Search Results - "Throup, John P"

A genomic analysis of two‐component signal transduction in Streptococcus pneumoniae by Throup, John P., Koretke, Kristin K., Bryant, Alexander P., Ingraham, Karen A., Chalker, Alison F., Ge, Yigong, Marra, Andrea, Wallis, Nicola G., Brown, James R., Holmes, David J., Rosenberg, Martin, Burnham, Martin K. R.

“…A genomics‐based approach was used to identify the entire gene complement of putative two‐component signal transduction systems (TCSTSs) in Streptococcus…”
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The srhSR Gene Pair from Staphylococcus aureus:  Genomic and Proteomic Approaches to the Identification and Characterization of Gene Function by Throup, John P, Zappacosta, Francesca, Lunsford, R. Dwayne, Annan, Roland S, Carr, Steven A, Lonsdale, John T, Bryant, Alexander P, McDevitt, Damien, Rosenberg, Martin, Burnham, Martin K. R

“…Systematic analysis of the entire two-component signal transduction system (TCSTS) gene complement of Staphylococcus aureus revealed the presence of a putative…”
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SLC6A19 inhibition facilitates urinary neutral amino acid excretion and lowers plasma phenylalanine by Wobst, Heike J., Viader, Andreu, Muncipinto, Giovanni, Hollibaugh, Ryan, van Kalken, Daniel, Burkhart, Christopher T., Cantin, Susan M., Bates, Rachel M., Regimbald-Dumas, Yannik, Gross, Liam, Antalek, Mitchell T., Zweig, Joshua E., Wu, Frank, Rettenmaier, T. Justin, Labenski, Matthew T., Pullen, Nicholas, Blanchette, Heather S., Henderson, Jaclyn L., Weng, Haoling H., Vaughn, Toby A., Brown, Dean G., Throup, John P., Barrish, Joel C.

“…BACKGROUNDThe toxic accumulation of phenylalanine (Phe) in the brain underlies the neurological presentation of phenylketonuria (PKU). Solute carrier family 6…”
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Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing by Winson, Michael K, Swift, Simon, Fish, Leigh, Throup, John P, Jørgensen, Frieda, Chhabra, Siri Ram, Bycroft, Barrie W, Williams, Paul, Stewart, Gordon S.A.B

“…Plasmid reporter vectors have been constructed which respond to activation of LuxR and its homologues LasR and RhlR (VsmR) by N-acyl homoserine lactones…”
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hierarchical quorum-sensing system in Yersinia pseudotuberculosis is involved in the regulation of motility and clumping by Atkinson, S, Throup, J.P, Stewart, G.S.A.B, Williams, P

“…In cell‐free Yersinia pseudotuberculosis culture supernatants, we have chemically characterized three N‐acyl homoserine lactone (AHL) molecules, N‐octanoyl…”
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Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma by Portnoy, Alison, Kumar, Sanjay, Behm, David J, Mahar, Kelly M, Noble, Robert B, Throup, John P, Russ, Steven F

“…Urotensin II (U-II) is highly expressed in the human lung and has been implicated in regulating respiratory physiology in preclinical studies. Our objective…”
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Plants genetically modified to produce N-acylhomoserine lactones communicate with bacteria by Fray, R.G, Throup, J.P, Daykin, M, Wallace, A, Williams, P, Stewart, G.S.A.B, Grierson, D

“…N-acylhomoserine lactones (AHLs) play a critical role in plant/microbe interactions. The AHL, N-(3-oxohexanoyl)-L-homoserine lactone (OHHL), induces exoenzymes…”
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Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing by Winson, Michael K, Swift, Simon, Fish, Leigh, Throup, John P, Jørgensen, Frieda, Chhabra, Siri Ram, Bycroft, Barrie W, Williams, Paul, Stewart, Gordon S.A.B

“…Abstract Plasmid reporter vectors have been constructed which respond to activation of LuxR and its homologues LasR and RhlR (VsmR) by N-acyl homoserine…”
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Quorum sensing: a population-density component in the determination of bacterial phenotype by Swift, Simon, Throup, John P., Williams, Paul, Salmond, George P.C., Stewart, Gordon S.A.B.

“…In bacteria, a network of cellular transduction mechanisms integrate signals from the bacterial environment to control gene expression, and thereby the…”
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Characterisation of the yenI/yenR locus from Yersinia enterocolitica mediating the synthesis of two N-acylhomoserine lactone signal molecules by Throup, J P, Camara, M, Briggs, G S, Winson, M K, Chhabra, S R, Bycroft, B W, Williams, P, Stewart, G S

“…Yersinia enterocolitica produces compounds capable of transcriptionally activating the Photobacterium fischeri bioluminescence (lux) operon. Using…”
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