Search Results - "Thonar, Eugene M A"

Platelet-rich plasma (PRP) stimulates the extracellular matrix metabolism of porcine nucleus pulposus and anulus fibrosus cells cultured in alginate beads by AKEDA, Koji, AN, Howard S, PICHIKA, Rajeswari, ATTAWIA, Mohamed, THONAR, Eugene J.-M. A, LENZ, Mary Ellen, UCHIDA, Atsumasa, MASUDA, Koichi

“…In vitro assessment of the effects of platelet-rich plasma on the extracellular matrix metabolism of porcine intervertebral disc cells. To determine whether…”
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Recombinant human osteogenic protein-1 upregulates proteoglycan metabolism of human anulus fibrosus and nucleus pulposus cells by Imai, Yoshiyuki, Miyamoto, Kei, An, Howard S, Thonar, Eugene J-M A, Andersson, Gunnar B J, Masuda, Koichi

“…In vitro assessment of the effects of recombinant human osteogenic protein-1 (rhOP-1) on the proteoglycan metabolism of human intervertebral disc cells. To…”
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A novel two-step method for the formation of tissue-engineered cartilage by mature bovine chondrocytes: the alginate-recovered-chondrocyte (ARC) method by Masuda, Koichi, Sah, Robert L, Hejna, Michael J, Thonar, Eugene J.-M.A

“…Most attempts to tissue-engineer cartilage have involved seeding of cultured cells into a biological or synthetic scaffold. We have developed a novel two-step…”
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Comparative effects of bone morphogenetic proteins and sox9 overexpression on extracellular matrix metabolism of bovine nucleus pulposus cells by YEJIA ZHANG, AN, Howard S, THONAR, Eugene J.-M. A, CHUBINSKAYA, Susan, HE, Tong-Chuan, PHILLIPS, Frank M

“…An in vitro biologic study of the effects of adenovirus expressing bone morphogenetic proteins (BMPs) and adenovirus expressing Sox9 on extracellular matrix…”
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Cell Therapy Using Articular Chondrocytes Overexpressing BMP-7 or BMP-10 in a Rabbit Disc Organ Culture Model by YEJIA ZHANG, PHILLIPS, Frank M, THONAR, Eugene J.-M. A, OEGEMA, Theodore, AN, Howard S, ROMAN-BIAS, Jorge A, HE, Tong-Chuan, ANDERSON, D. Greg

“…Rabbit knee articular chondrocytes overexpressing human growth factors were injected into cultured intervertebral disc explants. Survival of the injected cells…”
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Age-Related Changes in the Extracellular Matrix of Nucleus Pulposus and Anulus Fibrosus of Human Intervertebral Disc by SINGH, Kern, MASUDA, Koichi, THONAR, Eugene J-M. A, AN, Howard S, CS-SZABO, Gabriella

“…To characterize age-related changes in the matrix of human intervertebral disc (IVD) specimens, human specimens from the third to the eighth decade of life…”
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Transduced bovine articular chondrocytes affect the metabolism of cocultured nucleus pulposus cells in vitro : Implications for chondrocyte transplantation into the intervertebral disc by YEJIA ZHANG, ZHEN LI, THONAR, Eugene J.-M. A, AN, Howard S, HE, Tong-Chuan, PIETRYLA, Daniel, PHILLIPS, Frank M

“…Biologic study on the effects of coculture of bovine articular chondrocytes transduced ex vivo with genes expressing bone morphogenetic proteins (BMPs) on…”
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Tensile mechanical properties of bovine articular cartilage: variations with growth and relationships to collagen network components by Williamson, Amanda K, Chen, Albert C, Masuda, Koichi, Thonar, Eugene J.-M.A, Sah, Robert L

“…One approach to repairing articular defects is to regenerate cartilage by recapitulating the changes that occur during fetal and postnatal growth into…”
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Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degeneration by CS-SZABO, Gabriella, RAGASA-SAN JUAN, Deborah, TURUMELLA, Vani, MASUDA, Koichi, THONAR, Eugene J-M. A, AN, Howard S

“…This study correlates the mRNA and protein levels of large and small proteoglycans with the morphologic grade of degeneration. To investigate changes in mRNA…”
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The use of intra-articular Na-hyaluronate as a potential chondroprotective device in experimentally induced acute articular cartilage injury and repair in rabbits by Williams, James M, Rayan, Vineeta, Sumner, D.Rick, Thonar, Eugene J.-M.A

“…Objective: This study examined if viscosupplementation from intra-articular administration of a commercially available form of hyaluronan (HA) could promote…”
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Osteogenic protein-1 enhances matrix replenishment by intervertebral disc cells previously exposed to interleukin-1 by Takegami, Kenji, Thonar, Eugene J M A, An, Howard S, Kamada, Hiroshi, Masuda, Koichi

“…A study of the mechanisms involved in matrix repair by intervertebral disc cells cultured in alginate gel was performed. To determine the effects of osteogenic…”
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Mechanisms of cartilage growth: Modulation of balance between proteoglycan and collagen in vitro using chondroitinase ABC by Asanbaeva, Anna, Masuda, Koichi, Thonar, Eugene J.‐M. A., Klisch, Stephen M., Sah, Robert L.

“…Objective To examine the cartilage growth–associated effects of a disruption in the balance between the swelling pressure of glycosaminoglycans (GAGs) and the…”
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Repair of articular cartilage injury following intra-articular chymopapain-induced matrix proteoglycan loss by Williams, J M, Ongchi, D R, Thonar, E J

“…The intra-articular injection of 0.02, 0.2, or 2.0 mg of chymopapain (CP) into the knee of adolescent rabbits caused the loss of more than 50% of the…”
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Transplantation of Goat Bone Marrow Stromal Cells to the Degenerating Intervertebral Disc in a Goat Disc Injury Model by YEJIA ZHANG, DRAPEAU, Susan, AN, Howard S, THONAR, Eugene J. M. A, ANDERSON, D. Greg

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Exposure to pulsed low intensity ultrasound stimulates extracellular matrix metabolism of bovine intervertebral disc cells cultured in alginate beads by MIYAMOTO, Kei, AN, Howard S, SAH, Robert L, AKEDA, Koji, OKUMA, Masahiko, OTTEN, Lori, THONAR, Eugene J.-M. A, MASUDA, Koichi

“…In vitro study on the effects of pulsed low intensity ultrasound on the cellular metabolism of bovine intervertebral disc cells. To determine whether pulsed…”
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Differential effects of fibronectin fragment on proteoglycan metabolism by intervertebral disc cells : A comparison with articular chondrocytes by AOTA, Yoichi, AN, Howard S, HOMANDBERG, Gene, THONAR, Eugene J. M.-A, ANDERSSON, Gunnar B. J, PICHIKA, Rajeswari, MASUDA, Koichi

“…This in vitro study used the alginate bead culture system to probe for differences in the effects of fibronectin fragment on cell proliferation and…”
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Culture of Chondrocytes in Alginate Gel: Variations in Conditions of Gelation Influence the Structure of the Alginate Gel, and the Arrangement and Morphology of Proliferating Chondrocytes by Margaret B. Aydelotte, Eugene J. -M. A. Thonar, Mollenhauer, Jürgen, Johannes Flechtenmacher

“…Sodium alginate, which gels in the presence of calcium ions, is commonly used for culture of anchorage-independent cells, such as chondrocytes. Normally, the…”
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Intradiscal administration of osteogenic protein-1 increases intervertebral disc height and proteoglycan content in the nucleus pulposus in normal adolescent rabbits by An, Howard S, Takegami, Kenji, Kamada, Hiroshi, Nguyen, Cahn M, Thonar, Eugene J-M A, Singh, Kern, Andersson, Gunnar B, Masuda, Koichi

“…A study of the disc height and biochemical changes in the rabbit intervertebral disc after injection of osteogenic protein-1 into the nucleus pulposus. To…”
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Biological repair of intervertebral disc by An, Howard S, Thonar, Eugene J-M A, Masuda, Koichi

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Implant Design Affects Markers of Bone Resorption and Formation in Total Hip Replacement by Qureshi, Abid A., Virdi, Amarjit S., Didonna, Michael L., Jacobs, Joshua J., Masuda, Koichi, Paprosky, Wayne P., Thonar, Eugene J. M. A., Sumner, Dale R.

“…Concentrations of the bone resorption markers pyridinoline and deoxypyridinoline and the bone formation marker osteocalcin were measured in 24‐h urine…”
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