Search Results - "Thornton, J.M"

Modeling studies of the change in conformation required for cleavage of limited proteolytic sites by Hubbard, S.J., Eisenmenger, F, Thornton, J.M.

“…Previous analyses of limited proteolytic sites within native, folded protein structures have shown that a significant conformational change is required in…”
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Efficient multi-objective calibration and uncertainty analysis of distributed snow simulations in rugged alpine terrain by Thornton, J.M., Brauchli, T., Mariethoz, G., Brunner, P.

“…•Snow maps contributed to spatially-explicit energy balance model calibration.•Gravitational snow redistribution was accounted for.•Several important…”
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A mutation data matrix for transmembrane proteins by Jones, D.T., Taylor, W.R., Thornton, J.M.

“…The widely used Mutation Data Matrix (MDM), is an amino acid comparison matrix calculated from a study of the exchange probabilities (or odds) derived from an…”
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804 Overcoming wound healing complications of radiotherapy in breast dermal fibroblasts through the influence of pre-adipocytes by Trevor, L.V., Riches-Suman, K., Mahajan, A., Thornton, J.M.

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Comparison of conformational characteristics in structurally similar protein pairs by Flores, T.P., Orengo, C.A., Moss, D.S., Thornton, J.M.

“…Although it is known that three‐dimensional structure is well conserved during the evolutionary development of proteins, there have been few studies that…”
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Distributions of water around amino acid residues in proteins by Thanki, N, Thornton, J M, Goodfellow, J M

“…The atomic co-ordinates from 16 high-resolution (less than or equal to 1.7 A = 0.1 nm), non-homologous proteins have been used to study the distributions of…”
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Characterization of Atypical Aeromonas salmonicida Different Methods by Austin, B., Austin, D.A., Dalsgaard, I., Gudmundsdóttir, B.K., Høie, S., Thornton, J.M., Larsen, J.L., O'Hici, B., Powell, R.

“…Fifty two isolates of atypical Aeromonas salmonicida, recovered from a wide range of hosts and geographical locations, were heterogeneous in terms of molecular…”
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The interaction between phenylalanine rings in proteins by Singh, J., Thornton, J.M.

“…An analysis has been made of the geometry of phenylalanine-phenylalanine interactions in proteins of known structure. 162 Phe-Phe interactions were found with…”
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Lipoxin A4 promotes reduction and antibiotic efficacy against Pseudomonas aeruginosa biofilm by Thornton, J.M., Walker, J.M., Sundarasivarao, P.Y. Kadiyam, Spur, B.W., Rodriguez, A., Yin, K.

“…•Lipoxin A4 (LxA4) and Resolvin D2 (RvD2) directly reduce Pseudomonas aeruginosa biofilm formation.•LxA4 and RvD2 reduce expression of Pseudomonas aeruginosa…”
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Resolvin D2 promotes host defense in a 2 - hit model of sepsis with secondary lung infection by Walker, J.M., Sundarasivarao, P.Y. Kadiyam, Thornton, J.M., Sochacki, K., Rodriguez, A., Spur, B.W., Acharya, N.K., Yin, K.

“…•A later immunosuppressive phase where the host is unable to clear secondary infections often occurs in sepsis.•RvD2 given at 48 h in a murine model of sepsis,…”
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Location of ‘continuous’ antigenic determinants in the protruding regions of proteins by Thornton, J.M., Edwards, M.S., Taylor, W.R., Barlow, D.J.

“…A simple method is described to locate ‘antigenic’ peptides from the alpha‐carbon co‐ordinates of a protein, based on protrusion from the protein's globular…”
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The geometries of interacting arginine-carboxyls in proteins by Singh, J., Thornton, J.M., Snarey, M., Campbell, S.F.

“…The geometries are reported for interacting arginine-carboxyl pairs obtained from 37 high resolution protein structures solved to a resolution of 2.0 Å or…”
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Modeling birds on wires by Aydoğdu, A., Frasca, P., D'Apice, C., Manzo, R., Thornton, J.M., Gachomo, B., Wilson, T., Cheung, B., Tariq, U., Saidel, W., Piccoli, B.

“…In this paper we introduce a mathematical model to study the group dynamics of birds resting on wires. The model is agent-based and postulates…”
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Structural similarity between the pleckstrin homology domain and verotoxin: The problem of measuring and evaluating structural similarity by Orengo, C.A., Swindells, M.B., Michie, A.D., Zvelebil, M.J., Driscoll, P.C., Waterfield, M.D., Thornton, J.M.

“…An unexpected structural similarity is described between the pleckstrin homology (PH) domain and verotoxin. This similarity has escaped detection primarily due…”
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The BC loop in poliovirus coat protein VP1: an ideal acceptor site for major insertions by Stirk, H J, Thornton, J M

“…In poliovirus the BC loop of the VP1 coat protein is hypervariable and can accommodate numerous foreign sequences introduced by genetic engineering. This paper…”
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From structure to function: approaches and limitations by Thornton, J M, Todd, A E, Milburn, D, Borkakoti, N, Orengo, C A

“…This review presents a summary of current approaches to extract functional information from structural data on proteins and their complexes. While structural…”
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HydroCoils, Occlusion Rates, and Outcomes: A Large Single-Center Study by O'HARE, A. M, FANNING, N. F, TI, J. P, DUNNE, R, BRENNAN, P. R, THORNTON, J. M

“…The HydroCoil is an expansile hydrogel coil designed to produce a greater degree of volumetric packing within cerebral aneurysms when compared with bare…”
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Protein superfamilies and domain superfolds by Orengo, C.A, Jones, D.T, Thornton, J.M

“…As the protein sequence and structure databases expand rapidly a better understanding of the relationships between proteins is required. A classification is…”
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CATH database provides insights into protein structure/function relationships by Orengo, C.A, Pearl, F.M.G, Bray, J.E, Todd, A.E, Martin, A.C, Lo Conte, L, Thornton, J.M

“…We report the latest release (version 1.4) of the CATH protein domains database (http://www.biochem.ucl.ac.uk/bsm/cath). This is a hierarchical classification…”
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Analysis and prediction of the different types of beta-turn in proteins by Wilmot, C M, Thornton, J M

“…beta-Turns have been extracted from 59 non-identical proteins (resolution 2 A) using the standard criterion that the distance between C alpha (i) and C alpha…”
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