Search Results - "Thomsen, Lindy L"

Uric acid promotes tumor immune rejection by HU, De-En, MOORE, Alistair M, THOMSEN, Lindy L, BRINDLE, Kevin M

“…Uric acid released from dying cells has been shown recently to act as a danger signal for the immune system, stimulating dendritic cell maturation and…”
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Induced recruitment of NK cells to lymph nodes provides IFN-γ for TH1 priming by Martín-Fontecha, Alfonso, Thomsen, Lindy L, Brett, Sara, Gerard, Craig, Lipp, Martin, Lanzavecchia, Antonio, Sallusto, Federica

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Instruction of naive CD4+ T cells by polarized CD4+ T cells within dendritic cell clusters by Creusot, Rémi J., Biswas, Jason S., Thomsen, Lindy L., Tite, John P., Mitchison, N. Avrion, Chain, Benjamin M.

“…Cooperation between CD4+ T cells can enhance the response and modulate the cytokine profile, and defining these parameters has become a major issue for…”
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Role of nitric oxide in tumour progression: lessons from human tumours by Thomsen, L L, Miles, D W

“…Varied cellular expression and localisation of nitric oxide synthase (NOS) isoforms has been shown in human cancers, including tumours of the breast, ovary,…”
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Imiquimod and resiquimod in a mouse model: adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery by Thomsen, Lindy L., Topley, Peter, Daly, Maria G., Brett, Sara J., Tite, John P.

“…Imiquimod, an immune response modifier and inducer of cytokines in vitro and in vivo, has been shown to have potent antiviral and antitumour activity and to…”
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Immune-response profiles induced by human immunodeficiency virus type 1 vaccine DNA, protein or mixed-modality immunization: increased protection from pathogenic simian human immunodeficiency virus viraemia with protein/DNA combination by Koopman, Gerrit, Mortier, Daniella, Hofman, Sam, Mathy, Nathalie, Koutsoukos, Marguerite, Ertl, Peter, Overend, Phil, van Wely, Cathy, Thomsen, Lindy L, Wahren, Britta, Voss, Gerald, Heeney, Jonathan L

“…1 Department of Virology, Biomedical Primate Research Center (BPRC), 2288 GH Rijswijk, The Netherlands 2 GlaxoSmithKline Biologicals, Rixensart, Belgium 3…”
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Nitric oxide synthase activity in human gynecological cancer by THOMSEN, L. L, LAWTON, F. G, KNOWLES, R. G, BEESLEY, J. E, RIVEROS-MORENO, V, MONCADA, S

“…Nitric oxide is generated by the NO synthases, a family of isoenzymes expressed in a wide range of mammalian cells. In the vascular and nervous systems…”
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Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo : Studies with 1400W, a novel inhibitor by THOMSEN, L. L, SCOTT, J. M. J, TOPLEY, P, KNOWLES, R. G, KEERIE, A.-J, FREND, A. J

“…We have investigated the effect of N-(3-(aminomethyl)benzyl)acetamidine (1400W), a novel and highly selective inhibitor for inducible NOS (iNOS), on in vivo…”
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Characterization of CC‐chemokine receptor 7 expression on murine T cells in lymphoid tissues by Bjorkdahl, Olle, Barber, Karen A., Brett, Sara J., Daly, Maria G., Plumpton, Christopher, Elshourbagy, Nabil A., Tite, John P., Thomsen, Lindy L.

“…Summary Expression of the lymph node homing and CC‐chemokine receptor 7 (CCR7), with L‐selectin (CD62L), has been shown to divide human memory T cells into two…”
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Technical issues in construction of nucleic acid vaccines by Ertl, Peter F, Thomsen, Lindy L

“…Delivery of antigen-encoding genes by nucleic acid vaccine vectors offers tremendous advantages in power and flexibility over conventional antigen delivery…”
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Tumor cell-derived nitric oxide is involved in the immune-rejection of an immunogenic murine lymphoma by HU, De-En, DYKE, Stephanie O. M, MOORE, Alistair M, THOMSEN, Lindy L, BRINDLE, Kevin M

“…The roles played by host-derived nitric oxide (NO) in the growth and subsequent immune rejection of a immunogenic murine lymphoma were investigated by growing…”
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Local Cooperation Dominates Over Competition Between CD4+ T Cells of Different Antigen/MHC Specificity by Creusot, Remi J, Thomsen, Lindy L, Tite, John P, Chain, Benjamin M

“…Interactions between CD4(+) T cells in vivo are controlled by a balance between cooperation and competition. In this study the interaction between two…”
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Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming by Martín-Fontecha, Alfonso, Thomsen, Lindy L, Brett, Sara, Gerard, Craig, Lipp, Martin, Lanzavecchia, Antonio, Sallusto, Federica

“…Naive T cells are stimulated by antigen-presenting dendritic cells (DCs) in secondary lymphoid organs, but whether other types of cell participate in T cell…”
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Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism by Baguley, B C, Holdaway, K M, Thomsen, L L, Zhuang, L, Zwi, L J

“…Vinblastine or colchicine, administered intraperitoneally to B6D2F1 mice with advanced subcutaneous colon 38 tumours, induced substantial tumour growth delays…”
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Nitric oxide synthase activity in fresh cells from ovarian tumour tissue: relationship of enzyme activity with clinical parameters of patients with ovarian cancer by Thomsen, Lindy L, Sargent, Jean M, Williamson, Christine J, Elgie, Alena W

“…Recent studies suggest a dual role for nitric oxide (NO) in tumour biology. High concentrations of NO can mediate tumouricidal activity, whereas lower…”
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Early commitment of adoptively transferred CD4 + T cells following particle-mediated DNA vaccination: implications for the study of immunomodulation by Creusot, Rémi J., Thomsen, Lindy L., van Wely, Cathy A., Topley, Peter, Tite, John P., Chain, Benjamin M.

“…The early responses of CD4 + T cells to particle-mediated DNA immunisation were investigated using OVA-specific TCR-transgenic CD4 + T cells. Following…”
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Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid by THOMSEN, L. L, LAI-MING CHING, BAGULEY, B. C

“…Activated peritoneal macrophages, obtained from mice pretreated with Bacillus Calmette-Guérin, after exposure in vitro to flavone-8-acetic acid (FAA; NSC…”
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Serotonin involvement in the antitumour and host effects of flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid by BAGULEY, B. C, COLE, G, THOMSEN, L. L, LI ZHUANG

“…The relationship of serotonin (5-HT) receptors to the action of the experimental antitumour drugs flavone-8-acetic acid (FAA) and…”
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Potential antitumor agents. 63. Structure-activity relationships for side-chain analogs of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid by Rewcastle, Gordon W, Atwell, Graham J, Baguley, Bruce C, Boyd, Maruta, Thomsen, Lindy L, Zhuang, Li, Denny, William A

“…A series of 16 analogues of the solid tumor active compound 9-oxo-9H-xanthene-4-acetic acid (XAA), with variations in the acetic acid side chain, have been…”
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Induced recruitment of NK cells to lymph nodes provides IFN- gamma for T sub(H)1 priming by Martin-Fontecha, Alfonso, Thomsen, Lindy L, Brett, Sara, Gerard, Craig, Lipp, Martin, Lanzavecchia, Antonio, Sallusto, Federica

“…Naive T cells are stimulated by antigen-presenting dendritic cells (DCs) in secondary lymphoid organs, but whether other types of cell participate in T cell…”
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