Search Results - "Thomson, Carolyn"

Peripheral inflammation is associated with remote global gene expression changes in the brain by Thomson, Carolyn A, McColl, Alison, Cavanagh, Jonathan, Graham, Gerard J

“…Although the central nervous system (CNS) was once considered an immunologically privileged site, in recent years it has become increasingly evident that cross…”
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Microbiota and Microglia Interactions in ASD by Davoli-Ferreira, Marcela, Thomson, Carolyn A., McCoy, Kathy D.

“…Autism spectrum disorders (ASD) are serious, highly variable neurodevelopmental disorders, commonly characterized by the manifestation of specific behavioral…”
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Sustained exposure to systemic endotoxin triggers chemokine induction in the brain followed by a rapid influx of leukocytes by Thomson, Carolyn A, McColl, Alison, Graham, Gerard J, Cavanagh, Jonathan

“…Recent years have seen an explosion of research pertaining to biological psychiatry, yet despite subsequent advances in our understanding of neuroimmune…”
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Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis by Scott, Nicholas A, Andrusaite, Anna, Andersen, Peter, Lawson, Melissa, Alcon-Giner, Cristina, Leclaire, Charlotte, Caim, Shabhonam, Le Gall, Gwenaelle, Shaw, Tovah, Connolly, James P R, Roe, Andrew J, Wessel, Hannah, Bravo-Blas, Alberto, Thomson, Carolyn A, Kästele, Verena, Wang, Ping, Peterson, Daniel A, Bancroft, Allison, Li, Xuhang, Grencis, Richard, Mowat, Allan McI, Hall, Lindsay J, Travis, Mark A, Milling, Simon W F, Mann, Elizabeth R

“…Macrophages in the healthy intestine are highly specialized and usually respond to the gut microbiota without provoking an inflammatory response. A breakdown…”
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Microbiota alters the metabolome in an age- and sex- dependent manner in mice by Brown, Kirsty, Thomson, Carolyn A., Wacker, Soren, Drikic, Marija, Groves, Ryan, Fan, Vina, Lewis, Ian A., McCoy, Kathy D.

“…Commensal bacteria are major contributors to mammalian metabolism. We used liquid chromatography mass spectrometry to study the metabolomes of germ-free,…”
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Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization by Ignacio, Aline, Shah, Kathleen, Bernier-Latmani, Jeremiah, Köller, Yasmin, Coakley, Gillian, Moyat, Mati, Hamelin, Romain, Armand, Florence, Wong, Nick C., Ramay, Hena, Thomson, Carolyn A., Burkhard, Regula, Wang, Haozhe, Dufour, Antoine, Geuking, Markus B., McDonald, Braedon, Petrova, Tatiana V., Harris, Nicola L., McCoy, Kathy D.

“…The intestine harbors a large population of resident eosinophils, yet the function of intestinal eosinophils has not been explored. Flow cytometry and…”
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The Impact of Maternal Microbes and Microbial Colonization in Early Life on Hematopoiesis by McCoy, Kathy D, Thomson, Carolyn A

“…All body surfaces are colonized by microbes, which occurs through a dynamic process over the first few years of life. Initial colonizing microbes are…”
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From germ-free to wild: modulating microbiome complexity to understand mucosal immunology by Thomson, Carolyn A., Morgan, Sydney C., Ohland, Christina, McCoy, Kathy D.

“…The gut microbiota influences host responses at practically every level, and as research into host-microbe interactions expands, it is not surprising that we…”
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Immunological roles of intestinal mesenchymal cells by Thomson, Carolyn A., Nibbs, Robert J., McCoy, Kathy D., Mowat, Allan Mcl

“…Summary The intestine is continuously exposed to an enormous variety and quantity of antigens and innate immune stimuli derived from both pathogens and…”
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Not All Lymph Nodes Are Created Equal by Thomson, Carolyn A., McCoy, Kathy D.

“…Appropriate priming of tolerogenic or effector immune responses is crucial for intestinal homeostasis. Recently in Nature, Esterházy et al. (2019) reveal how…”
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Using Precisely Defined in vivo Microbiotas to Understand Microbial Regulation of IgE by Wyss, Madeleine, Brown, Kirsty, Thomson, Carolyn A, Koegler, Mia, Terra, Fernanda, Fan, Vina, Ronchi, Francesca, Bihan, Dominique, Lewis, Ian, Geuking, Markus B, McCoy, Kathy D

“…Early life exposure to microbes plays an important role in immune system development. Germ-free mice, or mice colonized with a low-diversity microbiota,…”
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Vascular traffic control of neutrophil recruitment to the liver by microbiota-endothelium crosstalk by Zucoloto, Amanda Z., Schlechte, Jared, Ignacio, Aline, Thomson, Carolyn A., Pyke, Shannon, Yu, Ian-ling, Geuking, Markus B., McCoy, Kathy D., Yipp, Bryan G., Gillrie, Mark R., McDonald, Braedon

“…During bloodstream infections, neutrophils home to the liver as part of an intravascular immune response to eradicate blood-borne pathogens, but the mechanisms…”
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TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain by McColl, Alison, Thomson, Carolyn A, Nerurkar, Louis, Graham, Gerard J, Cavanagh, Jonathan

“…The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the…”
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Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators by Thomson, Carolyn A, van de Pavert, Serge A, Stakenborg, Michelle, Labeeuw, Evelien, Matteoli, Gianluca, Mowat, Allan McI, Nibbs, Robert J B

“…Atypical chemokine receptors (ACKRs) are expressed by discrete populations of stromal cells at specific anatomical locations where they control leukocyte…”
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Proinflammatory Role of Monocyte-Derived CX3CR1int Macrophages in Helicobacter hepaticus-Induced Colitis by Bain, Calum C, Oliphant, Christopher J, Thomson, Carolyn A, Kullberg, Marika C, Mowat, Allan M

“…Cells of the monocyte/macrophage lineage play important roles in the pathogenesis of inflammatory bowel diseases, but they are also present in the normal…”
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Intestinal colonization regulates systemic anti-commensal immune sensitivity and hyperreactivity by Burkhard, Regula, Koegler, Mia, Brown, Kirsty, Wilson, Kirsten, Mager, Lukas F, Zucoloto, Amanda Z, Thomson, Carolyn, Hebbandi Nanjundappa, Roopa, Skalosky, Isla, Ahmadi, Shokouh, McDonald, Braedon, Geuking, Markus B

“…Healthy host-microbial mutualism with our intestinal microbiota relies to a large degree on compartmentalization and careful regulation of adaptive mucosal and…”
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Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection by Hulme, Heather E., Meikle, Lynsey M., Wessel, Hannah, Strittmatter, Nicole, Swales, John, Thomson, Carolyn, Nilsson, Anna, Nibbs, Robert J. B., Milling, Simon, Andren, Per E., Mackay, C. Logan, Dexter, Alex, Bunch, Josephine, Goodwin, Richard J. A., Burchmore, Richard, Wall, Daniel M.

“…Salmonella Typhimurium causes a self-limiting gastroenteritis that may lead to systemic disease. Bacteria invade the small intestine, crossing the intestinal…”
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Proinflammatory Role of Monocyte-Derived CX3CR1 int Macrophages in Helicobacter hepaticus-Induced Colitis by Bain, Calum C, Oliphant, Christopher J, Thomson, Carolyn A, Kullberg, Marika C, Mowat, Allan M

“…Cells of the monocyte/macrophage lineage play important roles in the pathogenesis of inflammatory bowel diseases, but they are also present in the normal…”
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Addressing medical resident mistreatment: A resident-centred approach by Sahiti, Qëndresa, Shearer, Cindy, Thomson, Carolyn, Sutherland, Lisa, Bowes, David

“…Mistreatment negatively impacts the wellbeing of medical learners and is related to worse patient outcomes and team functioning. Resident perspectives on…”
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106 “Resilience by Design” - Description of a Pilot Radiation Oncology Wellness Program by Dahn, Hannah, Thomson, Carolyn, Bowes, David, Ilie, Gabriela, Rutledge, Rob

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