Search Results - "Thorne, P.R"

Reduced sensory stimulation alters the molecular make-up of glutamatergic hair cell synapses in the developing cochlea by Barclay, M, Constable, R, James, N.R, Thorne, P.R, Montgomery, J.M

“…Highlights • Normal acoustic stimulation in the 2 weeks after the onset of hearing is not required for maintenance of afferent innervation of the inner hair…”
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Noise exposure induces up-regulation of ecto-nucleoside triphosphate diphosphohydrolases 1 and 2 in rat cochlea by Vlajkovic, S.M, Housley, G.D, Muñoz, D.J.B, Robson, S.C, Sévigny, J, Wang, C.J.H, Thorne, P.R

“…Extracellular ATP acting via P2 receptors in the inner ear initiates a variety of signaling pathways that may be involved in noise-induced cochlear injury…”
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Quinacrine staining of marginal cells in the stria vascularis of the guinea-pig cochlea: a possible source of extracellular ATP? by White, P.N., Thorne, P.R., Housley, G.D., Mockett, B., Billett, T.E., Burnstock, G.

“…There is accumulating evidence for a purinergic humoral system involved in the control of cochlear function. Evidence of specific P 2 purinoceptors on cochlear…”
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High frequency bone conduction auditory evoked potentials in the guinea pig: Assessing cochlear injury after ossicular chain manipulation by Bergin, M.J., Bird, P.A., Vlajkovic, S.M., Thorne, P.R.

“…Permanent high frequency (>4 kHz) sensorineural hearing loss following middle ear surgery occurs in up to 25% of patients. The aetiology of this loss is poorly…”
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Species differences in the distribution of infracuticular F-actin in outer hair cells of the cochlea by Carlisle, L, Zajic, G, Altschuler, R A, Schacht, J, Thorne, P R

“…The distribution of filamentous actin (F-actin) in outer hair cells has been examined in several mammalian species using tetramethylrhodamine phalloidin, a…”
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The pathogenesis of stereocilia abnormalities in acoustic trauma by Thorne, P R, Duncan, C E, Gavin, J B

“…Stereocilia abnormalities develop in anesthetized guinea pigs within two minutes of exposure to loud sound (3 kHz, 125 dB SPL). Displacement, fracture, fusion…”
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Ensemble spontaneous activity in the guinea-pig cochlear nerve by Searchfield, G.D., Muñoz, D.J.B., Thorne, P.R.

“…Spectral analysis of electrical noise recorded from the round window (RW) of the cochlea is referred to as the ensemble spontaneous activity (ESA) of the…”
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Purinergic regulation of sound transduction and auditory neurotransmission by Housley, G D, Jagger, D J, Greenwood, D, Raybould, N P, Salih, S G, Järlebark, L E, Vlajkovic, S M, Kanjhan, R, Nikolic, P, Muñoz, D J M, Thorne, P R

“…In the cochlea, extracellular ATP influences the endocochlear potential, micromechanics, and neurotransmission via P2 receptors. Evidence for this arises from…”
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Fluorescence imaging of Na + influx via P2X receptors in cochlear hair cells by Housley, G.D, Raybould, N.P, Thorne, P.R

“…The adenosine 5′-triphosphate (ATP)-activated membrane conductance, mediated by P2X receptors, was examined in isolated guinea-pig cochlear inner and outer…”
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Laser Doppler measurements of cochlear blood flow during loud sound exposure in the guinea pig by Thorne, P R, Nuttall, A L

“…This investigation examined the effects of loud sound of different frequencies and intensities on cochlear blood flow as measured by the laser Doppler…”
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Sound-induced artifact in cochlear blood flow measurements using the laser Doppler flowmeter by Thorne, P R, Nuttall, A L, Scheibe, F, Miller, J M

“…The laser Doppler flowmeter has been shown to give a response from the cochlea during high intensity acoustic stimulation which is not related to blood flow…”
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