Search Results - "Thukral, Neelam"

Case Report: Respiratory lesions successfully treated with intravenous plasminogen, human-tvmh, replacement therapy in four patients with plasminogen deficiency type 1 by Nakar, Charles, McDaniel, Heather, Parker, Joseph M, Thibaudeau, Karen, Thukral, Neelam, Shapiro, Amy D

“…Plasminogen deficiency type 1 (PLGD-1, hypoplasminogenemia) is an ultra-rare, lifelong disease associated with development of fibrinous lesions in multiple…”
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Acute Airway Obstruction in 4 Pediatric Patients with Congenital Plasminogen Deficiency (C-PLGD) Treated with Intravenous Plasminogen (Human) Replacement Therapy Under an Expanded Access Protocol by Nakar, Charles, Thukral, Neelam, McDaniel, Heather L., Parker, Joseph M, Trybul, Diane, Shapiro, Amy D

“…C-PLGD is a rare autosomal recessive multisystem disorder of the fibrinolytic system. Mutations in the PLG gene result in extravascular fibrinous deposits,…”
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Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency by Shapiro, Amy D., Nakar, Charles, Parker, Joseph M., Albert, Gary R., Moran, John E., Thibaudeau, Karen, Thukral, Neelam, Hardesty, Brandon M., Laurin, Pierre, Sandset, Per Morten

“…Congenital plasminogen deficiency is caused by mutations in PLG, the gene coding for production of the zymogen plasminogen, and is an ultrarare disorder…”
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Plasminogen Eye Drops Are Effective in Preventing Recurrence of Pseudomembranes in Ligneous Conjunctivitis: Results from the Phase 2/3 KB046 Trial by Caputo, Roberto, Sartori, Maria Teresa, Leonardi, Andrea, Suffredini, Anna Lotti, Calcinai, Mirella, Crea, Roberto, Mathew, Prasad, Nakar, Charles, Thukral, Neelam, Shapiro, Amy D

“…▪ BACKGROUND Ligneous Conjunctivitis (LC) is the most common clinical manifestation of type-1 plasminogen (PLG) deficiency, a very rare autosomal recessive…”
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Treatment of Ligneous Conjunctivitis with Plasminogen Eyedrops by Caputo, Roberto, Shapiro, Amy D, Sartori, Maria Teresa, Leonardi, Andrea, Jeng, Bennie H, Nakar, Charles, Di Pasquale, Irene, Price, Jr, Francis W, Thukral, Neelam, Suffredini, Anna Lotti, Pino, Laura, Crea, Roberto, Mathew, Prasad, Calcinai, Mirella

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Safety & Efficacy of Human Plasma Derived Plasminogen Ophthalmic Drops for Treatment of Ligneous Conjunctivitis: Report of Phase 2/3 Clinical Trial by Nakar, Charles T, Caputo, Roberto, Price, Francis W, Sartori, Maria Teresa, Leonardi, Andrea, Suffredini, Anna Lotti, Thukral, Neelam, Secci, Jacopo, Jeng, Bennie H, Shapiro, Amy D

“…INTRODUCTION Plasminogen deficiency is a rare autosomal recessive disorder with variable penetrance with multisystem manifestations that may result in…”
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Pharmacokinetics, Safety, and Efficacy of Recombinant Factor VIII Fc Fusion Protein: A Practical Review by Schafer, Kim, Munn, James, Khair, Kate, Thukral, Neelam, Tom, Angela, McAlister, Sally

“…Prophylaxis for hemophilia A with conventional factor VIII (FVIII) products requires frequent intravenous dosing, which may reduce adherence. Recombinant…”
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