Search Results - "Thomson, Daniel W."

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  1. 1

    lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs by Quek, Xiu Cheng, Thomson, Daniel W, Maag, Jesper L V, Bartonicek, Nenad, Signal, Bethany, Clark, Michael B, Gloss, Brian S, Dinger, Marcel E

    Published in Nucleic acids research (28-01-2015)
    “…Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function…”
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  2. 2

    On measuring miRNAs after transient transfection of mimics or antisense inhibitors by Thomson, Daniel W, Bracken, Cameron P, Szubert, Jan M, Goodall, Gregory J

    Published in PloS one (24-01-2013)
    “…The ability to alter microRNA (miRNA) abundance is crucial for studying miRNA function. To achieve this there is widespread use of both exogenous…”
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    Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin by Thomson, Daniel W, Pillman, Katherine A, Anderson, Matthew L, Lawrence, David M, Toubia, John, Goodall, Gregory J, Bracken, Cameron P

    Published in Nucleic acids research (01-01-2015)
    “…High-throughput sequencing reveals an abundance of microRNA-sized fragments derived from larger non-coding RNAs. Roles for these small RNAs in gene silencing…”
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  5. 5

    Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage by Bracken, Cameron P., Szubert, Jan M., Mercer, Tim R., Dinger, Marcel E., Thomson, Daniel W., Mattick, John S., Michael, Michael Z., Goodall, Gregory J.

    Published in Nucleic acids research (01-07-2011)
    “…The Ago2 component of the RNA-induced silencing complex (RISC) is an endonuclease that cleaves mRNAs that base pair with high complementarity to RISC-bound…”
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  6. 6

    Experimental strategies for microRNA target identification by Thomson, Daniel W, Bracken, Cameron P, Goodall, Gregory J

    Published in Nucleic acids research (01-09-2011)
    “…MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression in most biological processes. They act by guiding the RNAi-induced silencing complex…”
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  7. 7

    Endogenous microRNA sponges: evidence and controversy by Thomson, Daniel W., Dinger, Marcel E.

    Published in Nature reviews. Genetics (01-05-2016)
    “…Key Points The competitive endogenous RNA (ceRNA) hypothesis posits that transcripts with shared microRNA binding sites compete for post-transcriptional…”
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  8. 8

    Aberrant RAG-mediated recombination contributes to multiple structural rearrangements in lymphoid blast crisis of chronic myeloid leukemia by Thomson, Daniel W., Shahrin, Nur Hezrin, Wang, Paul P. S., Wadham, Carol, Shanmuganathan, Naranie, Scott, Hamish S., Dinger, Marcel E., Hughes, Timothy P., Schreiber, Andreas W., Branford, Susan

    Published in Leukemia (01-08-2020)
    “…Blast crisis of chronic myeloid leukemia is associated with poor survival and the accumulation of genomic lesions. Using whole-exome and/or RNA sequencing of…”
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