Search Results - "Thorner, Konrad"
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Use of phage display biopanning as a tool to design CAR-T cells against glioma stem cells
Published in Frontiers in oncology (24-03-2023)“…Glioblastoma (GBM) is both the most common and aggressive type of primary brain tumor, associated with high mortality rates and resistance to conventional…”
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STEM-14. GLIOBLASTOMA STEM CELL TARGETING CHIMERIC ANTIGEN RECEPTOR T CELLS MODIFIED USING PHAGE DISPLAY ISOLATED PEPTIDES
Published in Neuro-oncology (Charlottesville, Va.) (09-11-2020)“…Glioblastoma (GBM) is the most aggressive primary brain tumor with high mortality rates and resistance to conventional therapy. Their resistance to…”
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Transplanted human intestinal organoids: a resource for modeling human intestinal development
Published in Development (Cambridge) (01-05-2023)“…The in vitro differentiation of pluripotent stem cells into human intestinal organoids (HIOs) has served as a powerful means for creating complex…”
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CAR-T Engineering: Optimizing Signal Transduction and Effector Mechanisms
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01-12-2019)“…The adoptive transfer of genetically engineered T cells expressing a chimeric antigen receptor (CAR) has shown remarkable results against B cell malignancies…”
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Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation
Published in Development (Cambridge) (15-04-2023)“…Primary cilia are nearly ubiquitous organelles that transduce molecular and mechanical signals. Although the basic structure of the cilium and the cadre of…”
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