Search Results - "Thummel, C"

Ecdysone-regulated puff genes 2000 by Thummel, C.S.

“…The Ashburner model for the hormonal control of polytene chromosome puffing has provided a strong foundation for understanding the basic mechanisms of…”
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Molecular Mechanisms of Developmental Timing in C. elegans and Drosophila by Thummel, Carl S.

“…Characterization of the heterochronic genes has provided a strong foundation for understanding the molecular mechanisms of developmental timing in C. elegans…”
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The Ecdysone-Induced DHR4 Orphan Nuclear Receptor Coordinates Growth and Maturation in Drosophila by King-Jones, Kirst, Charles, Jean-Philippe, Lam, Geanette, Thummel, Carl S.

“…A critical determinant of insect body size is the time at which the larva stops feeding and initiates wandering in preparation for metamorphosis. No genes have…”
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A unified nomenclature system for the nuclear receptor superfamily by Auwerx, J, Baulieu, E, Beato, M, Becker-Andre, M, Burbach, PH, Camerino, G, Chambon, P, Cooney, A, Dejean, A, Dreyer, C, Evans, RM, Gannon, F, Giguere, V, Gronemeyer, H, Gustafson, JA, Laudet, V, Lazar, MA, Mangelsdorf, DJ, Milbrandt, J, Milgrom, E, Moore, DD, O'Malley, B, Parker, M, Parker, K, Perlmann, T, Pfahl, M, Rosenfeld, MG, Samuels, H, Schutz, G, Sladek, FM, Stunnenberg, HG, Spedding, M, Thummel, C, Tsai, MJ, Umesono, K, Vennstrom, B, Wahli, W, Weinberger, C, Willson, TM, Yamamoto, K

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Steroid Regulation of Postembryonic Development and Reproduction in Drosophila by Kozlova, Tatiana, Thummel, Carl S

“…Ecdysteroids trigger major developmental transitions in Drosophila, including larval molts and metamorphosis. Recent genetic studies strongly support a role…”
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Essential roles for ecdysone signaling during Drosophila mid-embryonic development by Kozlova, T, Thummel, C.S

“…Although functions for the steroid hormone ecdysone during Drosophila metamorphosis have been well established, roles for the embryonic ecdysone pulse remain…”
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Temporal Profiles of Nuclear Receptor Gene Expression Reveal Coordinate Transcriptional Responses during Drosophila Development by Sullivan, April A, Thummel, Carl S

“…The recent completion of the Drosophila genome sequence revealed 21 members of the nuclear receptor superfamily. Many of these genes are transcriptionally…”
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Mechanisms of steroid-triggered programmed cell death in Drosophila by Yin, Viravuth P., Thummel, Carl S.

“…Studies in Drosophila have provided a detailed understanding of how programmed cell death is regulated by steroid hormones during development. This work has…”
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From embryogenesis to metamorphosis: The regulation and function of drosophila nuclear receptor superfamily members by Thummel, Carl S.

“…The discovery of the nuclear receptor superfamily and detailed studies of receptor function have revolutionized our understanding of hormone action. Studies of…”
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Steroid signaling in plants and insects--common themes, different pathways by Thummel, Carl S, Chory, Joanne

“…Outside of mammals, two model systems have been the focus of intensive genetic studies aimed at defining the molecular mechanisms of steroid hormone…”
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Inducible expression of double-stranded RNA directs specific genetic interference in Drosophila by Lam, Geanette, Thummel, Carl S.

“…Background: The introduction of double-stranded RNA (dsRNA) can selectively interfere with gene expression in a wide variety of organisms, providing an ideal…”
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The Drosophila Orphan Nuclear Receptor DHR38 Mediates an Atypical Ecdysteroid Signaling Pathway by Baker, Keith D., Shewchuk, Lisa M., Kozlova, Tatiana, Makishima, Makoto, Hassell, Annie, Wisely, Bruce, Caravella, Justin A., Lambert, Millard H., Reinking, Jeffrey L., Krause, Henry, Thummel, Carl S., Willson, Timothy M., Mangelsdorf, David J.

“…Ecdysteroid pulses trigger the major developmental transitions during the Drosophila life cycle. These hormonal responses are thought to be mediated by the…”
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Temporal coordination of regulatory gene expression by the steroid hormone ecdysone by Karim, F.D, Thummel, C.S

“…In Drosophila, pulses of the steroid hormone ecdysone function as temporal signals that trigger the major postembryonic developmental transitions. The best…”
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Loss of the Ecdysteroid-Inducible E75A Orphan Nuclear Receptor Uncouples Molting from Metamorphosis in Drosophila by Bialecki, Michael, Shilton, Alycia, Fichtenberg, Caroline, Segraves, William A., Thummel, Carl S.

“…Isoform-specific null mutations were used to define the functions of three orphan members of the nuclear receptor superfamily, E75A, E75B, and E75C, encoded by…”
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Molecular Analysis of the Initiation of Insect Metamorphosis: A Comparative Study of Drosophila Ecdysteroid-Regulated Transcription by Andres, Andrew J., Fletcher, Jennifer C., Karim, Felix D., Thummel, Carl S.

“…More than 50 ecdysteroid-regulated Drosophila genes have been described in the literature. These genes were identified using several different…”
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A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis by Jiang, C, Lamblin, A F, Steller, H, Thummel, C S

“…The steroid hormone ecdysone signals the stage-specific programmed cell death of the larval salivary glands during Drosophila metamorphosis. This response is…”
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The ecdysone-inducible Broad-Complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis by Fletcher, J.C. (University of Utah, Salt Lake City, UT.), Thummel, C.S

“…Pulses of the steroid hormone ecdysone initiate Drosophila metamorphosis by inducing widespread changes in gene expression. The Broad-Complex (BR-C) and E74…”
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Vectors for Drosophila P-element-mediated transformation and tissue culture transfection by Thummel, C S, Boulet, A M, Lipshitz, H D

“…We describe nine P-element vectors that can be used to study gene regulation and function in Drosophila. These vectors were designed for use in germline…”
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Flies on steroids — Drosophila metamorphosis and the mechanisms of steroid hormone action by Thummel, Carl S.

“…Recent studies have provided new insights into the molecular mechanisms by which the steroid hormone ecdysone triggers the larval-to-adult metamoprhosis of…”
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balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila by Yin, V.P, Thummel, C.S

“…The steroid hormone ecdysone directs the massive destruction of obsolete larval tissues during Drosophila metamorphosis, providing a model system for defining…”
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