Search Results - "Thull, Ulrike"

Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by McNaught, Kevin St.P., Thull, Ulrike, Carrupt, Pierre-Alain, Altomare, Cosimo, Cellamare, Saverio, Carotti, Angelo, Testa, Bernard, Jenner, Peter, Marsden, C. David

“…Isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine or 1-methyl-4-phenylpyridinium (MPP +) are inhibitors of…”
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Synthesis and Monoamine Oxidase Inhibitory Activity of New Pyridazine-, Pyrimidine- and 1,2,4-Triazine-Containing Tricyclic Derivatives by Carotti, Andrea, Catto, Marco, Leonetti, Francesco, Campagna, Francesco, Soto-Otero, Ramón, Méndez-Álvarez, Estefanía, Thull, Ulrike, Testa, Bernard, Altomare, Cosimo

“…A number of condensed azines, mostly belonging to the families of indeno-fused pyridazines (1), pyrimidines (2, 3), and 1,2,4-triazines (4, 5), were…”
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Inhibition of monoamine oxidase by isoquinoline derivatives by Thull, Ulrike, Kneubühler, Silvia, Gaillard, Patrick, Carrupt, Pierre-Alain, Testa, Bernard, Altomare, Cosimo, Carotti, Angelo, Jenner, Peter, St. P. McNaught, Kevin

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Screening of unsubstituted cyclic compounds as inhibitors of monoamine oxidases by Thull, U, Testa, B

“…A number of unsubstituted aromatic hydrocarbons, azaheterocycles, oxaheterocycles and cyclic ketones were screened for their inhibitory potency towards…”
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Inhibition of Monoamine Oxidase-B by Condensed Pyridazines and Pyrimidines:  Effects of Lipophilicity and Structure−Activity Relationships by Altomare, Cosimo, Cellamare, Saverio, Summo, Luciana, Catto, Marco, Carotti, Angelo, Thull, Ulrike, Carrupt, Pierre-Alain, Testa, Bernard, Stoeckli-Evans, Helen

“…A number of condensed pyridazines and pyrimidines were synthesized and tested for their monoamine oxidase-A (MAO-A) and MAO-B inhibitory activity. Their…”
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Natural and Synthetic Xanthones as Monoamine Oxidase Inhibitors: Biological Assay and 3D-QSAR by Gnerre, Carmela, Thull, Ulrike, Gaillard, Patrick, Carrupt, Pierre-Alain, Testa, Bernard, Fernandes, Eduarda, Silva, Francisco, Pinto, Manuela, Pinto, Madalena M. M., Wolfender, Jean-Luc, Hostettmann, Kurt, Cruciani, Gabriele

“…Fifty‐nine xanthones (=9H‐xanthen‐9‐ones) of natural or synthetic origin were investigated for their inhibitory activity toward monoamine‐oxidase A (MAO‐A) and…”
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An antifungal gamma-pyrone and xanthones with monoamine oxidase inhibitory activity from Hypericum brasiliense by Rocha, L, Marston, A, Kaplan, M A, Stoeckli-Evans, H, Thull, U, Testa, B, Hostettmann, K

“…A new gamma-pyrone (hyperbrasilone), three known xanthones (1,5-dihydroxyxanthone, 5-hydroxy-1-methoxyxanthone and 6-deoxyjacareubin) and betulinic acid have…”
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Inhibition of Monoamine Oxidase-B by 5H-Indeno[1,2-c]pyridazines: Biological Activities, Quantitative Structure-Activity Relationships (QSARs) and 3D-QSARs by Kneubuehler, Silvia, Thull, Ulrike, Altomare, Cosimo, Carta, Vincenco, Gaillard, Patrick, Carrupt, Pierre-Alain, Carotti, Angelo, Testa, Bernard

“…A large series (66 compounds) of indeno[1,2-c]pyridazin-5-ones (IPs) were synthesized and tested on their monoamine oxidase-A (MAO-A) and MAO-B inhibitory…”
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Inhibition of monoamine oxidase by isoquinoline derivatives: Qualitative and 3D-quantitative structure-activity relationships by Thull, Ulrike, Kneubühler, Silvia, Gaillard, Patrick, Carrupt, Pierre-Alain, Testa, Bernard, Altomare, Cosimo, Carotti, Angelo, Jenner, Peter, St. P. McNaught, Kevin

“…A series of isoquinolines, N-methyl-1,2-dihydroisoquinolines, N-methyl-1,2,3,4-tetrahydroisoquinolines, 1,2,3,4-tetrahydroisoquinolines, and…”
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Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP) by McNaught, Kevin ST.P., Thull, Ulrike, Carrupt, Pierre-Alain, Altomare, Cosimo, Cellamare, Saverio, Carotti, Angelo, Testa, Bernard, Jenner, Peter, Marsden, C.David

“…Mitochondrial respiratory failure secondary to complex I inhibition may contribute to the neurode-generative process underlying nigral cell death in…”
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Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration by McNaught, Kevin St.P., Thull, Ulrike, Carrupt, Pierre-Alain, Altomare, Cosimo, Cellamare, Saverio, Carotti, Angelo, Testa, Bernard, Jenner, Peter, Marsden, C.David

“…Isoquinoline derivatives exert 1-methyl-4-phenylpyridinium (MPP +)-like activity as inhibitors of complex I and α-ketoglutarate dehydrogenase activity in rat…”
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Inhibition of [ 3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by McNaught, Kevin St.P., Thull, Ulrike, Carrupt, Pierre-Alain, Altomare, Cosimo, Cellamare, Saverio, Carotti, Angelo, Testa, Bernard, Jenner, Peter, Marsden, C.David

“…Isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or 1-methyl-4-phenylpyridinium (MPP +) may be endogenous…”
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Substituted xanthones as selective and reversible monoamine oxidase A (MAO-A) inhibitors by THULL, U, KNEUBÜHLER, S, TESTA, B, BORGES, M. F. M, PINTO, M. M. M

“…1,3-Dihydroxy-2-methylxanthone (X1), its 4-chloro and 4-bromo derivatives (X1-Cl and X1-Br), and 1,3-dihydroxy-4-methylxanthone were investigated for their…”
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Inhibition of alpha-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by McNaught, K S, Altomare, C, Cellamare, S, Carotti, A, Thull, U, Carrupt, P A, Testa, B, Jenner, P, Marsden, C D

“…Defects in complex I and alpha-ketoglutarate dehydrogenase (alpha-KGDH) occur in the substantia nigra in Parkinson's disease (PD). Isoquinoline derivatives…”
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Pargyline Analogues as Potent, Non-selective Monoamine Oxidase Inhibitors by THULL, ULRIKE, CARRUPT, PIERRE-ALAIN, TESTA, BERNARD

“…2‐Methyl‐ and 2‐bromo‐3,4‐methylenedioxypargyline are novel potential monoamine oxidase (MAO) inhibitors. Their activity and MAO‐A/MAO‐B selectivity were…”
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Nigral Cell Loss Produced by Infusion of Isoquinoline Derivatives Structurally Related to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by McNaught, Kevin St.P., Thull, Ulrike, Carrupt, Pierre-Alain, Altomare, Cosimo, Cellamare, Saverio, Carotti, Angelo, Testa, Bernard, Jenner, Peter, Marsden, C.David

“…Isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6Ndash;tetrahydropyridine or 1-methyl-4-phenylpyridinium (MPP +) are potential…”
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