grown in primary culture are converted from a contractile to a synthetic phenotype. This includes a marked morphological…”
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Inner Nuclear Membrane Proteins Asi1, Asi2, and Asi3 Function in Concert to Maintain the Latent Properties of Transcription Factors Stp1 and Stp2
Published in The Journal of biological chemistry (05-01-2007)“…In yeast the homologous transcription factors Stp1 and Stp2 are synthesized as latent cytoplasmic precursors with N-terminal regulatory domains. In response to…”
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Differences in Caveolae Dynamics in Vascular Smooth Muscle Cells of Different Phenotypes
Published in Laboratory investigation (01-06-2000)“…Vascular smooth muscle cells shift between two major differentiated states with distinct morphological and functional properties, a contractile and a synthetic…”
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Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability
Published in Circulation (New York, N.Y.) (25-03-2003)“…Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) induces both angiogenesis and vascular permeability. Although its angiogenic…”
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Insulin-like Growth Factor II Plays a Central Role in Atherosclerosis in a Mouse Model
Published in The Journal of biological chemistry (08-02-2002)“…Insulin-like growth factor II is a fetal promoter of cell proliferation that is involved in some forms of cancer and overgrowth syndromes in humans. Here, we…”
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Phenotypic modulation of smooth muscle cells during the formation of neointimal thickenings in the rat carotid artery after balloon injury: an electron-microscopic and stereological study
Published in Cell and tissue research (01-09-1995)“…The formation of neointimal thickenings in the rat carotid artery after balloon injury was studied by a combination of electron-microscopic and stereological…”
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Microvilli structures on B lymphocytes: inducible functional domains?
Published in International immunology (01-02-2004)“…Interactive contact between B lymphocytes and T cells is necessary for their expansion during an immune response. It has been shown that B lymphocytes receive…”
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An Animal Model to Study Local Oxidation of LDL and Its Biological Effects in the Arterial Wall
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-1998)“…Oxidized LDL (oxLDL) is present in atherosclerotic lesions and is believed to play a key role in atherogenesis. Mainly on the basis of cell culture studies,…”
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Microtubules and the organization of the Golgi complex
Published in Experimental cell research (01-07-1985)“…Electron microscopic and cytochemical studies indicate that microtubules play an important role in the organization of the Golgi complex in mammalian cells…”
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Regulation of Cell Morphology in B Lymphocytes by IL-4: Evidence for Induced Cytoskeletal Changes
Published in The Journal of immunology (1950) (01-06-1998)“…Lymphocyte activation is often accompanied by changes in cell morphology, for example, in cell adhesion or motility. IL-4 is a cytokine exerting many effects…”
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Role of Tyrosine Kinases in Extracellular Matrix-Mediated Modulation of Arterial Smooth Muscle Cell Phenotype
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-1997)“…Fibronectin (FN) promotes the modulation of freshly isolated arterial smooth muscle cells (SMCs) from a contractile to a synthetic phenotype by interacting…”
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