Search Results - "Thomson, Allan D."
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THE NATURAL HISTORY AND PATHOPHYSIOLOGY OF WERNICKE'S ENCEPHALOPATHY AND KORSAKOFF'S PSYCHOSIS
Published in Alcohol and alcoholism (Oxford) (01-03-2006)“…Aims: To identify the early clinical indications of thiamine deficiency and to understand the factors involved in the development of the amnesic state in…”
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The Korsakoff Syndrome: Clinical Aspects, Psychology and Treatment
Published in Alcohol and alcoholism (Oxford) (01-03-2009)“…Aims: The Korsakoff syndrome is a preventable memory disorder that usually emerges (although not always) in the aftermath of an episode of Wernicke's…”
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Genetic and environmental interplay in risky drinking in adolescents: a literature review
Published in Alcohol and alcoholism (Oxford) (01-03-2014)“…The aim of the study was to review recent research on the interplay between genes, environment and epigenetic factors in risky drinking in adolescents and the…”
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SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke–Korsakoff’s Syndrome
Published in Alcohol and alcoholism (Oxford) (10-09-2022)“…Abstract Aims Wernicke–Korsakoff syndrome (WKS) is commonly associated with chronic alcohol misuse, a condition known to have multiple detrimental effects on…”
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Mechanisms of Vitamin Deficiency in Chronic Alcohol Misusers and the Development of the Wernicke-Korsakoff Syndrome
Published in Alcohol and alcoholism (Oxford) (01-05-2000)“…The classic signs of vitamin deficiency only occur in states of extreme depletion and are unreliable indicators for early treatment or prophylaxis of alcoholic…”
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Time to Act on the Inadequate Management of Wernicke's Encephalopathy in the UK
Published in Alcohol and alcoholism (Oxford) (2013)“…Wernicke's encephalopathy (WE) is a serious medical emergency whose pathogenesis is well understood and reviewed in this paper. Summarizing the evidence for…”
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BNF recommendations for the treatment of Wernicke's encephalopathy: lost in translation?
Published in Alcohol and alcoholism (Oxford) (01-07-2013)Get full text
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THE ROYAL COLLEGE OF PHYSICIANS REPORT ON ALCOHOL: GUIDELINES FOR MANAGING WERNICKE’S ENCEPHALOPATHY IN THE ACCIDENT AND EMERGENCY DEPARTMENT
Published in Alcohol and alcoholism (Oxford) (01-11-2002)“…The Royal College of Physicians (London) recently published its latest report on alcohol misuse entitled ‘Alcohol — Can the NHS Afford It?’. Part of this…”
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THE TREATMENT OF PATIENTS AT RISK OF DEVELOPING WERNICKE'S ENCEPHALOPATHY IN THE COMMUNITY
Published in Alcohol and alcoholism (Oxford) (01-03-2006)“…Aim: To review the process of identifying alcohol-dependent patients at risk of developing Wernicke's encephalopathy (WE) in the community, and prophylactic…”
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Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population
Published in Addiction biology (01-05-2015)“…Certain single nucleotide polymorphisms (SNPs) in genes encoding alcohol dehydrogenase (ADH) enzymes confer a significant protective effect against alcohol…”
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Phenotypic heterogeneity in study populations may significantly confound the results of genetic association studies on alcohol dependence
Published in Psychiatric genetics (01-12-2015)“…BACKGROUNDThe interpretation of genetic studies on alcohol dependence may be confounded by the co-occurrence of substance dependence, psychiatric disorders and…”
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The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder
Published in Psychiatric genetics (01-12-2014)“…We previously reported that a Kozak sequence variant in the metabotropic glutamate receptor 3 gene (GRM3), rs148754219, is associated with bipolar disorder…”
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The importance of alcohol misuse, malnutrition and genetic susceptibility on brain growth and plasticity
Published in Neuroscience and biobehavioral reviews (2007)“…The “dyad: alcoholic mother and foetus” is a very complex entity in which several elements such as genes, metabolism, diet, drugs and social habits play a role…”
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Wernicke's Encephalopathy revisited
Published in Alcohol and alcoholism (Oxford) (01-03-2008)“…Aims: A translation into English of the case history section of Carl Wernicke's original manuscript of 1881, with a discussion on its relevance for clinicians…”
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Wernicke's encephalopathy: ‘plus ca change, plus c'est la meme chose’
Published in Alcohol and alcoholism (Oxford) (01-03-2008)“…Aims: To develop clinical guidelines to identify individuals who misuse alcohol and are at risk of developing Wernicke's Encephalopathy (WE). Method:…”
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Molecular Genetics of Alcohol-Related Brain Damage
Published in Alcohol and alcoholism (Oxford) (01-03-2009)“…Aims: In the scientific literature it has been repeatedly hypothesized that there is a heritable susceptibility to thiamine deficiency comparable to other…”
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Biomarkers for Detecting Thiamine Deficiency—Improving Confidence and Taking a Comprehensive History are also Important
Published in Alcohol and alcoholism (Oxford) (01-03-2010)Get full text
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Evidence for genetic susceptibility to the alcohol dependence syndrome from the thiamine transporter 2 gene solute carrier SLC19A3
Published in Psychiatric genetics (01-06-2014)“…The risk for developing the alcohol dependence syndrome (ADS) has a substantial genetic component. The human thiamine transporter protein 2 (hTHTR2) is encoded…”
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Lack of allelic association between markers at the DRD2 and ANKK1 gene loci with the alcohol-dependence syndrome and criminal activity
Published in Psychiatric genetics (01-12-2011)Get full text
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Introduction to This Issue: The Seven Ages of Man … (or Woman)
Published in Alcohol and alcoholism (Oxford) (01-03-2009)Get full text
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