Search Results - "Thulasidasan, Arun Kumar T."

[6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling by Radhakrishnan, E K, Bava, Smitha V, Narayanan, Sai Shyam, Nath, Lekshmi R, Thulasidasan, Arun Kumar T, Soniya, Eppurathu Vasudevan, Anto, Ruby John

“…We report mechanism-based evidence for the anticancer and chemopreventive efficacy of [6]-gingerol, the major active principle of the medicinal plant, Ginger…”
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Evaluation of uttroside B, a saponin from Solanum nigrum Linn, as a promising chemotherapeutic agent against hepatocellular carcinoma by Nath, Lekshmi R., Gorantla, Jaggaiah N., Thulasidasan, Arun Kumar T., Vijayakurup, Vinod, Shah, Shabna, Anwer, Shabna, Joseph, Sophia M., Antony, Jayesh, Veena, Kollery Suresh, Sundaram, Sankar, Marelli, Udaya K., Lankalapalli, Ravi S., Anto, Ruby John

“…We report, for the first time, the remarkable efficacy of uttroside B, a potent saponin from Solanum nigrum Linn, against liver cancer. The compound has been…”
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Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent by Puliyappadamba, Vineshkumar T, Cheriyan, Vino T, Thulasidasan, Arun Kumar T, Bava, Smitha V, Vinod, Balachandran S, Prabhu, Priya R, Varghese, Ranji, Bevin, Arathy, Venugopal, Shalini, Anto, Ruby John

“…Lung cancer is the most lethal cancer and almost 90% of lung cancer is due to cigarette smoking. Even though nicotine, one of the major ingredients of…”
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Purely aqueous PLGA nanoparticulate formulations of curcumin exhibit enhanced anticancer activity with dependence on the combination of the carrier by Nair, K. Lekha, Thulasidasan, Arun Kumar T., Deepa, G., Anto, Ruby John, Kumar, G.S. Vinod

“…Curcumin, a yellow pigment present in turmeric, possess potential anti-proliferative and anti-inflammatory activities but poor aqueous solubility limits its…”
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Folic acid conjugation improves the bioavailability and chemosensitizing efficacy of curcumin-encapsulated PLGA-PEG nanoparticles towards paclitaxel chemotherapy by Thulasidasan, Arun Kumar T, Retnakumari, Archana P, Shankar, Mohan, Vijayakurup, Vinod, Anwar, Shabna, Thankachan, Sanu, Pillai, Kavya S, Pillai, Jisha J, Nandan, C Devika, Alex, Vijai V, Chirayil, Teena Jacob, Sundaram, Sankar, Kumar, Gopalakrishnapillai Sankaramangalam Vinod, Anto, Ruby John

“…Nanoencapsulation has emerged as a novel strategy to enhance the pharmacokinetic and therapeutic potential of conventional drugs. Recent studies from our lab…”
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Cervical cancer: A comprehensive approach towards extermination by Bava, Smitha V, Thulasidasan, Arun Kumar T, Sreekanth, Chanickal N, Anto, Ruby John

“…Human Papilloma Virus (HPV) is one of the most common sexually transmitted pathogen, globally. Oncogenic types of HPV are the causative agents of many…”
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Author Correction: Evaluation of uttroside B, a saponin from Solanum nigrum Linn, as a promising chemotherapeutic agent against hepatocellular carcinoma by Nath, Lekshmi R., Gorantla, Jaggaiah N., Thulasidasan, Arun Kumar T., Vijayakurup, Vinod, Shah, Shabna, Anwer, Shabna, Joseph, Sophia M., Antony, Jayesh, Veena, Kollery Suresh, Sundaram, Sankar, Marelli, Udaya K., Lankalapalli, Ravi S., Anto, Ruby John

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism by Bava, Smitha V., Sreekanth, Chanickal N., Thulasidasan, Arun Kumar T., Anto, Nikhil P., Cheriyan, Vino T., Puliyappadamba, Vineshkumar T., Menon, Sajna G., Ravichandran, Santhosh D., Anto, Ruby John

“…Paclitaxel is the most promising chemotherapeutic agent of plant origin despite its high cost and dose-limiting toxicity. Our earlier report has shown that…”
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Curcumin inhibits B[a]PDE-induced procarcinogenic signals in lung cancer cells, and curbs B[a]P-induced mutagenesis and lung carcinogenesis by Puliyappadamba, Vineshkumar T., Thulasidasan, Arun Kumar T, Vijayakurup, Vinod, Antony, Jayesh, Bava, Smitha V., Anwar, Shabna, Sundaram, Sankar, Anto, Ruby John

“…Benzo[a]pyrene is a procarcinogen present in environment and cigarette smoke, which could be bio‐transformed in vivo to B[a]PDE, a potent carcinogen known to…”
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Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy by Deepa, G, Thulasidasan, Arun Kumar T, Anto, Ruby John, Pillai, J Jisha, Kumar, G S Vinod

“…To investigate cross-linked hydrogels prepared via inverse emulsion polymerization to entrap poorly aqueous soluble drugs. Polyethylene glycol cross-linked…”
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Folic acid conjugated cross-linked acrylic polymer (FA-CLAP) hydrogel for site specific delivery of hydrophobic drugs to cancer cells by Pillai, Jisha Jayadevan, Thulasidasan, Arun Kumar Theralikattu, Anto, Ruby John, Chithralekha, Devika Nandan, Narayanan, Ashwanikumar, Kumar, Gopalakrishnapillai Sankaramangalam Vinod

“…The hydrogel based system is found to be rarely reported for the delivery of hydrophobic drug due to the incompatibility of hydrophilicity of the polymer…”
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Akt is upstream and MAPKs are downstream of NF-[kappa]B in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism by Bava, Smitha V, Sreekanth, Chanickal N, Thulasidasan, Arun Kumar T, Anto, Nikhil P, Cheriyan, Vino T, Puliyappadamba, Vineshkumar T, Menon, Sajna G, Ravichandran, Santhosh D, Anto, Ruby John

“…Paclitaxel is the most promising chemotherapeutic agent of plant origin despite its high cost and dose-limiting toxicity. Our earlier report has shown that…”
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