Search Results - "Thuong, N.T."

A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence by GRIGORIEV, M, PRASEUTH, D, ROBIN, P, HEMAR, A, SAISON-BEHMOARAS, T, DAUTRY-VARSAT, A, THUONG, N. T, HELENE, C, HAREL-BELLAN, A

“…Oligonucleotide-directed triplex formation within upstream regulatory sequences is envisioned as a potential tool for gene inhibition. However, this approach…”
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Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides by CAZENAVE, C, STEIN, C. A, LOREAU, N, THUONG, N. T, NECKERS, L. M, SUBASINGHE, C, HELENE, C, COHEN, J. S, TOULME, J.-J

“…We have studied the translation of rabbit globin mRNA in cell free systems (reticulocyte lysate and wheat germ extract) and in microinjected Xenopus oocytes in…”
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Circular dichroism studies of an oligodeoxyribonucleotide containing a hairpin loop made of a hexaethylene glycol chain : conformation and stability by DURAND, M, CHEVRIE, K, CHASSIGNOL, M, THUONG, N. T, MAURIZOT, J. C

“…An oligodeoxyribonucleotide, d(GCTCACAAT-X-ATTGTGAGC), where X represents a hexaethylene glycol chain, was studied using circular dichroism spectroscopy. Its…”
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Site-specific intercalation at the triplex-duplex junction induces a conformational change which is detectable by hypersensitivity to diethylpyrocarbonate by COLLIER, D. A, MERGNY, J.-L, THUONG, N. T, HELENE, C

“…Using site-specific intercalation directed by intermolecular triplex formation, the conformation of an intercalation site in DNA was examined by footprinting…”
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Dynamic Mechanical Properties of Vietnam Modified Natural Rubber via Grafting with Styrene by Thuy, T. T., Nghia, P. T., Tung, N. H., Viet, D. Q., Thuong, N. T., Nhan, N. T., Dung, T. A., Kawahara, S.

“…The dynamic mechanical behavior of modified deproteinized natural rubber (DPNR) prepared by graft copolymerization with various styrene contents was…”
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Modification of DNA duplexes to smooth their thermal stability independently of their base content for DNA sequencing by hybridization by Nguyen, H.K, Auffray, P, Asseline, U, Dupret, D, Thuong, N.T

“…The possibility of equalizing DNA duplex stability is essential for the application of sequencing by hybridization. In this paper we describe a new strategy to…”
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Drug targeting: synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates by Bonfils, E., Depierreux, C., Midoux, P., Thuong, N.T., Monsigny, M., Roche, A. C.

“…Inhibition of gene expression by antisense oligonucleotides is limited by their low ability to enter cells. Knowing that sugar binding receptors, also called…”
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Psoralen-modified oligonucleotide primers improve detection of mutations by denaturing gradient gel electrophoresis and provide an alternative to GC-clamping by Costes, B, Girodon, E, Ghanem, N, Chassignol, M, Thuong, N T, Dupret, D, Goossens, M

“…Denaturing gradient gel electrophoresis (DGGE), a mutation-scanning procedure separating DNA fragments differing by as little as a single base change, is…”
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Binding of netropsin to a DNA triple helix by DURAND, M, NGUYEN THANH THUONG, MAURIZOT, J. C

“…The interaction of netropsin, a minor groove binding drug, with T-A-T triple helix and A-T double helix was studied using circular dichroism spectroscopy and…”
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Selectively 13-C enriched DNA : Evidence of fast and slow internal motions by Gaudin, F, Paquet, Françoise, Thuong, N.T, Genest, Daniel, Lancelot, G.

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Interaction of Hoechst 33258 with a DNA triple helix by Durand, M, Thuong, N T, Maurizot, J C

“…The interaction of Hoechst 33258 molecule, a minor groove binding drug, with T-A-T triple helix and A-T double helix was studied using circular dichroism…”
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An acridine-linked oligodeoxynucleotide targeted to the common 5' end of trypanosome mRNAs kills cultured parasites by Verspieren, P, Cornelissen, A W, Thuong, N T, Hélène, C, Toulmé, J J

“…Anti-messenger oligodeoxynucleotides covalently linked to an intercalating agent were tested for their ability to inhibit translation of Trypanosoma brucei…”
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Oligodeoxynucleotides covalently linked to intercalating dyes as base sequence‐specific ligands. Influence of dye attachment site by Asseline, U., Toulme, F., Thuong, N.T., Delarue, M., Montenay‐Garestier, T., Hélène, C.

“…New molecules with high and specific affinity for nucleic acid base sequences have been synthesized. They involve an oligodeoxynucleotide covalently attached…”
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Solution structure of oligonucleotides covalently linked to a psoralen derivative by Bornet, O., Prévost, C., Vovelle, F., Chassignol, M., Thuong, N.T., Lancelot, G.

“…ABSTRACT Psoralen (pso) was attached via its C-5 position to the 5'-phosphate group of an oligodeoxynucleotide d(TAAGCCG) by a hexamethylene linker (ms)…”
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Formation of a duplex structure by an a-octathymidylate: circular dichroism studies by Durand, M., Thuong, N.T., Maurizot, J.C.

“…The conformation of an octathymidylate synthesized with the α-anomer of thymidine has been studied as a function of temperature using circular dichroism. At…”
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Comparison of solution structure of free and complexed lac operator by molecular modelling with NMR constraints by Gincel, E, Lancelot, G, Maurizot, J C, Thuong, N T, Vovelle, F

“…The structure difference between the free operator of the lac system d(GCTCACAAT).d(ATTGTGAGC) and the same operator complexed to the headpiece of the lac…”
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Oligothymidylates covalently linked to an acridine derivative and with modified phosphodiester backbone: circular dichroism studies of their interactions with complementary sequences by DURAND, M, MAURIZOT, J. C, ASSELINE, U, BARBIER, C, THUONG, N. T, HELENE, C

“…Oligothymidylates involving alternating alkyl phosphotriester-phosphodiester or methylphosphonate-phosphodiester backbones and covalently linked to an acridine…”
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Oligodeoxynucleotides covalently linked to intercalating agents: a new class of gene regulatory substances by Hélène, C, Montenay-Garestier, T, Saison, T, Takasugi, M, Toulmé, J J, Asseline, U, Lancelot, G, Maurizot, J C, Toulmé, F, Thuong, N T

“…Oligodeoxynucleotides have been covalently linked to a 9-aminoacridine derivative via their 3'-phosphate group. Specific complexes are formed with the…”
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The lac repressor and its N-terminal headpiece can bind a mini-operator containing a hairpin loop made of a hexaethylene glycol chain by Maurizot, J.C., Chevrie, K., Durand, M., Thuong, N.T.

“…The binding of the lac repressor and the lac repressor N-terminal headpiece to a mini-operator with a hairpin loop made of a hexaethylene glycol chain was…”
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2D-NMR studies of the unnatural duplex α-d(TCTAAAC)-β-d(AGATTTG) by LANCELOT, G, GUESNET, J.-L, ROIG, V, THUONG, N. T

“…The unnatural oligonucleotide alpha-d(TCTAAAC) was synthesized and was found more resistant towards endonucleases than its beta-analog. 2D-NMR experiments…”
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