Search Results - "Thormann, Ursula"
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Anti-trypanosomal cadinanes synthesized by transannular cyclization of the natural sesquiterpene lactone nobilin
Published in Bioorganic & medicinal chemistry (01-04-2015)“…[Display omitted] Acid-catalyzed transannular cyclization of the germacrene-type sesquiterpene lactone nobilin 1 was investigated with the aim of obtaining new…”
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Formulation and dermal delivery of a new active pharmaceutical ingredient in an in vitro wound model for the treatment of chronic ulcers
Published in European journal of pharmaceutics and biopharmaceutics (01-09-2024)“…[Display omitted] The aim of this study was to investigate dermal delivery of the new active pharmaceutical ingredient (API) TOP-N53 into diabetic foot ulcer…”
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Investigation of drug dissolution and uptake from low-density DPI formulations in an impactor–integrated cell culture model
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2020)“…[Display omitted] Besides deposition, pulmonary bioavailability is determined by dissolution of particles in the scarce epithelial fluid and by cellular API…”
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Mechanism of chemical degradation and determination of solubility by kinetic modeling of the highly unstable sesquiterpene lactone nobilin in different media
Published in Journal of pharmaceutical sciences (01-10-2014)“…The objective of this work was first to investigate the chemical degradation of the sesquiterpene lactone nobilin and determine its solubility under conditions…”
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Evaluation of Intestinal Permeability of Vicenin‑2 and Lychnopholic Acid from Lychnophora salicifolia (Brazilian Arnicão) Using Caco‑2 Cells
Published in Journal of natural products (Washington, D.C.) (28-03-2014)“…Lychnophora salicifolia, commonly known as “arnicão”, is used as an anti-inflammatory agent and as a flavoring agent in the Brazilian traditional spirit…”
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