Search Results - "Thurman, Ronald G."

Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats by Rehman, Hasibur, Krishnasamy, Yasodha, Haque, Khujista, Thurman, Ronald G, Lemasters, John J, Schnellmann, Rick G, Zhong, Zhi

“…Our previous studies showed that an extract from Camellia sinenesis (green tea), which contains several polyphenols, attenuates nephrotoxicity caused by…”
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Molecular evidence for a glycine-gated chloride channel in macrophages and leukocytes by Froh, Matthias, Thurman, Ronald G, Wheeler, Michael D

“…Recent studies have demonstrated that glycine blunts the response of Kupffer cells to endotoxin. Based on pharmacological evidence, it was hypothesized that…”
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Reduced Early Alcohol-Induced Liver Injury in CD14-Deficient Mice by Yin, Ming, Bradford, Blair U, Wheeler, Michael D, Uesugi, Takehiko, Froh, Matthias, Goyert, Sanna M, Thurman, Ronald G

“…Activation of Kupffer cells by gut-derived endotoxin is associated with alcohol-induced liver injury. Recently, it was shown that CD14-deficient mice are more…”
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In vivo lipid‐derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS by Sato, Keizo, Kadiiska, Maria B., Ghio, Andrew J., Corbett, Jean, Fann, Yang C., Holland, Steven M., Thurman, Ronald G., Mason, Ronald P.

“…Intratracheal instillation of lipopolysaccharide (LPS) activates alveolar macrophages and infiltration of neutrophils, causing lung injury/acute respiratory…”
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Role of Lipopolysaccharide-Binding Protein in Early Alcohol-Induced Liver Injury in Mice by Uesugi, Takehiko, Froh, Matthias, Arteel, Gavin E, Bradford, Blair U, Wheeler, Michael D, Gabele, Erwin, Isayama, Fuyumi, Thurman, Ronald G

“…Cellular responses to endotoxins are enhanced markedly by LPS-binding protein (LBP). Furthermore, it has been demonstrated that endotoxins and proinflammatory…”
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Dietary glycine blunts liver injury after bile duct ligation in rats by Froh, Matthias, Zhong, Zhi, Walbrun, Peter, Lehnert, Mark, Netter, Susanne, Wiest, Reiner, Conzelmann, Lars, Gabele, Erwin, Hellerbrand, Claus, Scholmerich, Jurgen, Thurman, Ronald-G

“…AIM： To investigate the effects of （dietary） glycine against oxidant-induced injury caused by bile duct ligation （BDL）. METHODS： Either a diet containing 5%…”
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Reperfusion injury after liver preservation for transplantation by Lemasters, J J, Thurman, R G

“…Preservation injury remains an obstacle to greater utilization of liver transplantation therapy. Livers can be preserved a maximum of 24 h in University of…”
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Up-regulation of CD14 in Liver Caused by Acute Ethanol Involves Oxidant-dependent AP-1 Pathway by Wheeler, Michael D, Thurman, Ronald G

“…Ethanol is known to cause both tolerance and sensitization to endotoxin (lipopolysaccharide). It is also known that ethanol modulates the expression and…”
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Kupffer Cell Sensitization by Alcohol Involves Increased Permeability to Gut-Derived Endotoxin by Enomoto, Nobuyuki, Ikejima, Kenichi, Yamashina, Shunhei, Hirose, Miyoko, Shimizu, Hidetake, Kitamura, Tsuneo, Takei, Yoshiyuki, Sato, Nobuhiro, Thurman, Ronald G.

“…Background: Studies with gut sterilization and Kupffer cell inactivation support the hypothesis that endotoxin and Kupffer cells are involved in mechanisms of…”
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Adenoviral gene delivery can inactivate Kupffer cells: role of oxidants in NF-κB activation and cytokine production by Wheeler, Michael D., Yamashina, Shunhei, Froh, Matthias, Rusyn, Ivan, Thurman, Ronald G.

“…Kupffer cells play a significant role in the pathogenesis of several liver diseases; therefore, a potential therapeutic strategy would be to inactivate the…”
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Cyclosporin A increases hypoxia and free radical production in rat kidneys: prevention by dietary glycine by Zhong, Z. (University of North Carolina, Chapel Hill.), Arteel, G.E, Connor, H.D, Yin, M, Frankenberg, M.V, Stachlewitz, R.F, Raleigh, J.A, Mason, R.P, Thurman, R.G

“…The major side effect of cyclosporin A is severe nephrotoxicity. It is likely that cyclosporin A causes vasoconstriction leading to hypoxia-reperfusion injury;…”
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Prevention of hepatic ischemia-reperfusion injury by green tea extract by Zhong, Zhi, Froh, Matthias, Connor, Henry D, Li, Xiangli, Conzelmann, Lars O, Mason, Ronald P, Lemasters, John J, Thurman, Ronald G

“…These experiments were designed to determine whether green tea extract (GTE), which contains polyphenolic free radical scavengers, prevents…”
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Heme oxygenase-1 overexpression increases liver injury after bile duct ligation in rats by Froh, Matthias, Conzelmann, Lars, Walbrun, Peter, Netter, Susanne, Wiest, Reiner, Wheeler, Michael-D, Lehnert, Mark, Uesugi, Takehiko, Scholmerich, Jurgen, Thurman, Ronald G

“…To investigate the effects of heme oxygenase-1 (HO-1) against oxidant-induced injury caused by bile duct ligation (BDL). Either cobalt protoporphyrin (CoPP), a…”
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Cocoa extract protects against early alcohol-induced liver injury in the rat by McKim, Stephen E, Konno, Akira, Gäbele, Erwin, Uesugi, Takehiko, Froh, Mathias, Sies, Helmut, Thurman, Ronald G, Arteel, Gavin E

“…Oxidants have been shown to be involved in alcohol-induced liver injury. This study was designed to determine whether cocoa flavonoid extract, composed mostly…”
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Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo by Yin, Ming, Zhong, Zhi, Connor, Henry D, Bunzendahl, Hartwig, Finn, William F, Rusyn, Ivan, Li, Xiangli, Raleigh, James A, Mason, Ronald P, Thurman, Ronald G

“…Although glycine prevents renal tubular cell injury in vitro, its effect in vivo is not clear. The purpose of this study was to investigate whether a bolus…”
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Dietary glycine inhibits the growth of B16 melanoma tumors in mice by Rose, Michelle L., Madren, Johnathan, Bunzendahl, Hartwig, Thurman, Ronald G.

“…Dietary glycine inhibited hepatocyte proliferation in response to the carcinogen WY-14,643. Since increased cell replication is associated with hepatic cancer…”
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Dietary Glycine Prevents Peptidoglycan Polysaccharide-Induced Reactive Arthritis in the Rat: Role for Glycine-Gated Chloride Channel by Li, X, Bradford, B U, Wheeler, M D, Stimpson, S A, Pink, H M, Brodie, T A, Schwab, J H, Thurman, R G

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Dietary glycine blunts lung inflammatory cell influx following acute endotoxin by Wheeler, M D, Rose, M L, Yamashima, S, Enomoto, N, Seabra, V, Madren, J, Thurman, R G

“…Mortality associated with endotoxin shock is likely mediated by Kupffer cells, alveolar macrophages, and circulating neutrophils. Acute dietary glycine…”
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Sex-related liver injury due to alcohol involves activation of Kupffer cells by endotoxin by Thurman, R G

“…Females have a greater susceptibility to ethanol-induced liver injury than males. Females who drink ethanol regularly and have been overweight for 10 years or…”
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Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice by Uesugi, Takehiko, Froh, Matthias, Arteel, Gavin E., Bradford, Blair U., Thurman, Ronald G.

“…Chronic alcohol administration increases gut-derived endotoxin in the portal blood, which activates Kupffer cells and causes liver injury. Mice (C3H/HeJ) with…”
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