Search Results - "Thoreau, E."

Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor‐γ agonist trifarotene by Aubert, J., Piwnica, D., Bertino, B., Blanchet‐Réthoré, S., Carlavan, I., Déret, S., Dreno, B., Gamboa, B., Jomard, A., Luzy, A.P., Mauvais, P., Mounier, C., Pascau, J., Pelisson, I., Portal, T., Rivier, M., Rossio, P., Thoreau, E., Vial, E., Voegel, J.J.

“…Summary Background First‐ and third‐generation retinoids are the main treatment for acne. Even though efficacious, they lack full selectivity for retinoic acid…”
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Pharmacology of trifarotene by Aubert, J., Piwnica, D., Bertino, B., Blanchet‐Réthoré, S., Carlavan, I., Déret, S., Dreno, B., Gamboa, B., Jomard, A., Luzy, A.P., Mauvais, P., Mounier, C., Pascau, J., Pelisson, I., Portal, T., Rivier, M., Rossio, P., Thoreau, E., Vial, E., Voegel, J.J.

“…Summary Acne is a chronic inflammatory skin disease, linked to changes in hormone levels. It mainly affects adolescents and young adults, and may lead to…”
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Trifarotene的药理学 by Aubert, J., Piwnica, D., Bertino, B., Blanchet‐Réthoré, S., Carlavan, I., Déret, S., Dreno, B., Gamboa, B., Jomard, A., Luzy, A.P., Mauvais, P., Mounier, C., Pascau, J., Pelisson, I., Portal, T., Rivier, M., Rossio, P., Thoreau, E., Vial, E., Voegel, J.J.

“…Summary 痤疮是一种慢性炎症性皮肤病,与激素水平变动有关。它主要影响青少年和年轻人,可能导致永久性疤痕。15亿15岁至45岁之间的人群曾患上某种形式的痤疮 ‐…”
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Structural symmetry of the extracellular domain of the Cytokine/Growth hormone/Prolactin receptor family and Interferon receptors revealed by Hydrophobic Cluster Analysis by Thoreau, E., Petridou, B., Kelly, P.A., Djiane, J., Mornon, J.P.

“…Sequence comparison based on Hydrophobic Cluster Analysis procedures shows that the extracellular ≈ 200 amino acids domains of cytokines receptors belonging to…”
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Homology modeling of rabbit prolactin hormone complexed with its receptor by Halaby, D., Thoreau, E., Djiane, J., Mornon, J.-P.

“…The pituitary hormone prolactin (prl) is implicated in a number of biological functions, especially lactation, which is mediated through specific lactogenic…”
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LB1570 Structure-based design of Trifarotene, a potent and selective RAR agonist for the treatment of acne by Thoreau, E., Arlabosse, J., Bouix-peter, C., Chambon, S., Chantalat, L., Daver, S., Dumais, L., Duvert, G., Feret, A., Ouvry, G., Pascau, J., Raffin, C., Rodeville, N., Soulet, C., Tabet, S., Talano, S., Portal, T.

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LB1569 Non-clinical and human pharmacology of the potent and selective topical RARγ agonist trifarotene by Aubert, J., Bertino, B., Blanchét-Rethore, S., Carlavan, I., Deret, S., Dréno, B., Luzy, A., Mounier, C., Pascau, J., Pelisson, I., Portal, T., Rivier, M., Rosso, P., Thoreau, E., Vial, E., Voegel, J.J.

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Critical role of the H6-H7 loop in the conformational adaptation of all-trans retinoic acid and synthetic retinoids within the ligand-binding site of RARalpha by Mailfait, S, Thoreau, E, Belaiche, D, Formstecher And B Sablonnie, P

“…The pleiotropic effects of the natural and synthetic retinoids are mediated by the activation of the two subfamilies of nuclear receptors, the retinoic acid…”
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A genetic algorithm for the automated generation of small organic molecules: drug design using an evolutionary algorithm by Douguet, D, Thoreau, E, Grassy, G

“…Rational drug design involves finding solutions to large combinatorial problems for which an exhaustive search is impractical. Genetic algorithms provide a…”
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Critical sites: a semantic approach to protein sequences. Application to the HIV-1 envelope molecule by Zagury, J F, Cantalloube, H, Bernard, J, Lachgar, A, Fall, L, Achour, A, Mbika, J P, Cosme, M H, Pellion, F, Issing, W

“…We have designed two software systems allowing the study of proteins through a comparison to those stored in data banks. The first one, "Automat", locates in a…”
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Rhenium Carbonyl Complexes of .beta.-Estradiol Derivatives with High Affinity for the Estradiol Receptor: An Approach to Selective Organometallic Radiopharmaceuticals by Top, Siden, El Hafa, Hassane, Vessieres, Anne, Quivy, Jacques, Vaissermann, Jacqueline, Hughes, Donald W, McGlinchey, Michael J, Mornon, Jean-Paul, Thoreau, Etienne, Jaouen, Gerard

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Considerations of Thoreau’s Death, 1862 by Sophia E. Thoreau, Caroline Wells Healey Dall, Sophia Peabody Hawthorne, Sarah Alden Bradford Ripley

“…Profound joy mingles with my grief. I feel as if something very beautiful had happened, not death; although Henry is with us no longer, yet the memory of his…”
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Quantitative structure-activity relationship studies of RAR α, β, γ retinoid agonists by Douguet, Dominique, Thoreau, Etienne, Grassy, Gérard

“…Structure‐Activity Relationships have been established for 140 synthetic retinoid agonists. Retinoids, natural and synthetic analogues of vitamin A, are…”
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Comparison of three algorithms for the assignment of secondary structure in proteins: the advantages of a consensus assignment by Colloc'h, N, Etchebest, C, Thoreau, E, Henrissat, B, Mornon, J P

“…Accurate assignments of secondary structures in proteins are crucial for a useful comparison with theoretical predictions. Three major programs which…”
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Putative dimeric organization of nuclear receptor hormone-binding domains, deduced from hydrophobic cluster analysis by Mornon, J P, Thoreau, E, Rowlands, D, Callebaut, I, Moreau, G

“…2D hydrophobic cluster analysis (HCA) protein sequence processing, efficient at low levels of sequence identity, leads to a coherent scheme for the structural…”
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SOPHIA THOREAU, T. W. HIGGINSON, AND THE JOURNAL by Thoreau, S. E.

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