Search Results - "Thorne, Grace"

Daptomycin: a lipopeptide antibiotic for the treatment of serious Gram-positive infections by Steenbergen, Judith N., Alder, Jeff, Thorne, Grace M., Tally, Francis P.

“…Infections caused by drug-resistant pathogens are on the rise. Daptomycin, a cyclic lipopeptide with activity against most Gram-positive pathogens, including…”
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Effects of Prior Effective Therapy on the Efficacy of Daptomycin and Ceftriaxone for the Treatment of Community-Acquired Pneumonia by Pertel, Peter E., Bernardo, Patricia, Fogarty, Charles, Matthews, Peter, Northland, Rebeca, Benvenuto, Mark, Thorne, Grace M., Luperchio, Steven A., Arbeit, Robert D., Alder, Jeff

“…Objective. We sought to compare daptomycin with ceftriaxone for the treatment of patients with community-acquired pneumonia (CAP). Methods. Two phase-3…”
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Effects of daptomycin in combination with other antimicrobial agents: a review of in vitro and animal model studies by Steenbergen, Judith N., Mohr, John F., Thorne, Grace M.

“…This review summarizes the in vitro and animal model data available on antibiotic combinations with daptomycin. The majority of studies focus on the clinically…”
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Structure–Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea by Yin, Ning, Li, Jing, He, Yong, Herradura, Prudencio, Pearson, Andre, Mesleh, Michael F, Mascio, Carmela T, Howland, Karen, Steenbergen, Judith, Thorne, Grace M, Citron, Diane, Van Praagh, Andrew D. G, Mortin, Lawrence I, Keith, Dennis, Silverman, Jared, Metcalf, Chester

“…Novel cyclic lipopeptides with different acyl tails were synthesized via a semisynthetic approach. Structure–activity relationship studies revealed that…”
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Use of linezolid susceptibility test results as a surrogate for the susceptibility of Gram-positive pathogens to tedizolid, a novel oxazolidinone by Zurenko, Gary, Bien, Paul, Bensaci, Mekki, Patel, Hina N, Thorne, Grace

“…Tedizolid is a novel oxazolidinone antibacterial with potent activity against a wide range of Gram-positive pathogens, including methicillin-resistant…”
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In vitro activity of daptomycin against clinical isolates with reduced susceptibilities to linezolid and quinupristin/dalfopristin by Anastasiou, Diane M., Thorne, Grace M., Luperchio, Steven A., Alder, Jeff D.

“…An initiative was taken to determine the in vitro activity of daptomycin against 85 Gram-positive isolates with reduced susceptibilities to linezolid and…”
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Impaired Innate Immunity in the Newborn: Newborn Neutrophils Are Deficient in Bactericidal/Permeability-Increasing Protein by Levy, Ofer, Martin, Sara, Eichenwald, Eric, Ganz, Tomas, Valore, Erika, Carroll, Stephen F, Lee, Kelly, Goldmann, Donald, Thorne, Grace M

“…The mechanisms by which newborns are at increased risk for invasive bacterial infections have been incompletely defined. A central element of innate immunity…”
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Multicenter Evaluation of the Etest and Disk Diffusion Methods for Differentiating Daptomycin-Susceptible from Non-Daptomycin-Susceptible Staphylococcus aureus Isolates by Jevitt, Laura A, Thorne, Grace M, Traczewski, Maria M, Jones, Ronald N, McGowan, John E. Jr, Tenover, Fred C, Brown, Steven D

“…Daptomycin is a novel cyclic lipopeptide that is approved by the U.S. Food and Drug Administration for the treatment of complicated skin and skin structure…”
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Daptomycin tested against 915 bloodstream isolates of viridans group streptococci (eight species) and Streptococcus bovis by Streit, Jennifer M., Steenbergen, Judith N., Thorne, Grace M., Alder, Jeffrey, Jones, Ronald N.

“…Objectives: To evaluate the activity of daptomycin tested against numerous species of viridans group streptococci and Streptococcus bovis, which are associated…”
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Daptomycin In Vitro Susceptibility Methodology: a Review of Methods, Including Determination of Calcium in Testing Media by Koeth, Laura M., MT(ASCP), Thorne, Grace M., Ph.D

“…Abstract Daptomycin has been available as a gram-positive antimicrobial agent in the United States for over 6 years, and during this time there have been…”
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Detection of daptomycin-nonsusceptible strains using the Neo-Sensitab™ prediffusion method by Katz, Bradley D, Luperchio, Steven A, Thorne, Grace M

“…Abstract Two prediffusion methods with daptomycin (DAP) Neo-Sensitabs were evaluated against a challenge set of 30 Staphylococcus aureus isolates and 30…”
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Analysis of Daptomycin Efficacy and Breakpoint Standards in a Murine Model of Enterococcus faecalis and Enterococcus faecium Renal Infection by Alder, Jeff, Li, Tongchaun, Yu, Donghui, Morton, Larry, Silverman, Jared, Zhang, Xi-Xian, Critchley, Ian, Thorne, Grace

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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In vitro activity of daptomycin against multidrug-resistant Staphylococcus aureus and S. aureus with known virulence factors, including community-acquired methicillin-resistant isolates by Anastasiou, Diane M, Morgan, Margie, Ruane, Peter J, Steenbergen, Judith N, Katz, Bradley D, Alder, Jeff D, Thorne, Grace M

“…Abstract The in vitro activity of daptomycin was evaluated against 360 multidrug-resistant Staphylococcus aureus isolates (including hospital-acquired…”
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Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke by Priest, Naomi, Roseby, Rob, Waters, Elizabeth, Polnay, Adam, Campbell, Rona, Spencer, Nick, Webster, Premila, Ferguson-Thorne, Grace

“…Children's exposure to other people's cigarette smoke (environmental tobacco smoke, or ETS) is associated with a range of adverse health outcomes for children…”
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Surotomycin Demonstrates Low In Vitro Frequency of Resistance and Rapid Bactericidal Activity in Clostridium difficile, Enterococcus faecalis, and Enterococcus faecium by MASCIO, Carmela T. M, CHESNEL, Laurent, THORNE, Grace, SILVERMAN, Jared A

“…Surotomycin (CB-183,315) is an orally administered, minimally absorbed, selective bactericidal cyclic lipopeptide in phase 3 development for the treatment of…”
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Chronic Parvovirus B19 Infection Resulting in Chronic Fatigue Syndrome: Case History and Review by Jacobson, S. Kim, Daly, Jennifer S., Thorne, Grace M., McIntosh, Kenneth

“…The spectrum of disease caused by parvovirus B19 has been expanding in recent years because of improved and more sensitive methods of detection. There is…”
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Immune response to Escherichia coli O157:H7 in hemolytic uremic syndrome following salmonellosis by FLORES, F. X, JABS, K, THORNE, G. M, JAEGER, J, LINSHAW, M. A, SOMERS, M. J. G

“…Escherichia coli O157:H7, a Shiga-like toxin (SLT)-producing enteric pathogen, has been implicated in most cases of post-diarrheal hemolytic uremic syndrome (D…”
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Neonatal herpes simplex virus infection presenting as fulminant liver failure by Greenes, D S, Rowitch, D, Thorne, G M, Perez-Atayde, A, Lee, F S, Goldmann, D

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Evidence for daptomycin Etest lot-related MIC elevations for Staphylococcus aureus by Friedrich, Lawrence, Thorne, Grace, Steenbergen, Judith N, Anastasiou, Diane, Koeth, Laura

“…Abstract MIC testing was performed simultaneously by Etest and broth microdilution (BMD) on 587 Staphylococcus aureus isolates submitted by local laboratories…”
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Daptomycin: a novel lipopeptide antibiotic by Thorne, Grace M., Alder, Jeff

“…Daptomycin is a novel lipopeptide antibiotic with rapid in vitro bactericidal against activity virtually all gram-positive pathogens. The spectrum of activity…”
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