Search Results - "Thorpe, Abigail L"
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Chemical Control of a CRISPR-Cas9 Acetyltransferase
Published in ACS chemical biology (16-02-2018)“…Lysine acetyltransferases (KATs) play a critical role in the regulation of transcription and other genomic functions. However, a persistent challenge is the…”
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A chemoproteomic portrait of the oncometabolite fumarate
Published in Nature chemical biology (01-04-2019)“…Hereditary cancer disorders often provide an important window into novel mechanisms supporting tumor growth. Understanding these mechanisms thus represents a…”
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A Chemical Signature for Cytidine Acetylation in RNA
Published in Journal of the American Chemical Society (10-10-2018)“…N4-acetylcytidine (ac4C) is a highly conserved modified RNA nucleobase whose formation is catalyzed by the disease-associated N-acetyltransferase 10 (NAT10)…”
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A Systems Chemoproteomic Analysis of Acyl-CoA/Protein Interaction Networks
Published in Cell chemical biology (19-03-2020)“…Acyl-coenzyme A (CoA)/protein interactions are essential for life. Despite this importance, their global scope and selectivity remains undefined. Here, we…”
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Systematic analysis of Kaposi's sarcoma (KS)‐associated herpesvirus genomes from a KS case‐control study in Cameroon: Evidence of dual infections but no association between viral sequence variation and KS risk
Published in International journal of cancer (01-10-2022)“…In sub‐Saharan Africa, Kaposi's sarcoma‐associated herpesvirus (KSHV) is endemic, and Kaposi's sarcoma (KS) is a significant public health problem. Until…”
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