Search Results - "Thornton, Paul"

Recommendations from the Pediatric Endocrine Society for Evaluation and Management of Persistent Hypoglycemia in Neonates, Infants, and Children by Thornton, Paul S., MB, BCh, Stanley, Charles A., MD, De Leon, Diva D., MD, MSCE, Harris, Deborah, PhD, Haymond, Morey W., MD, Hussain, Khalid, MD, MPH, Levitsky, Lynne L., MD, Murad, Mohammad H., MD, MPH, Rozance, Paul J., MD, Simmons, Rebecca A., MD, Sperling, Mark A., MBBS, Weinstein, David A., MD, MMSc, White, Neil H., MD, Wolfsdorf, Joseph I., MB, BCh

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Recent updates in the management of infants and children with hyperinsulinism by Thornton, Paul S.

“…To highlight recent advances in early diagnosis and the changing treatment paradigm for hyperinsulinism (HI) which can result in shorter hospitalizations,…”
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Highly Specific Dual Enzyme-Mediated Payload Release from Peptide-Coated Silica Particles by Thornton, Paul D, Heise, Andreas

“…Stimuli-responsive gate mechanisms offer potential for the controlled passage of payload molecules from a porous carrier vehicle on-demand. We describe a…”
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Approach to the Patient: Investigation of pediatric hypoglycemia in the emergency department - a practical algorithm by Thornton, Paul S, Hawkes, Colin P

“…Hypoglycemia in the pediatric population tends to present in the newborn period or during metabolic crisis triggered by prolonged fasting and intercurrent…”
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Synthesis of natural products containing the pyrrolic ring by Young, Ian S, Thornton, Paul D, Thompson, Alison

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The Production of Polysarcosine-Containing Nanoparticles by Ring-Opening Polymerization-Induced Self-Assembly by Morrell, Anna H, Warren, Nicholas J, Thornton, Paul D

“…N-carboxyanhydride ring-opening polymerization-induced self-assembly (NCA ROPISA) offers a convenient route for generating poly(amino acid)-based nanoparticles…”
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Chitosan hydrogels for targeted dye and protein adsorption by Boardman, Saskia J., Lad, Rajan, Green, David C., Thornton, Paul D.

“…ABSTRACT There is an urgent requirement to devise and develop highly‐effective materials for the purification of industrial wastewater. Colored effluents are…”
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Dasiglucagon for the Treatment of Congenital Hyperinsulinism: A Randomized Phase 3 Trial in Infants and Children by Thornton, Paul S, De Leon, Diva D, Empting, Susann, Zangen, David, Kendall, David M, Birch, Sune, Bøge, Eva, Ivkovic, Jelena, Banerjee, Indraneel

“…Abstract Context Congenital hyperinsulinism (CHI) is characterized by dysregulated insulin secretion causing hypoglycemia and consequent brain damage…”
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Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial by Thornton, Paul S, Maniatis, Aristides K, Aghajanova, Elena, Chertok, Elena, Vlachopapadopoulou, Elpis, Lin, Zhengning, Song, Wenjie, Christoffersen, Eva Dam, Breinholt, Vibeke Miller, Kovalenko, Tatiana, Giorgadze, Elene, Korpal-Szczyrska, Maria, Hofman, Paul L, Karpf, David B, Shu, Aimee D, Beckert, Michael

“…For children with growth hormone deficiency (GHD), treatment burden with daily somatropin injections [human growth hormone (hGH)] is high, which may lead to…”
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Poly(hydroxy acid) Nanoparticles for the Encapsulation and Controlled Release of Doxorubicin by Khuphe, Mthulisi, Thornton, Paul D.

“…Diblock poly(hydroxy acid) copolymers are created by the sequential ring‐opening polymerization of l‐phenylalanine O‐carboxyanhydride and…”
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Visual interpretation, not SUV ratios, is the ideal method to interpret 18F-DOPA PET scans to aid in the cure of patients with focal congenital hyperinsulinism by Garg, Pradeep K, Putegnat, Burton, Truong, Lisa, Reynolds, Courtney, Sanchez, Irene, Nedrelow, Jonathan K, Uffman, John, Lokitz, Stephen J, Nazih, Rachid, Garg, Sudha, Thornton, Paul S

“…Congenital hyperinsulinism is characterized by abnormal regulation of insulin secretion from the pancreas causing profound hypoketotic hypoglycemia and is the…”
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Block Copolypeptides Prepared by N-Carboxyanhydride Ring-Opening Polymerization by Habraken, Gijs J. M., Heise, Andreas, Thornton, Paul. D.

“…N‐Carboxyanhydride ring‐opening polymerization (NCA ROP) is a synthetically straightforward methodology to generate homopolypeptides. Extensive control over…”
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Congenital hyperinsulinism in infancy and childhood: challenges, unmet needs and the perspective of patients and families by Banerjee, Indraneel, Raskin, Julie, Arnoux, Jean-Baptiste, De Leon, Diva D, Weinzimer, Stuart A, Hammer, Mette, Kendall, David M, Thornton, Paul S

“…Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycemia in infants and children, and carries a considerable risk of neurological…”
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Hydrogen phosphate-mediated acellular biomineralisation within a dual crosslinked hyaluronic acid hydrogel by Gao, Ziyu, Hassouneh, Layla, Yang, Xuebin, Pang, Juan, Thornton, Paul D., Tronci, Giuseppe

“…[Display omitted] •Non-toxic acellular design of a dual crosslinked hyaluronic acid (HA) hydrogel•Hydrogen phosphate ions form physical crosslinks with…”
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Synthesis of a Family of Spirocyclic Scaffolds: Building Blocks for the Exploration of Chemical Space by Kumar, Sarvesh, Thornton, Paul D, Painter, Thomas O, Jain, Prashi, Downard, Jared, Douglas, Justin T, Santini, Conrad

“…This report describes the preparation of a series of 17 novel racemic spirocyclic scaffolds that are intended for the creation of compound libraries by…”
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Congenital Hyperinsulinism: An Historical Perspective by Thornton, Paul S, Stanley, Charles A, De Leon, Diva D

“…Congenital hyperinsulinism is the most common cause of persistent hypoglycemia in neonates, infants, and children. Since the first case descriptions in the…”
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An injectable, self-healing and MMP-inhibiting hyaluronic acid gel via iron coordination by Gao, Ziyu, Yang, Xuebin, Jones, Elena, Bingham, Paul A., Scrimshire, Alex, Thornton, Paul D., Tronci, Giuseppe

“…Regulating the activity of matrix metalloproteinases (MMPs) is a potential strategy for osteoarthritis (OA) therapy, although delivering this effect in a…”
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The GLOW Study does not light up the true Pediatric Endocrine Society recommendations for management of hypoglycemia in newborns by Thornton, Paul S., Rozance, Paul J., Sperling, Mark A.

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Polymer hydrogels for glutathione-mediated protein release by McAvan, Bethan S., Khuphe, Mthulisi, Thornton, Paul D.

“…[Display omitted] •Poly(S-tert-butylmercapto-l-cysteine)-terminated PEG star polymers are formed.•The copolymers are capable of self-assembly in water to form…”
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The Incidence and Etiology of Previously Undiagnosed Hypoglycemic Disorders in the Emergency Department by White, Kathryn, Truong, Lisa, Aaron, Kimberly, Mushtaq, Nasir, Thornton, Paul S

“…OBJECTIVEThe aim of this study was to determine the incidence and etiology of previously undiagnosed hypoglycemia in children (<18 years of age) seen in a…”
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