Search Results - "Thorn, Lena"

Lessons learned from the FinnDiane Study: Epidemiology and metabolic risk factors for diabetic kidney disease in type 1 diabetes by Jansson Sigfrids, Fanny, Lithovius, Raija, Groop, Per-Henrik, Thorn, Lena M

“…Across its operational span of more than 25 years, the observational, nationwide, multicentre Finnish Diabetic Nephropathy (FinnDiane) Study has aimed to…”
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Physical Activity Reduces Risk of Premature Mortality in Patients With Type 1 Diabetes With and Without Kidney Disease by Tikkanen-Dolenc, Heidi, Wadén, Johan, Forsblom, Carol, Harjutsalo, Valma, Thorn, Lena M, Saraheimo, Markku, Elonen, Nina, Tikkanen, Heikki O, Groop, Per-Henrik

“…The aims of the study were to assess how baseline leisure-time physical activity (LTPA) and its exercise components intensity, duration, and frequency are…”
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Prognosis After First-Ever Myocardial Infarction in Type 1 Diabetes Is Strongly Affected by Chronic Kidney Disease by Smidtslund, Patrik, Jansson Sigfrids, Fanny, Ylinen, Anni, Elonen, Nina, Harjutsalo, Valma, Groop, Per-Henrik, Thorn, Lena M

“…To study prognosis after a first-ever myocardial infarction (MI) in type 1 diabetes, as well as how different MI- and diabetes-related factors affect the…”
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A1C Variability Predicts Incident Cardiovascular Events, Microalbuminuria, and Overt Diabetic Nephropathy in Patients With Type 1 Diabetes by WADEN, Johan, FORSBLOM, Carol, THORN, Lena M, GORDIN, Daniel, SARAHEIMO, Markku, GROOP, Per-Henrik

“…A1C Variability Predicts Incident Cardiovascular Events, Microalbuminuria, and Overt Diabetic Nephropathy in Patients With Type 1 Diabetes Johan Wadén 1 , 2 ,…”
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The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes by THOMAS, Merlin C, MORAN, John L, WADEN, Johan, THORN, Lena M, MÄKINEN, Ville-Petteri, ROSENGARD-BÄRLUND, Milla, SARAHEIMO, Markku, HIETALA, Kustaa, HEIKKILÄ, Outi, FORSBLOM, Carol

“…The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes Per-Henrik Groop 1 , 2 , Merlin C. Thomas 3 , John L. Moran…”
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Relationship Between Abdominal Fatness and Onset and Progression of Albuminuria in Type 1 Diabetes by Parente, Erika B, Mutter, Stefan, Thorn, Lena M, Harjutsalo, Valma, Groop, Per-Henrik

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Urinary metabolite profiling and risk of progression of diabetic nephropathy in 2670 individuals with type 1 diabetes by Mutter, Stefan, Valo, Erkka, Aittomäki, Viljami, Nybo, Kristian, Raivonen, Lassi, Thorn, Lena M., Forsblom, Carol, Sandholm, Niina, Würtz, Peter, Groop, Per-Henrik

“…Aims/hypothesis This prospective, observational study examines associations between 51 urinary metabolites and risk of progression of diabetic nephropathy in…”
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Retinal artery to vein ratio is associated with cerebral microbleeds in individuals with type 1 diabetes by Tarkkonen, Aleksi, Fickweiler, Ward, Eriksson, Marika, Sun, Jennifer K, Thorn, Lena M, Summanen, Paula, Groop, Per-Henrik, Putaala, Jukka, Martola, Juha, Gordin, Daniel

“…A third of asymptomatic individuals with type 1 diabetes (T1D) show signs of cerebrovascular disease in brain MRI. These signs associate with advanced stages…”
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The Presence and Consequence of Nonalbuminuric Chronic Kidney Disease in Patients With Type 1 Diabetes by Thorn, Lena M, Gordin, Daniel, Harjutsalo, Valma, Hägg, Stefanie, Masar, Robert, Saraheimo, Markku, Tolonen, Nina, Wadén, Johan, Groop, Per-Henrik, Forsblom, Carol M

“…This study investigated the prevalence of nonalbuminuric chronic kidney disease in type 1 diabetes to assess whether it increases the risk of cardiovascular…”
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Excessive occupational sitting increases risk of cardiovascular events among working individuals with type 1 diabetes in the prospective Finnish Diabetic Nephropathy Study by Seppälä, Matias, Lukander, Heidi, Wadén, Johan, Eriksson, Marika I, Harjutsalo, Valma, Groop, Per-Henrik, Thorn, Lena M

“…Sedentary behavior, such as excessive sitting, increases risk of cardiovascular disease and premature mortality in the general population, but this has not…”
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Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes by Antikainen, Anni A., Haukka, Jani K., Kumar, Anmol, Syreeni, Anna, Hägg-Holmberg, Stefanie, Ylinen, Anni, Kilpeläinen, Elina, Kytölä, Anastasia, Palotie, Aarno, Putaala, Jukka, Thorn, Lena M., Harjutsalo, Valma, Groop, Per-Henrik, Sandholm, Niina

“…Individuals with type 1 diabetes (T1D) carry a markedly increased risk of stroke, with distinct clinical and neuroimaging characteristics as compared to those…”
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Regression of albuminuria and its association with incident cardiovascular outcomes and mortality in type 1 diabetes: the FinnDiane Study by Jansson, Fanny J., Forsblom, Carol, Harjutsalo, Valma, Thorn, Lena M., Wadén, Johan, Elonen, Nina, Ahola, Aila J., Saraheimo, Markku, Groop, Per-Henrik

“…Aims/hypothesis Our aim was to assess regression of albuminuria and its clinical consequences in type 1 diabetes. Methods The analysis included 3642…”
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Body Mass Index and Mortality in Individuals With Type 1 Diabetes by Dahlström, Emma H, Sandholm, Niina, Forsblom, Carol M, Thorn, Lena M, Jansson, Fanny J, Harjutsalo, Valma, Groop, Per-Henrik

“…Abstract Context The relationship between body mass index (BMI) and mortality may differ between patients with type 1 diabetes and the general population; it…”
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Insulin sensitivity estimates and their longitudinal association with coronary artery disease in type 1 diabetes. Does it matter? by Mutter, Stefan, Parente, Erika B, Januszewski, Andrzej S, Simonsen, Johan R, Harjutsalo, Valma, Groop, Per-Henrik, Jenkins, Alicia J, Thorn, Lena M

“…Insulin resistance and chronic kidney disease are both associated with increased coronary artery disease risk. Many formulae estimating glucose disposal rate…”
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Frequent and intensive physical activity reduces risk of cardiovascular events in type 1 diabetes by Tikkanen-Dolenc, Heidi, Wadén, Johan, Forsblom, Carol, Harjutsalo, Valma, Thorn, Lena M., Saraheimo, Markku, Elonen, Nina, Rosengård-Bärlund, Milla, Gordin, Daniel, Tikkanen, Heikki O., Groop, Per-Henrik

“…Aims/hypothesis Cardiovascular disease (CVD) is the most common cause of premature death and disability among patients with type 1 diabetes. Diabetic…”
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Stroke incidence increases with diabetic retinopathy severity and macular edema in type 1 diabetes by Eriksson, Marika I, Hietala, Kustaa, Summanen, Paula, Harjutsalo, Valma, Putaala, Jukka, Ylinen, Anni, Hägg-Holmberg, Stefanie, Groop, Per-Henrik, Thorn, Lena M

“…As the retina is suggested to mirror the brain, we hypothesized that diabetic retinopathy and macular edema are indicative of stroke risk in type 1 diabetes…”
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Kidney injury molecule-1 and the loss of kidney function in diabetic nephropathy: a likely causal link in patients with type 1 diabetes by Panduru, Nicolae M, Sandholm, Niina, Forsblom, Carol, Saraheimo, Markku, Dahlström, Emma H, Thorn, Lena M, Gordin, Daniel, Tolonen, Nina, Wadén, Johan, Harjutsalo, Valma, Bierhaus, Angelika, Humpert, Per M, Groop, Per-Henrik

“…We evaluated the predictive value and clinical benefit of urinary kidney injury molecule (KIM)-1 for progression of diabetic nephropathy (DN) in type 1…”
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Haptoglobin Genotype Does Not Confer a Risk of Stroke in Type 1 Diabetes by Syreeni, Anna, Dahlström, Emma H, Hägg-Holmberg, Stefanie, Forsblom, Carol, Eriksson, Marika I, Harjutsalo, Valma, Putaala, Jukka, Groop, Per-Henrik, Sandholm, Niina, Thorn, Lena M

“…The exon copy number variant in the haptoglobin gene is associated with cardiovascular and kidney disease. For stroke, previous research is inconclusive. We…”
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The Low-Expression Variant of FABP4 Is Associated With Cardiovascular Disease in Type 1 Diabetes by Dahlström, Emma H, Saksi, Jani, Forsblom, Carol, Uglebjerg, Nicoline, Mars, Nina, Thorn, Lena M, Harjutsalo, Valma, Rossing, Peter, Ahluwalia, Tarunveer S, Lindsberg, Perttu J, Sandholm, Niina, Groop, Per-Henrik

“…Fatty acid binding protein 4 (FABP4) is implicated in the pathogenesis of cardiometabolic disorders. Pharmacological inhibition or genetic deletion of FABP4…”
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Incidence of Stroke According to Presence of Diabetic Nephropathy and Severe Diabetic Retinopathy in Patients With Type 1 Diabetes by HÄGG, Stefanie, THORN, Lena M, PUTAALA, Jukka, LIEBKIND, Ron, HARJUTSALO, Valma, FORSBLOM, Carol M, GORDIN, Daniel, TATLISUMAK, Turgut, GROOP, Per-Henrik

“…Type 1 diabetes is associated with a markedly increased risk of stroke, but only a few studies on the incidence of stroke in type 1 diabetes exist. Therefore,…”
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