Search Results - "Thompson, Robert W"
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Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation
Published in Immunity (Cambridge, Mass.) (19-07-2016)“…Neutrophils are the first immune cells recruited to sites of inflammation and infection. However, patients with allergic disorders such as atopic dermatitis…”
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Clinical presentation and management of arterial thoracic outlet syndrome
Published in Journal of vascular surgery (01-05-2017)“…Abstract Objective Arterial thoracic outlet syndrome (TOS) is a rare condition characterized by subclavian artery pathology associated with a bony abnormality…”
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3
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma
Published in Science translational medicine (19-08-2015)“…Increasing evidence suggests that asthma is a heterogeneous disorder regulated by distinct molecular mechanisms. In a cross-sectional study of asthmatics of…”
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4
Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis
Published in Science translational medicine (04-05-2016)“…Thymic stromal lymphopoietin (TSLP), interleukin-25 (IL-25), and IL-33 are important initiators of type 2-associated mucosal inflammation and immunity…”
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Physical therapy management, surgical treatment, and patient-reported outcomes measures in a prospective observational cohort of patients with neurogenic thoracic outlet syndrome
Published in Journal of vascular surgery (01-09-2019)“…AbstractObjectiveTo assess the results of physical therapy management and surgical treatment in a prospective observational cohort of patients with neurogenic…”
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6
Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens
Published in Nature immunology (01-12-2008)“…Classically activated macrophages are targets of intracellular bacteria such as Mycobacteria tuberculosis . Murray and colleagues find that such pathogens…”
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Incomplete deletion of IL-4Rα by LysM(Cre) reveals distinct subsets of M2 macrophages controlling inflammation and fibrosis in chronic schistosomiasis
Published in PLoS pathogens (01-09-2014)“…Mice expressing a Cre recombinase from the lysozyme M-encoding locus (Lyz2) have been widely used to dissect gene function in macrophages and neutrophils…”
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Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine
Published in American journal of physiology. Heart and circulatory physiology (01-12-2017)“…Oxidative stress plays a fundamental role in abdominal aortic aneurysm (AAA) formation. Activated polymorphonuclear leukocytes (or neutrophils) are associated…”
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Diagnosis and treatment of effort-induced thrombosis of the axillary subclavian vein due to venous thoracic outlet syndrome
Published in Journal of vascular surgery. Venous and lymphatic disorders (New York, NY) (01-10-2016)“…Venous thoracic outlet syndrome (VTOS) is uncommon but most frequently occurs in young, active, healthy patients. This condition typically presents as…”
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10
Matrix Metalloproteinase 12-Deficiency Augments Extracellular Matrix Degrading Metalloproteinases and Attenuates IL-13-Dependent Fibrosis
Published in The Journal of immunology (1950) (01-04-2010)“…Infection with the parasitic helminth Schistosoma mansoni causes significant liver fibrosis and extracellular matrix (ECM) remodeling. Matrix…”
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Acidic chitinase primes the protective immune response to gastrointestinal nematodes
Published in Nature immunology (01-05-2016)“…The physiological function of the mammalian chitinase AMCase is unclear. Wynn and colleagues show that it is dispensable for allergic lung inflammation but is…”
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12
Retnla (relmalpha/fizz1) suppresses helminth-induced Th2-type immunity
Published in PLoS pathogens (01-04-2009)“…Retnla (Resistin-like molecule alpha/FIZZ1) is induced during Th2 cytokine immune responses. However, the role of Retnla in Th2-type immunity is unknown. Here,…”
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13
Microstructural Optimization of a Zeolite Membrane for Organic Vapor Separation
Published in Science (American Association for the Advancement of Science) (18-04-2003)“…A seeded growth method for the fabrication of high-permeance, high-separation-factor zeolite (siliceous ZSM-5,$[Si_{96}O_{192}]-MFI$) membranes is reported…”
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14
Performance Metrics in Professional Baseball Pitchers before and after Surgical Treatment for Neurogenic Thoracic Outlet Syndrome
Published in Annals of vascular surgery (01-02-2017)“…Background High-performance throwing athletes may be susceptible to the development of neurogenic thoracic outlet syndrome (NTOS). This condition can be…”
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Supraclavicular decompression for neurogenic thoracic outlet syndrome in adolescent and adult populations
Published in Journal of vascular surgery (2013)“…Objective This study was conducted to better define clinical results and understand factors determining responsiveness to surgical treatment for neurogenic…”
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16
Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice
Published in The Journal of clinical investigation (01-11-2007)“…Abdominal aortic aneurysm (AAA), an inflammatory disease, involves leukocyte recruitment, immune responses, inflammatory cytokine production, vascular…”
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Smooth muscle cells from abdominal aortic aneurysms are unique and can independently and synergistically degrade insoluble elastin
Published in Journal of vascular surgery (01-10-2014)“…Background The purpose of this study was to further elucidate the role of the vascular smooth muscle cells (SMCs) in abdominal aortic aneurysm (AAA) disease…”
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Pilot feasibility study of a simple regenerative peripheral nerve interface designed to diminish cutaneous dysesthesia after supraclavicular operations
Published in Journal of vascular surgery cases and innovative techniques (01-06-2022)“…Supraclavicular operations can be associated with postoperative cutaneous dysesthesia and hypersensitivity. Regenerative peripheral nerve interfaces, created…”
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Mast Cell Tryptase Deficiency Attenuates Mouse Abdominal Aortic Aneurysm Formation
Published in Circulation research (27-05-2011)“…RATIONALE:Mast cells (MCs) contribute to the formation of abdominal aortic aneurysms (AAAs) by producing biologically active mediators. Tryptase is the most…”
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Critical Role of Mast Cell Chymase in Mouse Abdominal Aortic Aneurysm Formation
Published in Circulation (New York, N.Y.) (15-09-2009)“…Mast cell chymase may participate in the pathogenesis of human abdominal aortic aneurysm (AAA), yet a direct contribution of this serine protease to AAA…”
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