Discovery and applications of naturally occurring cyclic peptides
Over the last decade several families of naturally occurring cyclic peptides have been discovered that are extremely stable and have important roles as defense molecules for their host organisms. Because of their exceptional stability and potent bioactivities they can be adapted for use as scaffolds...
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| Published in: | Drug discovery today. Technologies Vol. 9; no. 1; pp. e13 - e21 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
Elsevier Ltd
2012
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| Online Access: | Get full text |
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| Summary: | Over the last decade several families of naturally occurring cyclic peptides have been discovered that are extremely stable and have important roles as defense molecules for their host organisms. Because of their exceptional stability and potent bioactivities they can be adapted for use as scaffolds in drug development. Here we describe technologies for the application of cyclic peptides in drug design. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1740-6749 1740-6749 |
| DOI: | 10.1016/j.ddtec.2011.07.005 |