Search Results - "Thumati, Naresh R."

In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs by Hukezalie, Kyle R, Thumati, Naresh R, Côté, Hélène C F, Wong, Judy M Y

“…Telomerase is a specialized reverse transcriptase responsible for the de novo synthesis of telomeric DNA repeats. In addition to its established reverse…”
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Severity of X-linked Dyskeratosis Congenita (DKCX) Cellular Defects Is not Directly Related to Dyskerin (DKC1) Activity in Ribosomal RNA Biogenesis or mRNA Translation by Thumati, Naresh R., Zeng, Xi-Lei, Au, Hilda H. T., Jang, Christopher J., Jan, Eric, Wong, Judy M. Y.

“…ABSTRACT Dyskerin (encoded by the DKC1 locus) is the pseudouridine synthase responsible for the modification of noncoding RNA. Dyskerin is also an obligate…”
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The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita by Zeng, Xi-Lei, Thumati, Naresh R., Fleisig, Helen B., Hukezalie, Kyle R., Savage, Sharon A., Giri, Neelam, Alter, Blanche P., Wong, Judy M.Y.

“…X-linked dyskeratosis congenita (X-DC) is caused by mutations in the housekeeping nucleolar protein dyskerin. Amino acid changes associated with X-DC are…”
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Quantification of Pseudouridine Levels in Cellular RNA Pools with a Modified HPLC-UV Assay by Xu, Jialin, Gu, Alice Y, Thumati, Naresh R, Wong, Judy M Y

“…Pseudouridine (Ψ) is the most abundant post-transcriptionally modified ribonucleoside. Different Ψ modifications correlate with stress responses and are…”
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Vasodilator-Stimulated Phosphoprotein Regulates Proliferation and Growth Inhibition by Nitric Oxide in Vascular Smooth Muscle Cells by Chen, Lihua, Daum, Günter, Chitaley, Kanchan, Coats, Scott A, Bowen-Pope, Daniel F, Eigenthaler, Martin, Thumati, Naresh R, Walter, Ulrich, Clowes, Alexander W

“…OBJECTIVE—Vasodilator-stimulated phosphoprotein (VASP) was identified as a substrate for cGMP-dependent protein kinase (PKG) and cAMP-dependent protein kinase…”
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In Vitro and Ex Vivo Inhibition of Human Telomerase by Anti-HIV Nucleoside Reverse Transcriptase Inhibitors by Hukezalie, Kyle R, Thumati, Naresh R, Côté, Hélène C. F, Wong, Judy M. Y

“…Telomerase is a specialized reverse transcriptase responsible for the de novo synthesis of telomeric DNA repeats. In addition to its established reverse…”
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VASODILATOR-STIMULATED PHOSPHOPROTEIN REGULATES CELL PROLIFERATION AND GROWTH INHIBITION BY NITRIC OXIDE IN VASCULAR SMOOTH MUSCLE CELLS by Chen, Lihua, Daum, Günter, Chitaley, Kanchan, Coats, Scott A, Bowen-Pope, Daniel F, Eigenthaler, Martin, Thumati, Naresh R, Walter, Ulrich, Clowes, AlexanderW

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