Search Results - "Thueson, David O"

Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents by Connor, David T, Cetenko, Wiaczeslaw A, Mullican, Michael D, Sorenson, Roderick J, Unangst, Paul C, Weikert, Robert J, Adolphson, Richard L, Kennedy, John A, Thueson, David O

“…The synthesis and antiallergic activity of a series of novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles are described. A number of the…”
Get full text

The Roles of pH and Concentration in Lactic Acid‐induced Stimulation of Epidermal Turnover by THUESON, DAVID O., CHAN, ELAINE K., OECHSLI, LAUREN M., HAHN, GARY S.

“…background. Alpha hydroxy acids such as lactic and glycolic acids (AHAs) accelerate epidermal turnover and exfoliate the stratum corneum. The roles of pH and…”
Get full text

Novel indolecarboxamidotetrazoles as potential antiallergy agents by Unangst, Paul C, Connor, David T, Stabler, S. Russell, Weikert, Robert J, Carethers, Mary E, Kennedy, John A, Thueson, David O, Chestnut, James C, Adolphson, Richard L, Conroy, M. C

“…The synthesis and antiallergic potential of a series of novel indolecarboxamidotetrazoles are described. A number of compounds inhibit the release of histamine…”
Get full text

Selective regulation of human neutrophil functions by the cell activation inhibitor CI-959 by Wright, C D, Stewart, S F, Kuipers, P J, Hoffman, M D, Devall, L J, Kennedy, J A, Ferin, M A, Thueson, D O, Conroy, M C

“…The cell activation inhibitor CI-959 [5-methoxy-3-(1-methylethoxy)-N-1H-tetrazol-5-ylbenzo[ b]thiophene-2- carboxamide, monosodium salt] was evaluated for its…”
Get more information

Novel thiophene-, pyrrole-, furan-, and benzene carboxamidotetrazoles as potential antiallergy agents by Mullican, Michael D, Sorenson, Roderick J, Connor, David T, Thueson, David O, Kennedy, John A, Conroy, Mary Carol

Get full text

Inhibition of human neutrophil activation by the allergic mediator release inhibitor, CI-949 by Wright, C D, Stewart, S F, Kuipers, P J, Hoffman, M D, Thueson, D O, Conroy, M C

“…The allergic mediator release inhibitor Cl-949 [5-methoxy-3-(1-methylethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H -indole-2-carboxamide, L-arginine salt] was…”
Get more information

Inhibition of human neutrophil activation by the allergic mediator release inhibitor, CI-922: differential inhibition of responses to a variety of stimuli by Wright, C D, Hoffman, M D, Thueson, D O, Conroy, M C

“…The allergic mediator release inhibitor 3,7-dimethoxy-4-phenyl-N-1H-tetrazol-5-yl-4H-furo[3,2-b]indole-2- carboxamide, L-arginate (CI-922) is a potent…”
Get more information

Histamine-Releasing Activity (HRA) by Thueson, David O., Speck, Linda S., Lett-Brown, Michael A., Grant, J. Andrew

“…Abstract Supernatants from 1- to 2-day cultures of human mononuclear cells induced the release of histamine from basophils. Generation of this…”
Get full text

Histamine-Releasing Activity (HRA): I. Production by Mitogen- or Antigen-Stimulated Human Mononuclear Cells by Thueson, David O, Speck, Linda S, Lett-Brown, Michael A, Grant, J. Andrew

“…Supernatants from 1- to 2-day cultures of human mononuclear cells induced the release of histamine from basophils. Generation of this histamine-releasing…”
Get full text

Novel thiophene-, pyrrole-, furan-, and benzenecarboxamidotetrazoles as potential antiallergy agents by MULLICAN, M. D, SORENSON, R. J, CONNOR, D. T, THUESON, D. O, KENNEDY, J. A, CONROY, M. C

“…The synthesis and antiallergic activity of a series of novel thiophene-, pyrrole-, furan-, and benzenecarboxamidotetrazoles are described. A number of…”
Get full text

Histamine-Releasing Activity (HRA): II. Interaction with Basophils and Physicochemical Characterization by Thueson, David O, Speck, Linda S, Lett-Brown, Michael A, Grant, J. Andrew

Get full text

Inhibition of human neutrophil activation by the allergic mediator release inhibitor, CI-922: mechanism of inhibitory activity by Wright, C D, Hoffman, M D, Thueson, D O, Conroy, M C

“…3,7-Dimethoxy-4-phenyl-N-1H tetrazol-5-yl-4H-furo[3,2-b]-indole-2- carboxamide, L-arginate (CI-922) is a potent inhibitory of human neutrophil functions in…”
Get more information

Histamine-Releasing Activity (HRA) by Thueson, David O., Speck, Linda S., Lett-Brown, Michael A., Grant, J. Andrew

“…Abstract We have recently reported the production of a histamine-releasing activity (HRA) by 1- to 2-day cultures of human mononuclear cells. Synthesis of HRA…”
Get full text

Local heat urticaria/angioedema: evidence for histamine release without complement activation by Grant, J A, Findlay, S R, Thueson, D O, Fine, D P, Krueger, G G

“…A 42-yr-old white woman reported onset in 1976 of local pruritus, burning, erythema, and edema within minutes after exposure in heat. With more extensive…”
Get more information

Histamine-releasing activity. IV. Molecular heterogeneity of the activity from stimulated human thoracic duct lymphocytes by Lett-Brown, M A, Thueson, D O, Plank, D E, Langford, M P, Grant, J A

“…Previous studies with the lymphokine, histamine-releasing activity (HRA), showed that HRA consisted of a heterogeneous group of molecules. The possibility of…”
Get more information

Histamine-releasing activity. V. Characterization and purification using high-performance liquid chromatography by Lett-Brown, M A, Thueson, D O, Plank, D E, Duffy, L, Grant, J A

“…The production of large quantities of the lymphokine(s) histamine-releasing activity (HRA) and its partial purification by Sephadex G-75 and ion-exchange…”
Get more information

Complement-mediated release of histamine from human basophils. III. Possible regulatory role of microtubules and microfilaments by Grant, J A, Dupree, E, Thueson, D O

“…The release of histamine by normal human leukocytes (basophils) following in vitro challenge with activated complement (zymosan-treated serum) was previously…”
Get more information

Diagnosis of Polistes wasp hypersensitivity by Grant, J A, Rahr, R, Thueson, D O, Lett-Brown, M A, Hokanson, J A, Yunginger, J W

“…Patients referred from the Houston, Texas, metropolitan area were evaluated for allergic reactions to insect stings. Forty-eight persons reported at least one…”
Get more information

Antigen-induced histamine release from guinea pig basophils by Lett-Brown, M A, Thueson, D O, Grant, J A

“…Guinea pig blood was found to contain an average of 106 +/- 21 ng/ml of histamine. Of this total, approximately 85-90% was of platelet origin and the rest from…”
Get more information

Effect of CI-949 and CI-959 on immune function and lymphoid organs in rats by Koller, L D, Voller, B E, Hedstrom, O R, Steppan, L G, Kerkvliet, N I, Thueson, D O

“…The immunotoxic properties of two experimental antiallergic drugs, CI-949 and CI-959, were investigated. Wistar rats were gavaged once (CI-949) or twice…”
Get more information