Search Results - "Thuring, J W"

Identification of ARAP3, a Novel PI3K Effector Regulating Both Arf and Rho GTPases, by Selective Capture on Phosphoinositide Affinity Matrices by Krugmann, S., Anderson, K.E., Ridley, S.H., Risso, N., McGregor, A., Coadwell, J., Davidson, K., Eguinoa, A., Ellson, C.D., Lipp, P., Manifava, M., Ktistakis, N., Painter, G., Thuring, J.W., Cooper, M.A., Lim, Z.-Y., Holmes, A.B., Dove, S.K., Michell, R.H., Grewal, A., Nazarian, A., Erdjument-Bromage, H., Tempst, P., Stephens, L.R., Hawkins, P.T.

“…We show that matrices carrying the tethered homologs of natural phosphoinositides can be used to capture and display multiple phosphoinositide binding proteins…”
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FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments by Ridley, S H, Ktistakis, N, Davidson, K, Anderson, K E, Manifava, M, Ellson, C D, Lipp, P, Bootman, M, Coadwell, J, Nazarian, A, Erdjument-Bromage, H, Tempst, P, Cooper, M A, Thuring, J W, Lim, Z Y, Holmes, A B, Stephens, L R, Hawkins, P T

“…FENS-1 and DFCP1 are recently discovered proteins containing one or two FYVE-domains respectively. We show that the FYVE domains in these proteins can bind…”
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Differential Binding of Traffic-related Proteins to Phosphatidic Acid- or Phosphatidylinositol (4,5)- Bisphosphate-coupled Affinity Reagents by Manifava, Maria, Thuring, Johannes W.J.F., Lim, Ze-Yi, Packman, Len, Holmes, Andrew B., Ktistakis, Nicholas T.

“…Phosphatidic acid (PA) is an important bioactive lipid, but its molecular targets remain unknown. To identify such targets, we have synthesized and coupled PA…”
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Synthesis of strigolactones and analogs: A molecular approach to the witchweed problem by Zwanenburg, B., Thuring, J. W. J. F.

“…Abstract…”
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Crystal and molecular structure of (3aR,8bS,5'R)3-[(2,5-dihydro-3-methyl-2-oxo-5-furanyl)oxymethylene]-3,3a,4,8b-tetrahydroindeno[1,2-b]furan-2-one by MOERS, F. G, SMITS, J. M. M, BEURSKENS, P. T, THURING, J. W, ZWANENBURG, B

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PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox) by Ellson, C D, Gobert-Gosse, S, Anderson, K E, Davidson, K, Erdjument-Bromage, H, Tempst, P, Thuring, J W, Cooper, M A, Lim, Z Y, Holmes, A B, Gaffney, P R, Coadwell, J, Chilvers, E R, Hawkins, P T, Stephens, L R

“…The production of reactive oxygen species (ROS) by neutrophils has a vital role in defence against a range of infectious agents, and is driven by the assembly…”
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Ophthalmologic examination in systemic toxicity studies: an overview by Kuiper, B, Boeve, B.H, Jansen, T, Roelofs-van-Emden, M.E

“…The procedures of ophthalmologic examination used by the authors during systemic toxicity studies in laboratory animals are presented in this paper. The…”
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Cytotoxicity of menadione and related quinones in freshly isolated rat hepatocytes : effects on thiol homeostasis and energy charge by TOXOPEUS, C, VAN HOLSTEIJN, I, THURING, J. W. F, BLAAUBOER, B. J, NOORDHOEK, J

“…The cytotoxic events in freshly isolated rat hepatocytes following exposure over 2 h to menadione (2-methyl-1,4-naphthoquinone) and two closely related…”
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Non-occlusive harness for dermal toxicity studies with rabbits by Kamerman, J, Thuring, J W

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Synthesis of a Phthaloylglycine-Derived Strigol Analogue and Its Germination Stimulatory Activity toward Seeds of the Parasitic Weeds Striga hermonthica and Orobanche crenata by Nefkens, Gérard H. L, Thuring, Jan Willem J. F, Beenakkers, Marco F. M, Zwanenburg, Binne

“…The newly designed strigol analogue Nijmegen 1 (rac 7) was prepared in high overall yield starting from N-phthaloylglycine. This relatively simple analogue…”
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Asymmetric Synthesis of All Stereoisomers of the Strigol Analogue GR24. Dependence of Absolute Configuration on Stimulatory Activity of Striga hermonthica and Orobanche crenata Seed Germination by Thuring, Jan Willem J. F, Nefkens, Gerard H. L, Zwanenburg, Binne

“…All four optically pure stereoisomers of the strigol analogue GR24 were prepared via two different routes. In the first approach enantiopure ABC-fragments 4…”
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Synthesis and Biological Evaluation of the Strigol Analogue Carba-GR24 by Thuring, Jan Willem J. F., Nefkens, Gerard H. L., Zwanenburg, Binne

“…Both geometrical isomers of the strigol analogue carba-GR24,…”
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PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40 super(phox) by Ellson, C D, Gobert-Gosse, S, Anderson, KE, Davidson, K, Erdjument-Bromage, H, Tempst, P, Thuring, J W, Cooper, MA, Lim, Z-Y, Holmes, AB, Gaffney, PRJ, Coadwell, J, Chilvers, E R, Hawkins, P T, Stephens, L R

“…The production of reactive oxygen species (ROS) by neutrophils has a vital role in defence against a range of infectious agents, and is driven by the assembly…”
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Asymmetric Synthesis of All Stereoisomers of Demethylsorgolactone. Dependence of the Stimulatory Activity of Striga hermonthica and Orobanche crenata Seed Germination on the Absolute Configuration by Thuring, Jan Willem J. F, Heinsman, Nicole W. J. T, Jacobs, Robèrt W. A. W. M, Nefkens, Gérard H. L, Zwanenburg, Binne

“…Strigol and sorgolactone belong to the class of “strigolactones”, which are highly potent germination stimulants of seeds of the parasitic weeds Striga and…”
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Production and characterization of reduced NAADP (nicotinic acid-adenine dinucleotide phosphate) by Billington, Richard A, Thuring, Jan W, Conway, Stuart J, Packman, Len, Holmes, Andrew B, Genazzani, Armando A

“…The pyridine nucleotide NAADP (nicotinic acid-adenine dinucleotide phosphate) has been shown to act as a Ca2+-releasing intracellular messenger in a wide…”
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N-Phthaloylglycine-Derived Strigol Analogues. Influence of the D-Ring on Seed Germination Activity of the Parasitic Weeds Striga hermonthica and Orobanche crenata by Thuring, Jan Willem J. F, Bitter, Harry H, de Kok, Margreet M, Nefkens, Gérard H. L, van Riel, Annemiek M. D. A, Zwanenburg, Binne

“…Several strigol analogues with modifications in the D-ring were synthesized and assayed for germination stimulatory activity of seeds of Striga hermonthica and…”
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Comparative Study of the Active Site Caging of Serine Proteases:  Thrombin and Factor Xa by Thuring, Jan Willem, Li, Hui, Porter, Ned A

“…Bovine thrombin and human factor Xa were acylated at their active site selectively with inhibitors derived from the parent compound 4-guanidinophenyl…”
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Selective Inhibition, Separation, and Purification of Serine Proteases:  A Strategy Based on a Photoremovable Inhibitor by Porter, Ned. A, Thuring, Jan Willem, Li, Hui

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