Search Results - "Thuillez, Christian"
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Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction
Published in Circulation (New York, N.Y.) (12-04-2016)“…BACKGROUND—The lymphatic system regulates interstitial tissue fluid balance, and lymphatic malfunction causes edema. The heart has an extensive lymphatic…”
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Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction
Published in Hypertension (Dallas, Tex. 1979) (01-04-2016)“…Mineralocorticoid receptor (MR) antagonists slow down the progression of heart failure after myocardial infarction (MI), but the cell-specific role of MR in…”
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Arterial Stiffness Is Regulated by Nitric Oxide and Endothelium-Derived Hyperpolarizing Factor During Changes in Blood Flow in Humans
Published in Hypertension (Dallas, Tex. 1979) (01-03-2010)“…Cytochrome-derived epoxyeicosatrienoic acids may be important endothelium-derived hyperpolarizing factors, opening calcium-activated potassium channels, but…”
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4
Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B‐deficient mice
Published in The FASEB journal (01-08-2014)“…The protein tyrosine phosphatase 1B (PTP1B) modulates tyrosine kinase receptors, among which is the vascular endothelial growth factor receptor type 2…”
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Role of M2-like macrophage recruitment during angiogenic growth factor therapy
Published in Angiogenesis (London) (01-04-2015)“…Therapeutic angiogenesis has yet to fulfill its promise for the clinical treatment of ischemic diseases. Given the impact of macrophages during…”
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Toll-Like Receptors 2-Deficient Mice Are Protected Against Postischemic Coronary Endothelial Dysfunction
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2007)“…OBJECTIVES—Toll-like receptors (TLR) 2 are expressed in cardiac and inflammatory cells, and regulate leukocyte function. Because leukocyte adhesion is a…”
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A sensitive LC-MS/MS method for the quantification of regioisomers of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids in human plasma during endothelial stimulation
Published in Analytical and bioanalytical chemistry (01-03-2017)“…Epoxyeicosatrienoic acids (EETs) are vasodilating lipid mediators metabolized into dihydroxyeicosatrienoic acids (DHETs) by soluble epoxide hydrolase. We aimed…”
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Arteriogenic Therapy by Intramyocardial Sustained Delivery of a Novel Growth Factor Combination Prevents Chronic Heart Failure
Published in Circulation (New York, N.Y.) (30-08-2011)“…Therapeutic angiogenesis is a promising approach for the treatment of cardiovascular diseases, including myocardial infarction and chronic heart failure. We…”
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Brachial Pressure–Independent Reduction in Carotid Stiffness After Long-Term Angiotensin-Converting Enzyme Inhibition in Diabetic Hypertensives
Published in Hypertension (Dallas, Tex. 1979) (01-07-2006)“…Hypertension and diabetes are associated with an increased arterial stiffness. A direct blood pressure–independent effect of angiotensin-converting enzyme…”
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Contribution of endothelium-derived hyperpolarizing factors to the regulation of vascular tone in humans
Published in Fundamental & clinical pharmacology (01-08-2008)“…Endothelium plays a crucial role in the regulation of cardiovascular homeostasis through the release of vasoactive factors. Besides nitric oxide (NO) and…”
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Reduction of heart failure by pharmacological inhibition or gene deletion of protein tyrosine phosphatase 1B
Published in Journal of molecular and cellular cardiology (01-06-2012)“…Abstract Protein tyrosine phosphatase 1B (PTP1B) regulates tyrosine kinase receptor-mediated responses, and especially negatively influences insulin…”
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12
Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: Prevention by the targeted antioxidant MitoQ
Published in Free radical biology & medicine (01-09-2010)“…The goal of this study was to assess mitochondrial function and ROS production in an experimental model of cocaine-induced cardiac dysfunction. We hypothesized…”
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13
Intestinal preconditioning prevents inflammatory response by modulating heme oxygenase-1 expression in endotoxic shock model
Published in American journal of physiology: Gastrointestinal and liver physiology (01-12-2007)“…Gut mucosal injury observed during ischemia-reperfusion is believed to trigger a systemic inflammatory response leading to multiple organ failure. It should be…”
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Heart Rate Reduction Induced by the If Current Inhibitor Ivabradine Improves Diastolic Function and Attenuates Cardiac Tissue Hypoxia
Published in Journal of cardiovascular pharmacology (01-03-2012)“…AIMSEnhanced heart rate (HR) is a compensatory mechanism in chronic heart failure (CHF), preserving cardiac output, but at the cost of increased left…”
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15
Coronary endothelial dysfunction after cardiomyocyte-specific mineralocorticoid receptor overexpression
Published in American journal of physiology. Heart and circulatory physiology (01-06-2011)“…The deleterious effects of aldosterone excess demonstrated in cardiovascular diseases might be linked in part to coronary vascular dysfunction. However,…”
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Clinical methods for the evaluation of endothelial function - a focus on resistance arteries
Published in Fundamental & clinical pharmacology (01-06-2006)“…Endothelial dysfunction is a key event in the pathophysiology of cardiovascular diseases and appears as a strong independent predictor of cardiovascular…”
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Transient heart rate reduction improves acute decompensated heart failure‐induced left ventricular and coronary dysfunction
Published in ESC Heart Failure (01-04-2021)“…Aims Acute decompensated heart failure (ADHF), a live‐threatening complication of heart failure (HF), associates a further decrease of the already by…”
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Improvement of peripheral endothelial dysfunction by protein tyrosine phosphatase inhibitors in heart failure
Published in Circulation (New York, N.Y.) (05-12-2006)“…Chronic heart failure (CHF) induces endothelial dysfunction characterized by a decrease in nitric oxide (NO) production in response to flow (flow-mediated…”
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Hemoglobin Camperdown [β104Arg→Ser] Detection During Hemoglobin A1c Measurement via Capillary Electrophoresis
Published in Annals of laboratory medicine (01-07-2016)“…KCI Citation Count: 0…”
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Neutral sphingomyelinase inhibition participates to the benefits of N -acetylcysteine treatment in post-myocardial infarction failing heart rats
Published in Journal of molecular and cellular cardiology (01-09-2007)“…Abstract Deficiency in cellular thiol tripeptide glutathione ( l -γ glutamyl–cysteinyl–glycine) determines the severity of several chronic and inflammatory…”
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