Search Results - "Thompson, Richard L"
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Resolution of herpes simplex virus reactivation in vivo results in neuronal destruction
Published in PLoS pathogens (05-03-2020)“…A fundamental question in herpes simplex virus (HSV) pathogenesis is the consequence of viral reactivation to the neuron. Evidence supporting both…”
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2
De Novo Herpes Simplex Virus VP16 Expression Gates a Dynamic Programmatic Transition and Sets the Latent/Lytic Balance during Acute Infection in Trigeminal Ganglia
Published in PLoS pathogens (01-09-2016)“…The life long relationship between herpes simplex virus and its host hinges on the ability of the virus to aggressively replicate in epithelial cells at the…”
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3
Modulated Fluorescence in LB Films Based on DADQs—A Potential Sensing Surface?
Published in Molecules (Basel, Switzerland) (17-06-2022)“…Novel fluorescent Langmuir-Blodgett (LB) films have been constructed from three different amphiphilic dicynaoquinodimethanes (DADQs). The DADQs varied in…”
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4
Targeted Promoter Replacement Reveals That Herpes Simplex Virus Type-1 and 2 Specific VP16 Promoters Direct Distinct Rates of Entry Into the Lytic Program in Sensory Neurons in vivo
Published in Frontiers in microbiology (24-07-2019)“…Infection and life-long residence in the human nervous system is central to herpes simplex virus (HSV) pathogenesis. Access is gained through innervating…”
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Electrospinning Superhydrophobic Fibers Using Surface Segregating End-Functionalized Polymer Additives
Published in Macromolecules (23-08-2011)“…We describe here a facile route for the in situ modification of the surface properties of fibers produced by electrospinning polystyrene containing small…”
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6
The Impact of Plasticizer and Degree of Hydrolysis on Free Volume of Poly(vinyl alcohol) Films
Published in Polymers (18-09-2018)“…The effect of plasticizer species and the degree of hydrolysis (DH) on the free volume properties of poly(vinyl alcohol) (PVA) were studied using positron…”
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7
Controlled Structure Evolution of Graphene Networks in Polymer Composites
Published in Chemistry of materials (13-03-2018)“…Exploiting graphene’s exceptional physical properties in polymer composites is a significant challenge because of the difficulty in controlling the graphene…”
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8
De novo synthesis of VP16 coordinates the exit from HSV latency in vivo
Published in PLoS pathogens (01-03-2009)“…The mechanism controlling the exit from herpes simplex virus latency (HSV) is of central importance to recurrent disease and transmission of infection, yet…”
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Influence of PVAc/PVA Hydrolysis on Additive Surface Activity
Published in Polymers (14-01-2020)“…This aims to establish design rules for the influence of complex polymer matrices on the surface properties of small molecules. Here, we consider the…”
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10
Molecular weight dependent vertical composition profiles of PCDTBT:PC71BM blends for organic photovoltaics
Published in Scientific reports (13-06-2014)“…We have used Soxhlet solvent purification to fractionate a broad molecular weight distribution of the polycarbazole polymer PCDTBT into three lower…”
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11
A forward phenotypically driven unbiased genetic analysis of host genes that moderate herpes simplex virus virulence and stromal keratitis in mice
Published in PloS one (20-03-2014)“…Both viral and host genetics affect the outcome of herpes simplex virus type 1 (HSV-1) infection in humans and experimental models. Little is known about…”
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12
Water-Resistant Surface Modification of Hydrophobic Polymers with Water-Soluble Surfactant Additives
Published in Polymers (03-10-2021)“…Water-soluble nonionic surfactant, pentaethylene glycol monododecyl ether, C12E5, spontaneously blooms to the surface of spin-cast hydrophobic polyisoprenes,…”
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13
Herpes simplex virus and the lexicon of latency and reactivation: a call for defining terms and building an integrated collective framework
Published in F1000 research (2016)“…The field of herpes simplex virus (HSV) latency and reactivation has been marked by controversy, which is not unexpected considering the complexities of the…”
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14
Infectious Herpes Simplex Virus in the Brain Stem Is Correlated with Reactivation in the Trigeminal Ganglia
Published in Journal of virology (15-04-2019)“…Herpes simplex virus (HSV) establishes latency in neurons of the peripheral and central nervous systems (CNS). Evidence is mounting that HSV latency and…”
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15
Multi-End-Functionalized Polymers: Additives to Modify Polymer Properties at Surfaces and Interfaces
Published in Macromolecules (20-03-2007)“…An ongoing challenge in polymer science is the preparation of materials with specific surface properties which differ from that of the bulk, for example,…”
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Modifying and managing the surface properties of polymers
Published in Polymer international (01-02-2008)“…An ongoing challenge in polymer science is the preparation of materials with bespoke surface properties which differ from that of the bulk, for example…”
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17
Braiding, branching and chiral amplification of nanofibres in supramolecular gels
Published in Nature chemistry (01-04-2019)“…Helical nanofibres play key roles in many biological processes. Entanglements between helices can aid gelation by producing thick, interconnected fibres, but…”
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18
Alphaherpesvirus Latency and Reactivation with a Focus on Herpes Simplex Virus
Published in Current issues in molecular biology (2021)“…We are at an interesting time in the understanding of alpha herpesvirus latency and reactivation and their implications to human disease. Conceptual advances…”
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Surfactant and Plasticizer Segregation in Thin Poly(vinyl alcohol) Films
Published in Langmuir (26-01-2016)“…The vertical depth distributions of individual additive components [cetyltrimethylammonium bromide (CTAB), deuterated pentaethylene glycol monododecyl ether (d…”
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20
The influence of ambient cure chemistry and stoichiometry on epoxy coating surfaces
Published in RSC advances (10-10-2022)“…The surface properties of epoxy resin coatings influence their function as substrates for subsequent coats. Variation in ambient cure conditions (temperature…”
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