Search Results - "Thomson, Errol M."

Ambient air pollution exposure and emergency department visits for substance abuse by Szyszkowicz, Mieczysław, Thomson, Errol M, Colman, Ian, Rowe, Brian H

“…There is growing evidence supporting the notion that exposure to air pollution can contribute to cognitive and psychiatric disorders, including depression and…”
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Modulation by Ozone of Glucocorticoid-Regulating Factors in the Lungs in Relation to Stress Axis Reactivity by Thomas, Jith, Thomson, Errol M.

“…Exposure to air pollutants increases levels of circulating glucocorticoid stress hormones that exert profound effects relevant to health and disease. However,…”
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Metabolic, stress, and inflammatory biomarker responses to glucose administration in Fischer-344 rats: intraperitoneal vs. oral delivery by Pilon, Shinjini, Holloway, Alison C., Thomson, Errol M.

“…Metabolic effects of anthropogenic chemicals are a focus of environmental health research due to the significant public health implications. Conventional…”
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Cardiovascular and inflammatory mechanisms in healthy humans exposed to air pollution in the vicinity of a steel mill by Kumarathasan, Premkumari, Vincent, Renaud, Blais, Erica, Bielecki, Agnieszka, Guénette, Josée, Filiatreault, Alain, Brion, Orly, Cakmak, Sabit, Thomson, Errol M, Shutt, Robin, Kauri, Lisa Marie, Mahmud, Mamun, Liu, Ling, Dales, Robert

“…There is a paucity of mechanistic information that is central to the understanding of the adverse health effects of source emission exposures. To identify…”
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Concordance between In Vitro and In Vivo Relative Toxic Potencies of Diesel Exhaust Particles from Different Biodiesel Blends by Karthikeyan, Subramanian, Breznan, Dalibor, Thomson, Errol M, Blais, Erica, Vincent, Renaud, Kumarathasan, Premkumari

“…Diesel exhaust particles (DEPs) contribute to air pollution exposure-related adverse health impacts. Here, we examined in vitro, and in vivo toxicities of DEPs…”
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Impact of Superoxide Dismutase Mimetic AEOL 10150 on the Endothelin System of Fischer 344 Rats by Ganesh, Devi, Kumarathasan, Prem, Thomson, Errol M, St-Germain, Carly, Blais, Erica, Crapo, James, Vincent, Renaud

“…Endothelin-1 is a potent vasoconstrictor and mitogenic peptide involved in the regulation of vasomotor tone and maintenance of blood pressure. Oxidative stress…”
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Application of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9 by Yauk, Carole L., Buick, Julie K., Williams, Andrew, Swartz, Carol D., Recio, Leslie, Li, Heng-Hong, Fornace Jr, Albert J., Thomson, Errol M., Aubrecht, Jiri

“…In vitro transcriptional signatures that predict toxicities can facilitate chemical screening. We previously developed a transcriptomic biomarker (known as…”
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Mapping acute systemic effects of inhaled particulate matter and ozone: multiorgan gene expression and glucocorticoid activity by Thomson, Errol M, Vladisavljevic, Djordje, Mohottalage, Susantha, Kumarathasan, Prem, Vincent, Renaud

“…Recent epidemiological studies have demonstrated associations between air pollution and adverse effects that extend beyond respiratory and cardiovascular…”
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Stress hormones as potential mediators of air pollutant effects on the brain: Rapid induction of glucocorticoid-responsive genes by Thomson, Errol M., Filiatreault, Alain, Guénette, Josée

“…Air pollution is associated with adverse effects on brain health including cognitive decline, dementia, anxiety, depression, and suicide. While toxicological…”
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Sex-difference in air pollution-related acute circulatory and respiratory mortality and hospitalization by Shin, Hwashin H., Maquiling, Aubrey, Thomson, Errol M., Park, In-Woo, Stieb, Dave M., Dehghani, Parvin

“…Numerous studies have estimated adverse effects of short-term exposure to ambient air pollution on public health. Few have focused on sex-differences, and…”
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Randomized Cross-Over Study of In-Vehicle Cabin Air Filtration, Air Pollution Exposure, and Acute Changes to Heart Rate Variability, Saliva Cortisol, and Cognitive Function by Mallach, Gary, Shutt, Robin, Thomson, Errol M, Valcin, Frédéric, Kulka, Ryan, Weichenthal, Scott

“…To determine how traffic-related air pollution (TRAP) exposures affect commuter health, and whether cabin air filtration (CAF) can mitigate exposures, we…”
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Effects of scanning sensitivity and multiple scan algorithms on microarray data quality by Williams, Andrew, Thomson, Errol M

“…Maximizing the utility of DNA microarray data requires optimization of data acquisition through selection of an appropriate scanner setting. To increase the…”
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Modulation of insulin signaling pathway genes by ozone inhalation and the role of glucocorticoids: A multi-tissue analysis by Rose, Mercedes, Filiatreault, Alain, Williams, Andrew, Guénette, Josée, Thomson, Errol M.

“…Air pollution is associated with increased risk of metabolic diseases including type 2 diabetes, of which dysregulation of the insulin-signaling pathway is a…”
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Ozone increases plasma kynurenine-tryptophan ratio and impacts hippocampal serotonin receptor and neurotrophic factor expression: Role of stress hormones by Rose, Mercedes, Filiatreault, Alain, Guénette, Josée, Williams, Andrew, Thomson, Errol M.

“…Air pollution is associated with adverse impacts on the brain, including cognitive decline and increased incidence of dementia, depression and anxiety;…”
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Corticosterone determination in bronchoalveolar lavage fluid and its relationship to free and total plasma corticosterone by Thomas, Jith, Thomson, Errol M.

“…Endogenous glucocorticoids modulate airway and lung inflammation in various respiratory diseases and after exposure to airborne contaminants. Although…”
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Residential greenness and indicators of stress and mental well-being in a Canadian national-level survey by Crouse, Dan L., Pinault, Lauren, Christidis, Tanya, Lavigne, Eric, Thomson, Errol M., Villeneuve, Paul J.

“…Residential proximity to greenness in urban areas has been shown to confer a number of health benefits, including improved mental health. We investigated…”
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Establishing an air-liquid interface exposure system for exposure of lung cells to gases by Guénette, Josée, Breznan, Dalibor, Thomson, Errol M

“…Growing interest in non-animal-based models has led to the development of devices to expose cells to airborne substances. Cells/tissues grown at the air-liquid…”
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A high throughput screening assay for human Thyroperoxidase inhibitors by Dong, Hongyan, Friedman, Katie Paul, Filiatreault, Alain, Thomson, Errol M., Wade, Michael G.

“…Rapid, human relevant assays are needed to assess potential hazards of the many chemicals in commerce. An assay of thyroid peroxidase (TPO) inhibition, using…”
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Correlation between Saliva and Plasma Levels of Endothelin Isoforms ET-1, ET-2, and ET-3 by Gurusankar, Roma, Kumarathasan, Prem, Saravanamuthu, Anusha, Thomson, Errol M., Vincent, Renaud

“…Although saliva endothelins are emerging as valuable noninvasive cardiovascular biomarkers, reports on the relationship between isoforms in saliva and plasma…”
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Exposure to Diesel Exhaust and Plasma Cortisol Response: A Randomized Double-Blind Crossover Study by Thomson, Errol M, Filiatreault, Alain, Williams, Andrew, Rider, Christopher F, Carlsten, Chris

“…Experimental work has demonstrated that glucocorticoid stress hormones are potential mediators of pulmonary and systemic pollutant effects of both particulate…”
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