Search Results - "Thorn, S"

Improved blue, green, and red fluorescent protein tagging vectors for S. cerevisiae by Lee, Sidae, Lim, Wendell A, Thorn, Kurt S

“…Fluorescent protein fusions are a powerful tool to monitor the localization and trafficking of proteins. Such studies are particularly easy to carry out in the…”
Get full text

A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1 by Hertz, Nicholas T., Berthet, Amandine, Sos, Martin L., Thorn, Kurt S., Burlingame, Al L., Nakamura, Ken, Shokat, Kevan M.

“…Mitochondria have long been implicated in the pathogenesis of Parkinson’s disease (PD). Mutations in the mitochondrial kinase PINK1 that reduce kinase activity…”
Get full text

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response by Schuck, Sebastian, Prinz, William A, Thorn, Kurt S, Voss, Christiane, Walter, Peter

“…Cells constantly adjust the sizes and shapes of their organelles according to need. In this study, we examine endoplasmic reticulum (ER) membrane expansion…”
Get full text

The cancer glycocalyx mechanically primes integrin-mediated growth and survival by Paszek, Matthew J., DuFort, Christopher C., Rossier, Olivier, Bainer, Russell, Mouw, Janna K., Godula, Kamil, Hudak, Jason E., Lakins, Jonathon N., Wijekoon, Amanda C., Cassereau, Luke, Rubashkin, Matthew G., Magbanua, Mark J., Thorn, Kurt S., Davidson, Michael W., Rugo, Hope S., Park, John W., Hammer, Daniel A., Giannone, Grégory, Bertozzi, Carolyn R., Weaver, Valerie M.

“…Malignancy is associated with altered expression of glycans and glycoproteins that contribute to the cellular glycocalyx. We constructed a glycoprotein…”
Get full text

Optimized cassettes for fluorescent protein tagging in Saccharomyces cerevisiae by Sheff, Mark A., Thorn, Kurt S.

“…Green fluorescent protein (GFP) has become an increasingly popular protein tag for determining protein localization and abundance. With the availability of GFP…”
Get full text

An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics by Slade, Elisabeth A, Thorn, Robin M S, Young, Amber, Reynolds, Darren M

“…The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo…”
Get full text

High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation by Staudt, David W, Liu, Jiandong, Thorn, Kurt S, Stuurman, Nico, Liebling, Michael, Stainier, Didier Y R

“…Over the course of development, the vertebrate heart undergoes a series of complex morphogenetic processes that transforms it from a simple myocardial…”
Get full text

Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells by Robson, J. L., Thorn, R. M. S., Williams, A. C., Collard, T. J., Qualtrough, D.

“…Colorectal cancer (CRC) is a significant global health burden with a rising incidence worldwide. Distinct bacterial populations are associated with CRC…”
Get full text

Protocolised thromboelastometric‐guided haemostatic management in patients with traumatic brain injury: a pilot study by Gratz, J., Güting, H., Thorn, S., Brazinova, A., Görlinger, K., Schäfer, N., Schöchl, H., Stanworth, S., Maegele, M.

“…Summary Coagulopathy in patients with traumatic brain injury is associated with an increase in morbidity and mortality. Although timely and aggressive…”
Get full text

CineCT platform for in vivo and ex vivo measurement of 3D high resolution Lagrangian strains in the left ventricle following myocardial infarction and intramyocardial delivery of theranostic hydrogel by Midgett, D.E., Thorn, S.L., Ahn, S.S., Uman, S., Avendano, R., Melvinsdottir, I., Lysyy, T., Kim, J.S., Duncan, J.S., Humphrey, J.D., Papademetris, X., Burdick, J.A., Sinusas, A.J.

“…Myocardial infarction (MI) produces acute changes in strain and stiffness within the infarct that can affect remote areas of the left ventricle (LV) and drive…”
Get full text

Mitochondrial Network Size Scaling in Budding Yeast by Rafelski, Susanne M., Viana, Matheus P., Zhang, Yi, Chan, Yee-Hung M., Thorn, Kurt S., Yam, Phoebe, Fung, Jennifer C., Li, Hao, da F. Costa, Luciano, Marshall, Wallace F.

“…Mitochondria must grow with the growing cell to ensure proper cellular physiology and inheritance upon division. We measured the physical size of mitochondrial…”
Get full text

Electrochemically activated solutions: evidence for antimicrobial efficacy and applications in healthcare environments by Thorn, R. M. S., Lee, S. W. H., Robinson, G. M., Greenman, J., Reynolds, D. M.

“…Due to the limitations associated with the use of existing biocidal agents, there is a need to explore new methods of disinfection to help maintain effective…”
Get full text

High-resolution solid-state manometry of the effect of rocuronium on barrierpressure by AHLSTRAND, R., THÖRN, S.-E., WATTWIL, M.

“…Background The pressure in the lower esophageal sphincter (LES) is partly dependent on striated muscles derived from the crural portion of the diaphragm. The…”
Get full text

Ultrasonography-guided radial artery catheterization is superior compared with the traditional palpation technique by HANSEN, M. A., JUHL-OLSEN, P., THORN, S., FREDERIKSEN, C. A., SLOTH, E.

“…Background Radial artery catheterization is gaining popularity for diagnostic and interventional procedures. Palpation technique is widely used for the…”
Get full text

Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads by Nguyen, Huy Quoc, Roy, Jagoree, Harink, Björn, Damle, Nikhil P, Latorraca, Naomi R, Baxter, Brian C, Brower, Kara, Longwell, Scott A, Kortemme, Tanja, Thorn, Kurt S, Cyert, Martha S, Fordyce, Polly Morrell

“…Transient, regulated binding of globular protein domains to Short Linear Motifs (SLiMs) in disordered regions of other proteins drives cellular signaling…”
Get full text

Anatomy of hot spots in protein interfaces by Bogan, Andrew A, Thorn, Kurt S

“…Binding of one protein to another is involved in nearly all biological functions, yet the principles governing the interaction of proteins are not fully…”
Get full text

Ecological niche modelling as a technique for assessing threats and setting conservation priorities for Asian slow lorises (Primates: Nycticebus) by Thorn, J. S., Nijman, V., Smith, D., Nekaris, K. A. I.

“…Data on geographical ranges are essential when defining the conservation status of a species, and in evaluating levels of human disturbance. Where locality…”
Get full text

Beauty and the beast: how a bat utilizes forests shaped by outbreaks of an insect pest by Kortmann, M., Hurst, J., Brinkmann, R., Heurich, M., Silveyra González, R., Müller, J., Thorn, S.

“…The consequences of different management strategies following natural disturbances are a matter of global concern. In former production forests around the…”
Get full text

Ultrasonography-guided radial artery catheterization is superior compared with the traditional palpation technique: a prospective, randomized, blinded, crossover study by Hansen, M A, Juhl-Olsen, P, Thorn, S, Frederiksen, C A, Sloth, E

“…Radial artery catheterization is gaining popularity for diagnostic and interventional procedures. Palpation technique is widely used for the procedure, but…”
Get full text

Real-Time Imaging of Discrete Exocytic Events Mediating Surface Delivery of AMPA Receptors by Yudowski, Guillermo A, Puthenveedu, Manojkumar A, Leonoudakis, Dmitri, Panicker, Sandip, Thorn, Kurt S, Beattie, Eric C, von Zastrow, Mark

“…We directly resolved discrete exocytic fusion events mediating insertion of AMPA-type glutamate receptors (AMPARs) to the somatodendritic surface of rat…”
Get full text