Search Results - "Thorborn, Daren"

New genetic predictors for abacavir tolerance in HLA-B57:01 positive individuals by Pavlos, Rebecca, Deshpande, Pooja, Chopra, Abha, Leary, Shay, Strautins, Kaija, Nolan, David, Thorborn, Daren, Shaefer, Mark, Rauch, Andri, Dunn, David, Montaner, Julio, Rachlis, Anita, Almeida, Coral-Ann, Choo, Linda, James, Ian, Redwood, Alec J., Li, Yueran, Gaudieri, Silvana, Mallal, Simon A., Phillips, Elizabeth J.

“…Abacavir hypersensitivity syndrome (ABC HSS) is strongly associated with carriage of human leukocyte antigen (HLA)-B*57:01, which has a 100% negative…”
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Intracellular cytokines may model immunoregulation of abacavir hypersensitivity in HIV-infected subjects by King, Deborah, Tomkins, Sarah, Waters, Anele, Easterbrook, Philippa J., Thurmond, Linda M., Thorborn, Daren E., Raffi, Francois, Kemeny, D. Mike, Vyakarnam, Annapurna

“…The clinical treatment of patients with HIV and adverse drug events may be enhanced by an understanding of the underlying mechanisms. About 4% of patients with…”
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HLA-B5701 Screening for Hypersensitivity to Abacavir by Mallal, Simon, Phillips, Elizabeth, Carosi, Giampiero, Molina, Jean-Michel, Workman, Cassy, Tomažič, Janez, Jägel-Guedes, Eva, Rugina, Sorin, Kozyrev, Oleg, Cid, Juan Flores, Hay, Phillip, Nolan, David, Hughes, Arlene, Hughes, Sara, Ryan, Susanna, Fitch, Nicholas, Thorborn, Daren, Benbow, Alastair

“…Hypersensitivity reactions to abacavir are tightly associated with HLA-B*5701. In this global, multicenter, prospective, randomized study, 1956 patients with…”
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PREDICT-1 (CNA106030): the first powered, prospective trial of pharmacogenetic screening to reduce drug adverse events by Hughes, Sara, Hughes, Arlene, Brothers, Cindy, Spreen, William, Thorborn, Daren

“…Pharmacogenetics (PGx) – the study of DNA variation in the human genome and the way this impacts the efficacy and safety of medicines – is becoming an…”
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Abacavir-Lamivudine-Zidovudine vs Indinavir-Lamivudine-Zidovudine in Antiretroviral-Naive HIV-Infected Adults: A Randomized Equivalence Trial by Staszewski, Schlomo, Keiser, Philip, Montaner, Julio, Raffi, Francois, Gathe, Joe, Brotas, Vitor, Hicks, Charles, Hammer, Scott M, Cooper, David, Johnson, Margaret, Tortell, Stephanie, Cutrell, Amy, Thorborn, Daren, Isaacs, Robin, Hetherington, Seth, Steel, Helen, Spreen, William, for the CNAAB3005 International Study Team

“…CONTEXT Abacavir, a nucleoside analogue, has demonstrated suppression of human immunodeficiency virus (HIV) replication alone and in combination therapy…”
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Early induction of leukemia inhibitor factor (LIF) in acute HIV-1 infection by TJERNLUND, Annelie, BARQASHO, Babilonia, NOWAK, Piotr, KINLOCH, Sabine, THORBORN, Daren, PERRIN, Luc, SÖNNERBORG, Anders, WALTHER-JALLOW, Lilian, ANDERSSON, Jan

“…Leukemia inhibitor factor (LIF) is thought to play a substantial role in protecting CD4 T cells in lymphoid tissues (LT) from infection by HIV-1. To…”
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HLA-B5701 Screening for Hypersensitivity to Abacavir by MALLAL, Simon, PHILLIPS, Elizabeth, HAY, Phillip, NOLAN, David, HUGHES, Sara, HUGHES, Arlene, RYAN, Susanna, FITCH, Nicholas, THORBORN, Daren, BENBOW, Alastair, CAROSI, Giampiero, MOLINA, Jean-Michel, WORKMAN, Cassy, TOMAZIC, Janez, JÄGEL-GUEDES, Eva, RUGINA, Sorin, KOZYREV, Oleg, CID, Juan Flores

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Polyamine and Thiol Metabolism in Trypanosoma granulosum: Similarities with Trypanosoma cruzi by Mastri, Calli, Thorborn, Daren E., Davies, Angela J., Ariyanayagam, Mark R., Hunter, Karl J.

“…Concentrations of free polyamines were investigated in Trypanosoma granulosum cultured in a semidefined medium containing traces of polyamines. Spermidine…”
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Uptake of putrescine by Trypanosoma granulosum by Mastri, C, Rytlewski, F, Thorborn, D, Davies, A J, Sappal, G

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The role of polyamines and related metabolites in the growth and morphology of two piscine trypanosomes by Thorborn, Daren E

“…In comparison with the vast amount of literature available on the trypanosomes of mammals, relatively little is understood of those of lower vertebrates,…”
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