Search Results - "Thornton, M. J."

The biological actions of estrogens on skin by Thornton, M. J.

“…: There is still extensive disparity in our understanding of how estrogens exert their actions, particularly in non‐reproductive tissues such as the skin…”
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Large-scale annotation of biochemically relevant pockets and tunnels in cognate enzyme–ligand complexes by Vavra, O., Tyzack, J., Haddadi, F., Stourac, J., Damborsky, J., Mazurenko, S., Thornton, J. M., Bednar, D.

“…Tunnels in enzymes with buried active sites are key structural features allowing the entry of substrates and the release of products, thus contributing to the…”
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Senile hair graying: H₂O₂-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair by Wood, J.M, Decker, H, Hartmann, H, Chavan, B, Rokos, H, Spencer, J.D, Hasse, S, Thornton, M.J, Shalbaf, M, Paus, R, Schallreuter, K.U

“…Senile graying of human hair has been the subject of intense research since ancient times. Reactive oxygen species have been implicated in hair follicle…”
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Enhanced DNA binding capacity on up‐regulated epidermal wild‐type p53 in vitiligo by H2O2‐mediated oxidation: a possible repair mechanism for DNA damage by Salem, Mohamed M. A. E. L., Shalbaf, Mohammad, Gibbons, Nicholas C. J., Chavan, Bhaven, Thornton, J. M., Schallreuter, Karin U.

“…ABSTRACT Vitiligo is characterized by a patchy loss of inherited skin color affecting ̃0.5% of individuals of all races. Despite the absence of the protecting…”
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Neoadjuvant Endocrine Therapy Versus Neoadjuvant Chemotherapy in Node-Positive Invasive Lobular Carcinoma by Thornton, M. J., Williamson, H. V., Westbrook, K. E., Greenup, R. A., Plichta, J. K., Rosenberger, L. H., Gupta, A. M., Hyslop, T., Hwang, E. S., Fayanju, O. M.

“…Background Neoadjuvant chemotherapy (NACT) is often recommended for patients with node-positive invasive lobular carcinoma (ILC) despite unclear benefit in…”
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CATH – a hierarchic classification of protein domain structures by Orengo, CA, Michie, AD, Jones, S, Jones, DT, Swindells, MB, Thornton, JM

“…Background: Protein evolution gives rise to families of structurally related proteins, within which sequence identities can be extremely low. As a result,…”
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Sexual hormones in human skin by Zouboulis, C C, Chen, W-C, Thornton, M J, Qin, K, Rosenfield, R

“…The skin locally synthesizes significant amounts of sexual hormones with intracrine or paracrine actions. The local level of each sexual steroid depends upon…”
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Climate Changes and Their Elevational Patterns in the Mountains of the World by Pepin, N. C., Arnone, E., Gobiet, A., Haslinger, K., Kotlarski, S., Notarnicola, C., Palazzi, E., Seibert, P., Serafin, S., Schöner, W., Terzago, S., Thornton, J. M., Vuille, M., Adler, C.

“…Quantifying rates of climate change in mountain regions is of considerable interest, not least because mountains are viewed as climate “hotspots” where change…”
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Principles of Protein-Protein Interactions by Jones, Susan, Thornton, Janet M.

“…This review examines protein complexes in the Brookhaven Protein Databank to gain a better understanding of the principles governing the interactions involved…”
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Real spherical harmonic expansion coefficients as 3D shape descriptors for protein binding pocket and ligand comparisons by Morris, Richard J., Najmanovich, Rafael J., Kahraman, Abdullah, Thornton, Janet M.

“…Motivation: An increasing number of protein structures are being determined for which no biochemical characterization is available. The analysis of protein…”
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Clinical management of Brucella suis infection in dogs and implications for public health by James, DR, Golovsky, G, Thornton, JM, Goodchild, L, Havlicek, M, Martin, P, Krockenberger, MB, Marriott, DJE, Ahuja, V, Malik, R, Mor, SM

“…Background Brucellosis caused by Brucella suis is a notifiable disease that has recently emerged in dogs in New South Wales (NSW). Given the potential for…”
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Oestrogen functions in skin and skin appendages by Thornton, M J

“…Oestrogens have significant effects on different cell types important in skin physiology, including the epidermal keratinocytes, dermal fibroblasts and…”
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Oestrogen receptor beta is the predominant oestrogen receptor in human scalp skin by Thornton, M. J., Taylor, A. H., Mulligan, K., Al-Azzawi, F., Lyon, C. C., O'Driscoll, J., Messenger, A. G.

“…: Oestrogens play a major role in non‐classic target tissues in both sexes, yet there have been few studies on estrogens and skin. Recently a second oestrogen…”
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A Model Recognition Approach to the Prediction of All-Helical Membrane Protein Structure and Topology by Jones, D. T, Taylor, W. R, Thornton, J. M

“…This paper describes a new method for the prediction of the secondary structure and topology of integral membrane proteins based on the recognition of…”
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Satisfying hydrogen bonding potential in proteins by McDonald, I K, Thornton, J M

“…We have analysed the frequency with which potential hydrogen bond donors and acceptors are satisfied in protein molecules. There are a small percentage of…”
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HydroCoils, Occlusion Rates, and Outcomes: A Large Single-Center Study by O'HARE, A. M, FANNING, N. F, TI, J. P, DUNNE, R, BRENNAN, P. R, THORNTON, J. M

“…The HydroCoil is an expansile hydrogel coil designed to produce a greater degree of volumetric packing within cerebral aneurysms when compared with bare…”
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PROMOTIF—A program to identify and analyze structural motifs in proteins by Hutchinson, E. Gail, Thornton, Janet M.

“…We describe a suite of programs, PROMOTIF, that analyzes a protein coordinate file and provides details about the structural motifs in the protein. The program…”
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A new approach to protein fold recognition by Jones, D. T, Taylort, W. R, Thornton, J. M

“…The prediction of protein tertiary structure from sequence using molecular energy calculations has not yet been successful; an alternative strategy of…”
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Simulating Fully‐Integrated Hydrological Dynamics in Complex Alpine Headwaters: Potential and Challenges by Thornton, J. M., Therrien, R., Mariéthoz, G., Linde, N., Brunner, P.

“…Highly simplified approaches continue to underpin hydrological climate change impact assessments across the Earth's mountainous regions. Fully‐integrated…”
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A revised set of potentials for β‐turn formation in proteins by Hutchinson, E. Gail, Thornton, Janet M.

“…Three thousand eight hundred ninety‐nine β‐turns have been identified and classified using a nonhomologous data set of 205 protein chains. These were used to…”
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