Search Results - "Thongsin, Nontaphat"
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A three-dimensional immune-oncology model for studying in vitro primary human NK cell cytotoxic activity
Published in PloS one (21-03-2022)“…Immunotherapy has emerged as a promising therapeutic approach for treating several forms of cancer. Adoptive cell transfer of immune cells, such as natural…”
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A precise gene delivery approach for human induced pluripotent stem cells using Cas9 RNP complex and recombinant AAV6 donor vectors
Published in PloS one (07-07-2022)“…Genome editing in human induced pluripotent stem cells (hiPSCs) offers a potential tool for studying gene functions in disease models and correcting genetic…”
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Generation of a homozygous TIGIT gene knockout (TIGIT−/−) human iPSC line (MUSIi001-A-3) using CRISPR/Cas9 system
Published in Stem cell research (01-12-2024)“…Adoptive cell therapy for solid cancers involves enhancing and reinfusing immune cells to target tumor cells. The advancement of induced pluripotent stem cell…”
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Generation of B2M bi-allelic knockout human induced pluripotent stem cells (MUSIi001-A-1) using a CRISPR/Cas9 system
Published in Stem cell research (01-10-2021)“…Allogeneic cell-based therapy is emerging as a promising approach in regenerative medicine. However, rejection of allograft due to mismatch of human leukocyte…”
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CRISPR-Cas9-mediated disruption of B2M and CIITA genes eliminates HLA class I and II expression in human induced pluripotent stem cells (MUSIi001-A-2)
Published in Stem cell research (01-09-2023)“…Cell-based therapy offers great promise for treating degenerative diseases. Although autologous cell-based therapy is ideal, it may be impractical due to the…”
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A live single-cell reporter system reveals drug-induced plasticity of a cancer stem cell-like population in cholangiocarcinoma
Published in Scientific reports (30-09-2024)“…Cancer stem cells (CSC) play an important role in carcinogenesis and are acknowledged to be responsible for chemoresistance in cholangiocarcinoma (CCA)…”
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Genetic correction of haemoglobin E in an immortalised haemoglobin E/beta-thalassaemia cell line using the CRISPR/Cas9 system
Published in Scientific reports (16-09-2022)“…β-thalassaemia is one of the most common genetic blood diseases worldwide with over 300 mutations in the HBB gene affecting red blood cell functions. Recently,…”
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Phenotypic and transcriptomic profiling of induced pluripotent stem cell (iPSC)-derived NK cells and their cytotoxicity against cancers
Published in Stem cell research & therapy (13-11-2024)“…Adoptive immunotherapy using natural killer (NK) cells has attracted considerable interest in numerous clinical trials targeting both hematological and solid…”
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Generation of an induced pluripotent stem cell line (MUSIi014-A) from an affected member of a family with autosomal dominant diabetes carrying p.L475P mutation in ZYG11A gene associated with a cell cycle arrest in beta-cell
Published in Stem cell research (01-04-2022)“…•A novel ZYG11A mutation (p.L475P) associated with hyperglycemia has been identified as a cause of cell cycle arrest and retardation of beta-cell growth.•We…”
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CRISPR/Cas9-Mediated GFP Reporter Knock-in in K562 and Raji Cell Lines for Tracking Immune Cell Killing Assay
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Cell-mediated cytotoxicity plays an important role in several fundamental immunological processes and is crucial for biological evaluation in in vitro studies…”
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11
A three-dimensional immune-oncology model for studying in vitro primary human NK cell cytotoxic activity
Published in PloS one (01-01-2022)“…Immunotherapy has emerged as a promising therapeutic approach for treating several forms of cancer. Adoptive cell transfer of immune cells, such as natural…”
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Journal Article -
12
Doxorubicin sensitizes breast cancer cells to natural killer cells in connection with increased Fas receptors
Published in International journal of molecular medicine (01-03-2022)“…Breast cancer (BC) is the most common cancer in women. Although standard treatments are successful in patients with BC diagnosed at an early stage, an…”
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High diversity of Blastocystis subtypes isolated from asymptomatic adults living in Chiang Rai, Thailand
Published in Infection, genetics and evolution (01-11-2018)“…Blastocystis is a common and broadly distributed microbial eukaryote inhabiting the gut of humans and other animals. The genetic diversity of Blastocystis is…”
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